women propecia

Propecia for Women – Can Finasteride Be Used by Females?

Hair loss is a widespread problem which might affect not only men. Some women also suffer from this condition, naturally, they want to find efficient and safe remedy. Propecia is a male medication which helps to fight baldness. Can women benefit from this?

Finasteride Indications

Finasteride is a component of drugs used to treat prostatic hyperplasia and baldness. The drug manufactured under the brand name Propecia, is specifically designed for the treatment of male pattern baldness (androgenic type). It was originally created to treat prostate enlargement, but researchers noticed that the subjects also experienced increased hair growth, which led to the use of finasteride to combat baldness.

Contraindications

Finasteride has contraindications for use with:

  • hypersensitivity to the components of the drug
  • malignant tumors in the prostate gland
  • obstruction of the channels of the urine drainage
  • pregnancy or desire to become pregnant
  • negative reaction of the body to the use of finasteride
  • severe liver pathologies and symptoms of hepatic encephalopathy.

The administration of this therapeutic agent is not indicated for use by patients undergoing hemodialysis.

Females of reproductive age, and especially women during the pregnancy period, should completely abandon the use of the medication. It should be remembered that powder or crushed fragments of a tablet containing finasteride can enter the bloodstream through the pores of the skin and cause irreparable harm to the fetus, this especially concerns intrauterine development of male infants. It should be borne in mind that the therapeutic effect of this medication is associated with blocking the synthesis of dihydrotesterone (DHT), which is responsible for the formation of boys’ genitals in the womb.

Can Women Use Dinasteride? Have Clinical Trials Been Performed?

Finasteride official instructions contain no information about possibility of using finasteride by women (they only contain precaution information, which was described above).

There were several studies in which scientists evaluated the efficiency and use of the medication in women. The latest review was made by A.C. Hu et al. (International Journal of Dermatology, 2019), the scientists reported about 65 studies with participation of more than 2,600 female patients. However, according to the scientists’ opinion, future long-term studies are needed to fully evaluate prospects of finasteride use in female population.

R. Oliveira-Soares and others (International Journal of Trichology, 2018) concluded that finasteride is useful n premenopausal patients with female pattern hair loss. However, they had some concerns with regard to eventual long-term side effects of the pharmaceutical.

Conclusion

Thus, if you are a woman and plan to have children, finasteride is definitely contraindicated for you. This medication is not yet officially approved for use by women. Middle-aged women who don’t plan pregnancy in the future can potentially use this medicine (as there are some scientific confirmations). Talk your physician. However, it is probably better to search for safer solutions.

buspar for anxiety

Buspar for Anxiety: Mechanism of Action, Dosage, Reviews

Anxiety disorders are the most prevalent psychiatric disorders in the world. Scientists have reported that these disorders may be underrecognized and undertreated. Treatment is necessary when a person experiences severe distress and/or complications associated with the disorder. Buspar has proved its efficiency in resultative fighting against anxiety.

Buspar’s Mechanism of Action

The main active ingredient of the drug is buspirone. This is an anxiolytic substance that differs in pharmacological properties from benzodiazepines, barbiturates and other sedative and hypnotic medical remedies. Studies have shown that buspirone has a high affinity for 5-hydroxytryptamine 1A receptors and a moderately pronounced affinity for dopamine D2 receptors in the brain. In simple words, Buspar affects chemicals that can be unbalanced in people with anxiety.

The effect of the drug occurs gradually; you will see the first results in 1-2 weeks. The maximum effect is achieved after 4 weeks.

Buspar does not cause addiction, it can be canceled without negative consequences for mental health. Patients cannot develop tolerance to this pharmaceutical substance.

busiron for anxiety

The drug helps to cope with the following diseases / conditions:

  • generalized anxiety disorder
  • vegetative-vascular dystonia, a type of dysautonomia, which affects vascular system
  • panic disorders
  • alcohol withdrawal syndrome (as a substituent of complex therapy)
  • depression (as an additional remedy in the therapy)

The use of Buspar leads to complete remission. However, withdrawal of the drug may lead to a return of symptoms.

The medication can cause a number of side effects, including restless legs syndrome (an uncontrollable urge to move the legs), dizziness, nausea, headache, and increased irritability. It is known that some patients with psychological / psychiatric disorders are prone to suicide. Fortunately, Buspar overdose is not enough to execute suicidal intentions. It is typically resolves with full recovery. However, as stated by Tyler K. Wilson and Jayson Tripp (StatPearls article, last updated February 2019), the risk of additional drug overdose exists, so relatives and healthcare experts should also investigate if a patient has administered extra medications.

It is important: the drug is not intended to treat anxiety symptoms caused by everyday stress or a stressful situation. In such cases, regular rest and herbal remedies will help to overcome the problem. Therefore, if you are simply very tired at work and have experienced stress due to bad words of your boss, do not take Buspar. It is intended for more serious cases.

