Buspar for Anxiety: Mechanism of Action, Dosage, Reviews
Anxiety disorders are the most prevalent psychiatric disorders in the world. Scientists have reported that these disorders may be underrecognized and undertreated. Treatment is necessary when a person experiences severe distress and/or complications associated with the disorder. Buspar has proved its efficiency in resultative fighting against anxiety.
Buspar's Mechanism of Action
The main active ingredient of the drug is buspirone. This is an anxiolytic substance that differs in pharmacological properties from benzodiazepines, barbiturates and other sedative and hypnotic medical remedies. Studies have shown that buspirone has a high affinity for 5-hydroxytryptamine 1A receptors and a moderately pronounced affinity for dopamine D2 receptors in the brain. In simple words, Buspar affects chemicals that can be unbalanced in people with anxiety.
The effect of the drug occurs gradually; you will see the first results in 1-2 weeks. The maximum effect is achieved after 4 weeks.
Buspar does not cause addiction, it can be canceled without negative consequences for mental health. Patients cannot develop tolerance to this pharmaceutical substance.

The drug helps to cope with the following diseases / conditions:
- generalized anxiety disorder
- vegetative-vascular dystonia, a type of dysautonomia, which affects vascular system
- panic disorders
- alcohol withdrawal syndrome (as a substituent of complex therapy)
- depression (as an additional remedy in the therapy)
The use of Buspar leads to complete remission. However, withdrawal of the drug may lead to a return of symptoms.
The medication can cause a number of side effects, including restless legs syndrome (an uncontrollable urge to move the legs), dizziness, nausea, headache, and increased irritability. It is known that some patients with psychological / psychiatric disorders are prone to suicide. Fortunately, Buspar overdose is not enough to execute suicidal intentions. It is typically resolves with full recovery. However, as stated by Tyler K. Wilson and Jayson Tripp (StatPearls article, last updated February 2019), the risk of additional drug overdose exists, so relatives and healthcare experts should also investigate if a patient has administered extra medications.
It is important: the drug is not intended to treat anxiety symptoms caused by everyday stress or a stressful situation. In such cases, regular rest and herbal remedies will help to overcome the problem. Therefore, if you are simply very tired at work and have experienced stress due to bad words of your boss, do not take Buspar. It is intended for more serious cases.
Buspar Dosage, Features of Use
It is usually recommended to start therapy with 15 mg twice a day. Every 2-3 days, increase the dosage by 5 mg / day, until the desired effect is achieved, which should appear in the period up to 14 days.
The maximum dose of the drug is 60 mg / day, an increase in dose is associated with an elevated risk of side effects. The usual therapeutic dose is 20-30 mg / day. The daily dose should be divided into 2-3 portions.
The product is offered in 5mg–30mg dosage range.
Eating food can slow the absorption of the drug in the gastrointestinal tract.
If the medication did not start working after the expiration of the expected “deadline”, you need to consult a doctor and choose another medical remedy, such as benzodiazepine or an antidepressant.
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Buspirone Reviews
There are many negative reviews about buspirone on the Internet, but such a situation this is often due to the fact that people do not have the patience to administer the pills for a long period (as mentioned above, it takes 1-2 weeks for the effect to occur) or simply they don’t have proper information about Buspirone administration. Other people write on forums that the medicine reduces sociopathy, increases interest in various activities. For some, a work phone call to another person is an excruciation, but dissolving the tablet eliminates the problem.