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Viagra, Antibiotics, and Other Meds that Were Discovered Accidentally

Many medicines were invented during a long and painstaking work aimed at the development of a specific substance that must treat a certain disease. But some medicines or their effects were discovered quite by accident.

Discovery of Sildenafil’s Anti-ED Effect

This entertaining story is well-known. In the early 1990s, Pfizer scientists worked on a medicine for cardiovascular disease, but at the stage of clinical trials it was found that the drug did not provide a substantial cardiac action, but it had an unexpected and very interesting “side effect“. Some participants did not want to return the pills. It turned out that they had a significantly improved penile erection.

After a lot of new research and safety checks in 1998, blue pills were released to the market, thus giving men and their partners a chance to renew their sexual relations. Viagra caused a real sensation in the market of anti-ED medications, because earlier there had not been such effective and easy-to-use tablets.

By the way, the Nobel Prize (a parody of the Nobel Prize), which is awarded annually to scientists for the most useless research, was awarded in 2007 to three Argentine researchers who found that sildenafil helped hamsters recover better after jet-lag. Jet-lag and Viagra information here. Read more

myths and truths

11 Myths and Truths About Condoms

Rubber condoms were invented in the XIXth century with latex ones following shortly in the early XXth century. The condom provides perfect protection (>90%) against gonorrhea, HIV, and hepatitis B.

However, according to recent studies, only 1/3 of young people in the USA used condom during their last sex. Topic about prolong sex with medication – Dapoxetine review.

This situation is partly due to some myths and misconceptions existing amongst the people. Well, it’s time to dispel the stereotypes associated with condoms.

  1. Condoms Have a Scent of Latex”

It’s not surprising, is it? Condoms are made of rubber hence they have the smell of rubber. You know, there are many other things that may smell during sex, so the condoms would not be a problem. If you hate that smell, you have options to choose from, for instance, Durex flavored condoms or completely odorless Naked condoms that are made of plastic.

  1. Foreplay Is Bad With Condoms”

This is a common misconception. But in order not to spoil the preliminary caresses, you just need to be able to quickly put on a condom. In fact, you only need about 20 seconds. Use condoms more often and eventually this problem will go away by itself.

  1. Condoms Decrease Sexual Pleasure”

According to the research by Mary E. Randolph et al. (2007), a lot of people believe that condoms badly affect sexual pleasure and many males who think so are less likely to use them. In fact, the difference is nonsignificant. Those suffering from allergy to lubricants and latex may feel bigger difference, however, they, again, can choose lubricant-free options made of plastic.

  1. Condoms Are the Man’s Responsibility”

Some people (heterosexual ones) believe that a man should purchase condoms and carry them around if he is planning to have sex. Are they kidding us?

Really, no matter who has purchased condoms if someone gets infected. The decisions that prevent diseases are a matter of personal responsibility. If you suggest having sex with a condom, it means you appreciate your and your partner’s health.

Moreover, there are female condoms (also called femidoms or internal condoms) – a big condom variation that is inserted in the vagina.

  1. Condoms Cost Too Much”

There are schools that distribute condoms for free among adolescents and young people aged 13 to 25. For older folks, there are many other ways to get those at a low price or even free of charge. Some foundations and organizations specializing in sexual health do that.

Agree, condom is a cheap thing in comparison with potential health problem that can lead to huge money-wasting.

  1. Condoms Provide Full Protection Against Diseases”

Condoms efficiently prevent from sexually transmitted diseases & pregnancy, but they do not guarantee 100% protection. One can get infected with both herpetic infection or genital warts in the area that is not covered by the sheath. Genital warts are small soft growths caused by human papillomavirus (HPV) and occurring on genitals. They are generally safe for males (but they can rarely lead to penis cancer); female persons are more vulnerable to complications of genital warts. Some types of human papillomavirus cause vulva & cervix cancer.

In addition, the warts may cause physical discomfort during sexual act. Similar to genital warts, herpes might disappear by itself, however, it remains in the blood and its breakouts are painful and unpleasant.