Buspar Dosage, Features of Use

It is usually recommended to start therapy with 15 mg twice a day. Every 2-3 days, increase the dosage by 5 mg / day, until the desired effect is achieved, which should appear in the period up to 14 days.

The maximum dose of the drug is 60 mg / day, an increase in dose is associated with an elevated risk of side effects. The usual therapeutic dose is 20-30 mg / day. The daily dose should be divided into 2-3 portions.

The product is offered in 5mg–30mg dosage range.

Eating food can slow the absorption of the drug in the gastrointestinal tract.

If the medication did not start working after the expiration of the expected “deadline”, you need to consult a doctor and choose another medical remedy, such as benzodiazepine or an antidepressant.

An interesting stuff: Erectile Dysfunction and Depression: Often Coexist but Can be Overcome

buspar reviews

Buspirone Reviews

There are many negative reviews about buspirone on the Internet, but such a situation this is often due to the fact that people do not have the patience to administer the pills for a long period (as mentioned above, it takes 1-2 weeks for the effect to occur) or simply they don’t have proper information about Buspirone administration. Other people write on forums that the medicine reduces sociopathy, increases interest in various activities. For some, a work phone call to another person is an excruciation, but dissolving the tablet eliminates the problem.

zetia high cholesterol

How Does Zetia Work? Short Overview of this Lipid-Lowering Agent

Coronary heart disease (CHD) is one of the dominant causes of deaths in adults in the United States. CHD is linked to elevated levels of “bad” cholesterol and decreased rates of “good” chol. Proper treatment should include nutrition adjustments, physical exercises (at least long-lasting walking), and bodyweight loss. However, medication therapy may be a requirement.

Lowering Lipids in the Blood with Zetia

There are many medications that helps to decrease cholesterol in the bloodstream. Among them are bile acid sequestrants, statins, fibric acids, etc. However, there is a unique drug which is distinct from others. Ezetimibe (trade name Zetia) has no inhibitory effect on cholesterol production by the liver, it also doesn’t accelerate excretion of bile acid.

The medication localizes in the intestine and block absorption of cholesterol & some plant-based sterols. Ingestion of high-fat food has no influence on the bioavailability of Zetia (but this doesn’t mean that you can overeat French fries, burgers, cheese and other food with high content of fat, scroll down to know why).

Healthcare specialists typically prescribed Zetia (and clinical studies are also centered on the combination therapy), but monotherapy is also possible. According to the UK scientists Daniel Hammersley and Mark Signy (Western Sussex Hospitals NHS Trust, 2017), one-type treatment may be applied in the following cases:

  • treatment of primary hypercholesterolaemia in persons with contraindications to statin administration
  • hypercholesterolaemia in folks who cannot tolerate statin pharmaceuticals

Effect of Ezetimibe: Scientific Data

IMPROVE-IT trial performed by dozens of investigators and 2574 collaborators (published in 2015) showed Zetia substantially decreased incidence of severe cardiovascular events in people with cardiovascular diseases and low rates of “good” cholesterol. Moreover, incremental decreasing of cholesterol to rates below previous targets which were measured by doctors provided extra benefits.

According to American researchers Jigna Patel and others (Baylor University Medical Center, 2003), coadministration of Zetia plus lovastatin (Mevacor) showed greater effectiveness than lovastatin alone or ezetimibe alone. The combotherapy provided −39% reduction, while lovastatin monotherapy caused −25% decrease and Zetia led to just −19% reduction.

Hence it can be concluded Zetia provides less pronounced effect when used as monotherapy. Conjunction with statins is more efficient, however, this option may be unsuitable for some individuals.

When Is Zetia Contraindicated? What Are Potential Side Effects?

The medicine has high safety profile and is usually well-tolerated in different subgroups of patients. Nonetheless, as in case with any pharmaceutical product, Zetia has several contraindications, including:

  • increased sensitivity to principal or auxiliary components (fillers) of the drug
  • moderate of severe liver insufficiency
  • active liver disease (when combined with a statin medication)
  • pregnancy or breastfeeding (in combination with statins)

Sometimes, patients may experience side effects:

  • liver damage and disorders (especially when the drug is coadministered with statins)
  • muscle pain
  • weakness and tenderness
  • allergic reactions, such as itching, rash, dizziness, and trouble breathing (allergy is rarely observed)
healthy diet for cholesterol

Is It Enough for Successful Treatment?

No, just taking Zetia is not enough for adequate therapy of increased cholesterol. Before starting treatment, patients should switch to an appropriate hypocholesterolemic diet and adhere to this diet during the entire period of therapy. The diet should be based on the following principles:

  • limiting fried food
  • choosing low-fat milk and dairy products
  • eating more fruits and vegetables
  • consuming whole-grained food, poultry, lean fish, nuts and beans
  • curbing soft beverages and sugary food

In addition, scientists have revealed food and food supplies with hypocholesterolemic effects. As stated by Ruitang Deng (University of Rhode Island, 2009), these include fiber or polysaccharides, soy protein, phytoestrogens, and probiotic bacteria (it was claimed that additional studies are needed to evaluate efficacy and safety of probiotics and anti-cholesterol agents).

A related topic by Canadian Health&Care Mall experts: Treatment Diabetes and Overweight

can high cholesterol medications cause ed

Can High Cholesterol Medications Cause Erectile Dysfunction (ED)?

Healthcare experts are adamant high cholesterol levels are harmful for the health. There are many causes of elevation, but anyway patients who have faced such a problem need an appropriate treatment. Mercifully, there are many medications that really work by decreasing chol levels through different mechanism. There is one awkward moment: some of them might cause problems with male potency.

Side Effects of Medicines and Erectile Dysfunction

ED might be induced by organic and psychogenic factors. Some medicines belong to possible organic causes. The list of potential offenders is extensive, so we will name only some groups with examples:

statins side effects
  • diuretics and high arterial pressure medications (Vasotec, Capoten, Tenormin)
  • anti-anxiety drugs and antidepressants (Zoloft, Prozac, Serax)
  • antihistamines (Antivert, Vistaril)
  • antiarrythmic drugs (Norpace)
  • medications for Parkinson’s disease treatment (Biperiden)
  • NSAIDs (Naproxen)
  • remedies for treating elevated cholesterol rates (Lipitor)

By the way, ED may be caused by diabetes. Read our comprehensive article:

Diabetes-Induced Erectile Dysfunction: Prevention and Treatment

A Short Overview of High-Chol Medications

Before taking any medication, first and foremost, you need to have a medical consultation and determine rates of cholesterol in the body. Well, how to quantify level of cholesterol in the blood? There are special blood tests, which are available in many clinics. It is recommended to regularly undergo them, because people with high cholesterol levels may have absolutely no symptoms.

high cholesterol and erectile dysfunction

Statins are the most prescribed medications for treating the condition. This subgroup of anti-chol pharmaceuticals includes Lipitor, Fluvastatin, Pravastatin, and Lovastatin. They inhibit cholesterol synthesis by the liver. This leads to a decrease in amount of the so-called “bad cholesterol” in the blood. However, statin drugs cannot destroy already formed plaques in vessels.

There are also other types of high-chol medications, however, we will pay more attention to statins, as they have been associated with unpleasant side effects for men’s health.

Can High Cholesterol Medications (Statins) Lead to ED in Men?

Erectile dysfunction is not a widespread effect, and it is even not indicated in many medical articles describing statins. However, links to ED were found in several scientific studies.

Let’s analyze some of them. Xiang Cai, Ye Tian et al., Chinese researchers, reported in 2014 that treatment with statins might decrease testosterone and aggravate impotence symptoms. Testosterone is an essential hormone for healthy sex drive and its reduction might be fatal for sexual life of males who already suffer from ED.

However, as they say, nothing is bad without being good for something. Other studies show statins might actually treat ED. For example, John B. Kostis and Jeanne M. Dobrzynski at Rutgers Robert Wood Johnson Medical School (2019) studied a large array of data and stated: small improvement in erectile function is observed with statins. Impotence may be partially caused by high cholesterol, so statin meds can help to eliminate an underlying cause. Hence, it is not a good idea to abandon the medication intake, check your healthcare provider first.

nexium gastritis treatment

Gastritis Treatment: Nexium (Esomeprazole) vs Natural Remedies

Chronic gastritis is the most common condition of the gastrointestinal tract, according to some data, its prevalence may reach 60%. Fortunately, there are many powerful remedies that can help to overcome it. Nexium is one of them. It is significantly inferior to omeprazole in terms of popularity, however, it is still widely used. How does it treat gastritis? What’s better: Nexium or natural remedies?

Gastritis, Its Causes and Symptoms

Gastritis is a general term covering a group of illnesses that have one common feature: inflammation, irritation or erosive lesions of stomach lining. According to some authors, gastritis is more likely a condition and not a disease, since in many cases inflammation of the gastric mucosa does not lead to the appearance of clinical symptoms.

Gastritis development may be linked to Helicobacter pylori, frequent/permanent psychoemotional stress, personal problems, improper nutrition, harebrained fasting, alcohol overconsumption, smoking, cocaine, severe illness, autoimmune disorders, using an anti-pain medicine (NSAID) for an extended period, eating dry food and some other causes.

Related topic: Diclofenac for Pain Relief

Some scientists consider the term “gastritis” inappropriate, since a serious mucosal lesion can be almost asymptomatic, while gastrointestinal upsets such as pain, nausea, belching, and loose stools can occur with a slight inflammation of the stomach or even in its absence. If there are no structural changes in the gastric mucosa, the diagnosis of functional dyspepsia can be used. In Japan, a country with a very high rate of stomach cancer (the incidence in men is 77.9 and in women 33.3 per 100,000 population), doctors combine the diagnoses of chronic gastritis and functional dyspepsia, thereby indicating the presence or absence of mucosal changes gastric lining and / or related clinical symptoms.