  1. Two Condoms Ensure More Protection”

This statement may seem reasonable, but that’s not true. “Doubled” condoms don’t maximize the protection. Quite the opposite, this practice can decrease effectiveness of condoms. When you use two contraception sheaths simultaneously, friction occurs between them, which increases the possibility of condom breakage.

Therefore, it is not recommended to use 2 condoms at time, which applies not only to male condoms but also to male plus female condoms.

  1. Condoms Break Easily”

Condoms have perfect stretchability, and many of them can be stretched up to 1 meter. Condom breakage cases are usually associated with improper rolling on the penis. When you are putting on a condom, there should be no air in it. Also, gaps can be caused by sharp woman’s nails. A lubricant based on oil can make a condom less resistant, therefore it is recommended to use only silicone- and water-based lubes. If you follow the instructions and do everything right, condoms are unlikely to break. You should also store them in cool & dark place so that they will “work” longer.

  1. You Should be Full-Aged to Buy Condoms”

There are no age restrictions to purchase condoms (unlike alcohol and cigarettes). Furthermore, in some US states, condoms are distributed among teenagers under 15 so that they learn more about contraceptive means and use them properly when the moment comes.

  1. It Is So Awkward to Buy Condoms”

You don’t have to worry about this. According to statistical data, 450,000,000 contraception sheaths are sold in the US each year. It may be embarrassing to purchase the condom for the 1st time, but agree, it is much more embarrassing to tell someone about the caught sexual infection. If you still have problems with that, you can order condoms online with delivery in a non-descript packaging.

  1. It’s Difficult to Catch an Infection”

In fact, it is very easy to catch an infection if your partner is a carrier of a sex transmitted disease. Some STDs manifest themselves after a long time so a person can think that he / she is healthy but it is not. HIV can appear in a few weeks in the form of fever, swollen lymph nodes, and other unpleasant symptoms. Then they go away, but after a few years new symptoms of immunodeficiency come back with renewed vigor. HIV is gradually transformed into AIDS.

We do not think we should explain the danger of AIDS, as this is well-known information. Chlamydia can be asymptomatic, but it can lead to miscarriage in women.

Therefore, do not risk your health if you do not have a regular and healthy partner. Clear your mind of myths and use condoms.

explanation_of_ith

Explanation of Itch

General Information

Itch is an specific unpleasant feeling causing a demand to scratch the damaged area. It is not an independent disease but only a symptom which witnesses about derm helminthiasis, central nervous system and inner organs damages.

Types

According to the spread there are two types of itch that’s local itch and pruritus generalisatus. Local itch can be considered to be head skin itch, on wrist and hand skin. Head skin itch is a subjective sensation, it is difficult to estimate its intensity.

It can be expressed and imperceptible, according to the time span it may be constant and temporary.

Mechanism

The mechanism of skin itch development isn’t so simple as can seem at first sight. In its basis a chain from consecutive nervous and antibody responses in skin, and the set of the most different factors can provoke the appearance of itch.

It is known that pain and itch are perceived by the same receptors in skin.

Biologically active substances released by leukocytes and other cells of the immune system play the main role in itch appearance. Other words itch may be called inflammatory mediators.

Causes

Local reasons of skin itch are:

The reasons of pruritus generalisatus are the following:

Treatment

Itch brings so unpleasant feelings that people are eager to get rid of it as faster as possible that’s why you should begin treatment as fast as you can. For achieving the best results you may check out the website of Canadian Health and Care mall. It is the Internet supplier of well-qualified preparations and besides it ships itch drugs internationally.

Search Results for “Itch” medications – by link.

Before implementing recommendations about skin itch treatment, it is necessary to exclude factors which cause its excessive dryness namely washing hands with hot water, wearing synthetic clothes, emotional experiences, intake of some drugs. Only after excluding all these events you may identify whether the itch is a real disease and you may find the treatment to it.