The most common cause of chronic gastritis worldwide is H. pylori infection. This bacterium causes progressive damage to the gastric mucosa and plays an important causative role in a number of important diseases, including duodenal ulcer, gastric ulcer, and even stomach adenocarcinoma (a type of cancer).

Well, what are symptoms of gastritis? The most common ones are as follows:

  • heartburn
  • pain in the abdominal area
  • appetite decrease or loss
  • nausea
  • hiccups, especially after eating irritative food
  • dyspepsia (indigestion)
  • stomach upset
  • dark stools

What is Nexium? How Does It Work?

A pharmaceutical substance called esomeprazole was patented back in 1993, however, it received approval for medical use only 7 years later – in 2000. It is now available as a non-branded (generic) medication and sold OTC in many countries. According to ClinCalc, it was 69th most prescribed medication in the United States (but its position slightly worsened in comparison with the previous year). Branded name of the product is offered by AstraZeneca company.

buy nexium otc

The drug comes in the form of delayed-release tablets or delayed-release capsules. It also has enteric coating, as the active substance is actively destroyed by the stomach acid. There two typical dosages: 20mg and 40mg.

Nexium can be ordered here: Product page.

The medication belongs to the category of medications called proton pump inhibitors (PPIs). They have similar mechanism of action. Like other PPIs, Nexium works by reducing the amount of gastric acid made by the stomach. Therefore, stomach mucosa receives a possibility to recover from damage caused by acidic gastric juice.

An important fact: stress-induced gastritis can be prevented by early use of PPIs. Rishi Megha and Peter P. Lopez, StatPearls Publishing, 2019.

The medication work best when used on a regular basis. Try to take it at the same time every day. Continue the administration till the end of prescribed period, even if you feel improvement of your symptoms. Sudden cancellation can lead to a quick return of the condition. Tell your healthcare provider if your condition worsens or does not improve. Important: this medication is very similar to omeprazole (Prilosec, Losec), so don’t take omeprazole-containing medicines while treating with Nexium.

Natural Remedies for Gastritis Treatment

Besides medical therapy, a patient should take attention to natural methods of gastritis treatment. Let’s consider main of them.

gastritis diet

Proper Diet

Doctors say that diet is a cornerstone of successful gastritis treatment. The main rule: food should not be very acidic, salty and bitter. It should be gentle and not irritate the gastric mucosa, so coarse and hot food is also contraindicated, especially when the disease is in exacerbated phase.

If you suffer from gastritis symptoms, you can eat porridge (cereals), soups, lean meat and fish, boiled vegetables, non-acidic fruits. Drink non-carbonated and non-caffeinated drinks. Dairy products, sweets, gluten-containing foods can contribute to inflammation.

Herbs and Plants

Some herbs may help to combat gastritis. These include green tea, rosemary, aloe vera, chamomile, calendula, thyme, lemon balm, and mint. Don’t choose herbal teas on your own, always consult a healthcare professional. Some of them may increase gastric acidity, while others, vice versa, may decrease it. Depending on the type of disease you have, an effect may be inappropriate.

Jelly prepared on the basis of flax seeds is considered a useful remedy. It “wraps” the gastric mucosa, positively affecting its condition. Other folk remedies include cabbage juice, honey, coconut oil and water, turmeric, juice from carrots and potatoes.

natural treatment of gastritis

Supplements

There are several over-the-counter supplies that might be helpful in case of gastritis. Among them are chlorophyll, essential oils, probiotics, and garlic extract. Supplements are sold as OTC products; despite that it would be a good idea to consult a healthcare expert before the beginning of self-prescribed therapy.

Nexium vs Natural Treatment

When it comes to comparison between these two methods, it should be said that Nexium may act quicker and be more effective. Natural herbs may take longer time to show necessary effect. However, the proper diet is a must-follow thing in any case, without it your efforts will be in vain.

diclofenac for pain

Diclofenac for Pain Relief: Here’s How It Helps to Combat Aches and Pains

Painkillers are probably the most popular drugs in the world, as any person experiences severe pain or ache (requiring medical treatment) at least once during lifetime, usually much more. Diclofenac is a well-known and widely used painkilling medication. What are its key features? How does it work? Are side effects possible to occur?

What is Diclofenac?

Diclofenac is a medication which belongs to NSAID (nonsteroidal anti-inflammatory drug) category. It helps to fight mild-to-moderate painful sensations, and also to eliminate symptoms of rheumatoid arthritis and osteoporosis (bone weakening disease). Cataflam brand, immediate-release pills, are also administered for menstrual cramps.

This pharmaceutical substance was developed in 1966. It was initially prescribed to treat rheumatologic diseases, however, the sphere of its application significantly widened.

Use of Diclofenac for Treating Ache and Pain

This pharmaceutical product relieves pains and aches, in addition, it helps to cope with swelling (caused by inflammation) and joint stiffness. So a patient can perform everyday activities with regular easiness.

What’s the difference between aches and pains?

Ache is a discomfortable feeling which continues for some time. Typically, people associate it with long-lasting pain in some part of the body, for example, headache, toothache, backache, etc. If you have trained in a gym after a long break, you will experience muscle ache (or, in worse case, slight aching pain in the elbows or knees). Pain has more sudden nature and is more pronounced, so it is hard to ignore it. Say, a dentist pulled your tooth out, you will most probably experience extreme pain, so to prevent it the doctor prescribes painkillers in advance.

ache vs pain

How Does Diclofenac Work?

The pill works by decreasing substances in the body that lead to inflammation and pain. It stops the activity of cyclooxygenase (COX) enzyme (officially named prostaglandin-endoperoxide synthase). It is responsible for formation of prostanoids, more precisely, their type called prostaglandins, which are mediators of inflammatory and allergic reactions. The substance reduces the intracellular level of free arachidonic acid (E. Ku et al., Am J Med. 1986), which is converted by COX to prostaglandins.

If a person has an injury, gout, rheumatism etc., the body begins to produce prostaglandin substances which cause pain, aches, inflammation, and swelling. It should be noted that these effects are natural for human bodies, but sometimes they are annoying and insufferable, so treatment is necessary. The drug blocks production of prostaglandins by affecting COX enzyme, due to which analgesic action is achieved. A desired effect usually occurs after the first dosage, but if you take Diclofenac regularly, its anti-inflammatory action may build up with subsequent doses.

However, some scientists have noted that often the analgesic effect of diclofenac, which manifests itself along with the anti-inflammatory, is not caused by suppression of inflammatory processes, but develops by involving specific mechanisms that are not the same in different NSAIDs. This confirms the fact that the analgesic effect of NSAIDs is not always associated with inhibition of COX.

Like other NSAIDs, Diclofenac produces a symptomatic effect, that is it only treats symptoms but provides no cure for a disease.

On the picture below, you can see a mechanism of NSAIDs’ action, which generally applies to the product described in this article.i

how does diclofenac work

Warnings and Side Effects of the Medication

Diclofenac is a highly efficient medicine, but its use may be associated with severe side effects. Some specialists even propose to fully prohibit it due to elevated risk of cardiovascular events linked to Diclofenac administration. According to a Danish-American study by Morten Schmidt et al. (BMJ, 2018), the drug poses a hazard of major adverse cardiovascular events compared with non-administration, paracetamol and other NSAID use within 30 days of initiation. But from this it can be concluded that short-term use is generally safe for health. Despite that, new findings of above-mentioned and other researchers lead to removal of Diclofenac from an OTC catalogue in some countries.

The list of other potential adverse events of the medication include:

  • development of ulceration or bleeding
  • reversible liver damage
  • worsening of kidneys’ functioning
  • anxiety, depression, irritability and similar mental health effects (rarely)

Avoid consumption of alcohol when treating with Diclofenac. Such a combination may increase a risk of gastrointestinal bleeding.

If you use any medication for pain, allergic disease or cold, discuss the possibility of Diclofenac co-administration with pharmacist or doctor (or at least carefully read a leaflet with composition and instructions). Some meds may contain substances that are similar to Diclofenac, and you can get too much of painkilling substance.

The Bottom Line

Diclofenac acts effectively and can be used over-the-counter in many countries. However, don’t overuse it, as long-lasting administration may be harmful for your health. Moderation is a key, moreover, if your systems don’t go away during a long time, probably their underlying cause is deep and requires a more serious medical intervention.

You might be interested in: Treatment and Causes of Radiculitis

erectile dysfunction and depression

Erectile Dysfunction and Depression: Often Coexist but Can be Overcome

Depression and erectile dysfunction are widespread conditions nowadays. Moreover, they often coexist. A patient then faces a doubled formidable problem which seems to be hard for overcoming. But one shouldn’t fall into desperation, there is a way out.

Depression – a Modern-Day Scourge

According to the study by Jinghui Wang, Xiaohang Wu et al. (BMJ Open. 2017), the prevalence of depression and depressive symptoms amongst outpatients in different specialties was in a range of between 17 and 50%. Their presence is more widespread in developing countries than in developed ones. Along with anxiety disorders depression is one of the most dominant mental illnesses. It may lead to disability, worsening of personal and social relationship. When it coexists with other diseases, it may complicate the treatment process.