At infectious and parasitic skin damages it is necessary to influence the reason causing a skin itch directly. These are local antiseptics and antibiotics, means from true lice and helminths. At an allergic skin itch origin antihistamines, as for the use inside, and external forms in the form of lotion, ointments, gel may be applied. The doctor can appoint glucocorticoids for local applying to a short period.

All these itch medications you may find on the My Canadian Online Pharmacy – https://mycanadianhealthcaremall.com/. Do not waste time and look for this website immediately.

disease management

Trends in Clinical Management Cost-Containment Strategies

Within both private and public insurance programs, there are trends in strategies that attempt to optimize health outcomes while containing costs. Private sector initiatives dominate; however, many of these same strategies have been implemented within Medicaid managed care and SCHIP programs in various ways.

Pay for Performance

The new shift to a consumer-driven focus, the increasing availability of quality performance data, and a renewed focus on achieving measurable quality improvement have spurred a renewed focus on using financial incentives to reward providers delivering higher quality care. Incentive arrangements target a mix of process and structural measures, with a smaller role for patient satisfaction measures. One study identified 37 pay-for-performance initiatives nationally. Current initiatives are varied in focus, ranging from programs centered around process measures, such as the Health Plan Employer Data and Information Set diabetes or mammogram screening, to patient experience measures, clinical outcome measures, such as complications or mortality, or structural measures, such as the Leapfrog measures for hospitals or information systems to track chronically ill patients. The three largest pay-for-performance initiatives are the Integrated Healthcare Association (IHA) initiative, the Bridges to Excellence program, and the Leapfrog Group. IHA includes seven large plans that represent 60% of the California market. Bridges to Excellence is a multilateral effort that is backed by group of large employers to offer financial incentives for physicians to improve health-care quality in several target markets (ie, Boston, Cincinnati/Louisville, and Albany/ Schenectady). IHA and Bridges to Excellence are part of the $8.8 million Rewarding Results program, which is jointly funded by The Robert Wood Johnson Foundation and the California Healthcare Foundation, with additional funding from the Commonwealth Fund. The Leapfrog Group is focused on improving patient safety by encouraging participating employers to reward hospitals that implement three selected safety measures (ie, computer physician order entry, evidence-based hospital referral, and ICU physician staffing).

There is some evidence that such incentives are affecting provider performance, Anthem Blue Cross and Blue Shield in New Hampshire, for example, which represents > 40% of the New Hampshire market, provided tiered financial incentives to providers (eg, those ranking in the top 25% of the network for a specific quality measure) based on performance for a number of Health Plan Employer Data and Information Set quality measures. Bonus payments to individual physicians ranged from $1,183 to > $15,000. Significant improvements in quality performance were realized. Immunization rates nearly tripled in 1 year, from 21% in 1991 to 58.5% in 2000, although a systematic study of the impact of pay for performance on health outcomes has yet to be conducted.

Plans are also beginning to use patient incentives, particularly within employer-sponsored health plans. Since 1996, the percentage of companies offering consumers financial incentive/disincentive programs increased from 34 to 42%. By 2004, 10% of companies provided incentives for at-risk individuals to participate in condition-management programs or to comply with recommended therapies, with a heavy focus on prescription drugs.

Disease Management

Another major strategy to improve the quality of care while controlling costs has been disease-management (DM) programs. In the 1990s, DM programs emerged as a population-based approach. In population-based programs,

“practitioners accept responsibility for the health outcomes and utilization of all members of a targeted group [such as health plan enrollees with a triggering diagnosis]

and not just individuals who seek treatment during a given period to identify persons at risk, to intervene with specific programs of care, and to measure clinical and other outcomes, particularly for patients with chronic conditions in which patient self-management plays a large role.