The most common psychical manifestations and physical symptoms of the condition include:

  • persistent sadness
  • impaired self-esteem
  • hopelessness
  • pessimistic outlook
  • no desire to do everyday activities
  • appetite changes
  • apathy
  • problems with falling asleep and/or sleeping
  • fatigue

Depression should be diagnosed by psychotherapists. There are no reliable medical tests (like blood testing or X-rays) which can precisely indicate its presence. There are two widely accepted ways of combating depression: using medications and  talk therapy. However, some pharmaceuticals may lead to ED or worsen it, so be careful in choosing the right remedy.

Erectile Dysfunction (ED) and Its Causes

The erect penile organ has always been a symbol of sexual prowess, so any problems with achieving and/or maintaining an erection may be perceived as a personal tragedy.

Erectile dysfunction is a multidimensional disorder which may have different causes (organic, psychogenic, and mixed). Organic causes, in their turn, are divided into endocrine and nonendocrine (Faysal A. Yafi et al., Nat Rev Dis Primers, 2017). Nonendocrine ones are the most common, they include abnormalities of blood flow, medical treatment, and physical damage caused by surgery. Endocrine causes are associated with decreased testosterone levels; however, the exact mechanisms have not been completely revealed.

depression and ed

It should be borne in mind that ED might be a predictor of cardiovascular events. That’s why it is important to conduct a completed diagnosis once a patient notices first warning symptoms.

An interesting tidbit: too frequent watching of adult entertainment videos (pornography) may cause symptoms of ED when it comes to real sex with a partner. Studies have shown that some males over 40 need to watch more and more extreme videos with time to achieve successful erection. Along with this, they experience erection troubles with their partners. Thankfully, the problem can be easily eliminated, a man just needs to refuse to watch porn for several weeks in order to put the normal sexual performance back the way it was meant to be.

Correlation Between ED and Depression

Males suffering from erectile dysfunction often feel anger, sadness, lowered self-esteem, etc. If the condition is left untreated (or treatment doesn’t provide desired help), depression may develop. Vice versa, a depressive disorder may develop first, and ED accompanies it some time after. This may be associated with declining in testosterone production caused by the so-called “bad stress” (while “good stress” boosts synthesis of “T hormone”). According to estimates by some researchers, about 13-20% of men with ED also have anxiety or depression.

Read a closely related topic by Canadian Health Care Mall specialists: Viagra and Antidepressant-Associated Erection Problems

How to Deal with these Problems Simultaneously?

The most important thing is that antidepressants may worsen erection problems. It has been proven that anti-depression pharmaceuticals are often a cause of impotence or its deterioration.

treat depression and ed

There are two possible scenarios.

  • The first one: a male had depression and was prescribed antidepressants which led to ED. Probable solutions: (1) cancel antidepressants’ administration under a doctor’s guidance, apply for a psychotherapy or use another alternative method of therapy; (2) continue therapy with antidepressants in the same or decreased dosages and receive an anti-ED treatment like Viagra (less preferred option), cancel their intake if possible or switch to another medicine for treating depression (preferable options). Selective serotonin reuptake inhibitors are a group of antidepressants that are linked to sexual problems.
  • The second one: a man developed erection disorder. Amidst it, a depressive condition appeared. In this case, prescription of meds for treating depression might lead to exacerbation of ED. The solution is to treat impotence ASAP and consult a sexologist or psychotherapist.

Remember: both depression and ED are treatable. If you encounter one of these problems or both, don’t despair. There are many options that can help you with both mental issues and ED.

viagra heart disease

Viagra-Like Drugs for Heart Attack: Could They Reverse Cardiovascular Events?

Viagra is a very popular drug with those who suffer from erection problems. Numerous research papers prove that Viagra is a powerful remedy for combatting erectile dysfunction. But the capabilities of the drug are not limited to this function. It can be also a great option for treating various diseases, in particular, heart failure, which is a very dangerous condition.

Viagra-Like Drugs and Heart Failure Treatment

Scientists have recently revealed that drugs, usually taken in case of problems with erection, are also effectual for treatment and prevention of heart failure. Among them is Viagra-like drug tadalafil. People, who face this heart disease, have a poor heart muscle, which fails to pump blood properly. Consequently, organs and tissues don’t get enough oxygen to maintain vital functions. According to The Centers for Disease Control and Prevention (CDC) approximately 6 million of American adults are diagnosed this condition. Half of them live fewer than 5 years after learning the doctor’s verdict.

viagra heart disease

Prof. Trafford together with his team conducted a study, aimed at revealing the properties of tadalafil. This drug belongs to the same category as Viagra (brand name of sildenafil) and is marketed as Cialis. The experiment was made on sheep, which were given tadalafil for removing symptoms of heart failure. Humans usually take tadalafil to escape from problems with erection. The 3 week research showed the significant improvement of the state of animals’ hearts. This drug contributed to the enhancement of the contraction of the heart as well as restoration of the organ’s reaction to the hormone, called epinephrine. Poor response to it leads to the heart failure. Professor claims, that the effect, experienced by the animals, will be the same in people. He adds that individuals, who take tadalafil for treating bad erection, unwittingly help their heart to opposite negative impact of ageing, bad habits and unfavorable conditions.

Another remedy, which is also probably good in dealing with heart conditions, is Viagra (sildenafil). It’s a revolutionary product, which helped millions of males to combat sexual dysfunction. Like tadalafil Viagra only theoretically can be beneficial for treating heart failure. As there is no clear scientific research in this respect further studies are required.

The main question is whether it’s safe to take Viagra if the patient has heart disease.

Some doctors insist that Viagra shouldn’t be taken by individuals with heart disease of certain type. It can cause dangerous outcomes.

You might be interested in: Diabetes and Heart Disease – Is There an Interconnection?

Side Effects of Viagra and ED Treatment

viagra heart side effects

There are certain side effects of sildenafil. Firstly, it can potentially minimize the pressure of the blood. Secondly, the interaction with nitrates is observed. Being a vasodilator, which dilates vessels, sildenafil puts down systolic pressure of the blood. Such vasodilating influence is hazardous in combination with the nitrates’ vasodilating effect. Nitrates are commonly prescribed to patients, who have problems with coronary artery. Those, who simultaneously take these two drugs, are at risk of getting strong hypotension and syncope. Therefore, sildenafil is prohibited to be taken together with nitrates (nitroglycerine such as Nitrolingual, Nitro-Dur patches, etc.).

On the other hand, sildenafil is tolerated quite well in males, suffering from coronary artery condition, if they don’t have severe ischemia and don’t take nitrates.

As sildenafil may contribute to the blood pressure drop, it may be dangerous for individuals with constant hypotension.

cvd and diabetes

Diabetes and Heart Disease – Is There an Interconnection?

Cardiovascular diseases (CVD) is the leading cause of death in the world. Diabetes is also in the top 10 causes of death. Therefore, these diseases require prevention and careful monitoring in case of detection. There is scientific evidence that these two groups of diseases are interrelated, which on the one hand worsens the situation, but on the other hand makes it possible to use the same methods of prevention.

Diabetes and Cardiovascular Diseases:

Diabetes is a chronic disease. Patients with this disease cannot produce insulin or use existing insulin. Insulin is a hormone that is synthesized by the pancreas. It is necessary for the transfer of glucose from the blood into the cells of the body, which due to it receive energy. If glucose is incorrectly transferred and not absorbed by the cells, blood sugar increases, resulting in a number of harmful effects.

Despite the fact that diabetes is actually an incurable disease, living with it can be bearable.

CVD is a complex concept that reflects many diseases of the heart and blood vessels. According to the classification of the World Health Organization, this group includes the following diseases:

  • hypertension (high blood pressure);
  • ischemic heart disease (chronic – periodic angina attacks, acute – myocardial infarction);
  • stroke (a circulatory disorder in the brain);
  • peripheral vascular diseases (reduction or blockage of limb vessels);
  • heart failure (decompensated myocardial dysfunction);
  • rheumatic heart disease;
  • congenital heart defects (eg, hypoplasia, ventricular septal defect, tetralogy of Fallot, transposition of the great vessels, and Ebstein’s anomaly);
  • cardiomyopathy (damage to the heart muscle of unknown etiology).
diabetes and heart disease

Diabetes and Cardiovascular Illnesses: a Correlation

According to “A Statement for Healthcare Professionals From the American Heart Association” (by Scott M. Grundy , Ivor J. Benjamin et al, 1999), there is a scientific rationale to classify diabetes as a major risk factor for cardiovascular diseases. Moreover, from the point of view of medicine it can be treated as this type of disease. Turning back to its role as a risky factor, the doctors noted that diabetes contributes to the development of atherosclerotic coronary heart disease (CHD) due to chronic hyperglycemia. Then, mortality from stroke increases almost three-fold in comparison with patients who don’t suffer from diabetes. Also, persons with type II diabetes often have insulin resistance. This condition was linked to the risks of diabetes occurrence. Moreover, high blood sugar level is known to be damaging for vessels.

Vice versa, CVD may contribute to the worsening of diabetes. For instance, hypertension plays in favor of diabetic neuropathy, a nerve damage that affects a range of nerves in the bodies of some diabetics.

In addition, several predisposing factors are common for these dangerous illnesses. These include the following ones:

  • obesity (overweight);
  • physical inactivity (sedentary lifestyle);
  • hereditary factors;
  • sex (gender);
  • advancing age.
diabetes diet

How to Prevent Diabetes and Cardiovascular Diseases?