The most popular consumer incentive is reduced or waived copayments for mail-order prescriptions (17%). Other popular approaches include reducing costs for drugs to treat targeted conditions (8%), supporting upfront incentives for high-risk employees (4%), and supporting lower annual premiums to participants (4%). In 2005, of the 83% of companies that used DM programs, 30% of these companies offered incentives to encourage employee participation in wellness programs. DM or care-management programs have also begun to proliferate among Medicaid programs. In FY 2005, the number of states that developed new or expanded DM programs totaled 26. For FY 2006, 25 states reported plans to either pilot a new program or expand existing pro-grams.

Many states have chosen pharmaceutical management as their population-based DM focus due to the dramatic increases in prescription drug costs. Others have entered into multiple-disease arrangements with DM organizations. Such programs are largely driven by guaranteed costs savings, with perhaps 20% of financial incentives tied to clinical indicators. States are still experimenting in search of optimal models. North Carolina, for example, started with adding a targeted asthma initiative and later added diabetes on to its primary care case management program, paying primary care physicians an additional increment for disease management.

This program reported success in terms of both clinical indicators and cost.

The Virginia Health Outcomes Partnership, which provided training to physicians in the Medicaid primary care case management program to better manage asthma care saved the state > $659 per physician trained; nevertheless, the state opted to shift to an outsourced population-based DM model that focused on pharmaceutical management because it was simpler and cheaper to administer.
Information Technology and Electronic Health Records

Attention to and investment in information technology (IT) and electronic health records (EHRs) has been increasing in the past few years in both the public and private sectors. For example, Kaiser Permanente committed $1.8 billion to the implementation of its EHR system in 2003. The Veterans Health Administration Computerized Patient Record System was released in 1997 and is now used at > 1,300 sites, while the Department of Defense Composite Health Care System II project, to be implemented at 100 hospitals and 500 clinics, is scheduled for completion by 2006. To date, Medicaid programs have not been central players in the IT phenomenon, although some states are becoming more involved in IT initiatives. A national survey of physician organizations found clinical IT most strongly associated with the use of care-management strategies. An asthma-specific initiative, which followed Medicaid-insured children with asthma in 85 practice sites in five health plans across three states, found IT systems to be the single most deficient area among all processes of care for asthma.

A recent study of health IT adoption among community health centers found that health centers serving the greatest number of poor and uninsured were significantly less likely to have an electronic medical record. Given the importance of health IT capacity in effectively managing patient care, slower health IT adoption among providers that serve disproportionately low-income and minority patients may exacerbate health disparities.

healthcare

My Canadian Pharmacy share about Health and Abundance

The main two folks topics are popular to be discussed concerning two statements “health” and “abundance”. These are two main components of successful life . There are the main points which connect health and abundance. You may have abundance but do not be healthy. And these two statements are difficult to be related. But My Canadian Pharmacy staff are going to look through the main ideas in this connection.

Energy is one of the vital things. You should have energy enough to enjoy the life into the full extent, it doesn’t mean you need just physical energy but mental as well. After you are malnourished and take miserable body’s care, your mind and body can each become worn down more faster than they might envision. In this case we may draw a parallel between health and abundance because if you will take care of yourself including physical and mental health you will receive abundance.

Stress is important in case when you need it to overcome some conditional state or increase your working capacity. But after such a stress you should give to your body rest, try to find the way to relieve. To be sure not to damage your health you are to calculate the stress level, it shouldn’t be too high but too low is not also good.

Find the answers to your questions about stress here: https://mycanadianhealthcaremall.com/canadian-pharmacy-topic-about-stress.html

Longevity is a key element which we are eager to achieve. It becomes inessential when you work hard and earn money but have no time and health to enjoy your abundance. This is the fact you are to measure your health abilities of working hard and spend your money. You may have a happy life only in case of complete harmony of your physical, mental and financial state.

Taking right and regular body care should become like a law like you get used to your job daily, only in this case it will give you the results which are important in its achievements. Little sacrifices and victims may help you to see the result which will not slow to arrive although you should follow your rules. In such a case you will prolong your life and have time to spend your abundance and enjoy the life.