Well, there is a firmly established interconnection between diabetes mellitus and heart diseases. This means that methods of their prophylaxis may be similar or even identical. Let’s analyze recommendations provided by healthcare professionals:

  • reduce the consumption of sugary products (sweets, jellies, cakes, donuts, etc.);
  • reduce consumption of products made from white processed flour (white pasta, white bread, breakfast cereals);
  • create a healthy diet that includes fruit and vegetables (at least 400 g) per day;
  • try to eat at approximately regular intervals to avoid overeating;
  • go in for sports (join a gym, go to the swimming pool), or at least do simple physical exercises, and walk more;
  • if you are overweight, lose weight (it is better to do it slowly, losing about 2 pounds a week, rapid slimming may be non-safe);
  • give up bad habits (smoking, excessive alcohol consumption);
  • monitor your blood cholesterol level by taking blood tests regularly.

Any disease is easier to prevent than to cure. Therefore, a healthy lifestyle should be your number 1 rule of living.

life with diabetes

Life with Diabetes: It Can Definitely Be Fulfilling with Proper Treatment

Prevalence of diabetes mellitus in high worldwide. The quantity of people suffering from diabetes has increased significantly from 108 mln in 1980 to 422 mln in 2014. It is expected that this number will reach 700 mln in 2025 (Tawanda Chivese, Werfalli Mahmoud, South Africa & USA, 2016).

What is Diabetes? Why Does It Develop?

Diabetes is a disease of a chronic nature. It strikes the human body when the pancreas loses the ability to synthesize a sufficient amount of insulin.

Insulin is a pancreatic protein hormone that provides regulation of carbohydrate metabolism in the body, by the way, bodybuilders use it to gain weight.

Insulin affects blood sugar levels. If diabetes remains uncontrolled, the glucose level rises, hyperglycemia develops, which over time leads to damage to internal organs and systems.

There are two types of diabetes. Type 1 is characterized by poor insulin production. Most likely, this unhealthiness is of a genetic nature and cannot be prevented.

Type 2 disease is different when the body uses insulin incorrectly / inefficiently. Usually this malady is acquired, it develops due to factors such as a sedentary lifestyle and overweight. It develops gradually over a long period of time, unlike type 1 diabetes. Therefore, often some symptoms go unnoticed and the body receives some damage, for example, a man can develop erectile dysfunction (ED). There is good news: this form of the disease can be prevented.

Read more about diabetes-induced erectile dysfunction, how to prevent and treat it.

Medicamentous Treatment of the Disease

Type II of the illness may be treated with the following drugs:

  • Metformin (Glucophage, Glumetza, Obimet, Dianben and other brand names), which lowers glucose formation in the liver and enhances insulin sensitivity.
  • Sulfonylureas. This cohort of medicaments includes glyburide (Glibenclamide), glipizide (Glucotrol, Glucotrol XL, Minodiab), and glimepiride (Glimepiride Accord Healthcare, Vedapride, Ziglim).
  • Meglitinides. They are similar to sulfonylureas but provide faster effect and have shorter half-life. Meglitinide group include repaglinide and nateglinide.
  • Thiazolidinediones. They boost insulin sensitiveness. Thiazolidinedione class comprises rosiglitazone (Avandia, Diaben, Diazan) and pioglitazone (Actos, Apo-Pioglitazone, Glidipion, etc.).
  • Insulin. It may be long-acting (insulin glargine Lantus) and rapid-acting (Humalog by Eli Lilly).
  • Other meds. These include SGLT2 inhibitors, GLP-1 receptor agonists, and DPP-4 inhibitors.

People suffering from type 1 diabetes need lifelong insulin therapy.

A lot of the abovementioned meds (their generic versions) can be easily bought in the Canadian Health Care Mall.

Living with Diabetes

Is it possible to live a full life with diabetes? Doctors believe that this is certainly possible if you (and your relatives) take care of yourself. You have to eat in time, administer insulin correctly (or take antidiabetic pills in time), select an adequate dose, monitor blood sugar, etc. Exercise every day for at least 30 minutes. You should also limit stressful situations, because they are associated with glucose fluctuations in the blood and negative effects on the body, for example, if your work is stressful and you can do nothing about it, you should change the job (employment). Of course, life with diabetes is more difficult than the life of a healthy person. It is associated with constant obstacles and difficulties, but it can be full.

In order to lead the same way of life that was familiar to a patient before the disease, he / she and his / her family members need to learn the basic rules of self-control.

If you learn how to independently assess changes in your condition, regularly determine the level of glucose in the blood, you can achieve very good results.

Although you can live a full life, there are some limitations. The following habits, which may have a negative effect on the body of a diabetic person, should be abandoned:

  • drinking alcohol in high dosages;
  • snacks between the main (carefully planned) meals;
  • skipping scheduled meals;
  • smoking tobacco;
  • use of narcotic drugs.

The abovementioned recommendations mostly concern both diabetics and healthy people. They help to maintain the health of the body and prevent the development of various dangerous diseases (not only diabetes, but also cardiovascular illnesses, gastrointestinal tract conditions, etc.).