Active Ingredient

Amoxapine

Amoxapine is a medication that belongs to the tricyclic antidepressant class. It is primarily used to manage symptoms of depression.

This medication may be prescribed in various situations where mood improvement is needed.

Written By Douglas C. Goldberg, MD

Reviewed By Philip Schein, MD

Last Updated 28 Nov 2025

Available Amoxapine Brands

Asendin

Strengths 50mg, 100 mg

Amoxapine is commonly used to treat several mental health conditions related to mood disorders.

Amoxapine works by affecting the balance of certain natural chemicals (neurotransmitters) in the brain.

It primarily blocks the reuptake of norepinephrine and serotonin, which helps elevate mood and reduce anxiety.

This mechanism helps improve symptoms of depression and associated mood disorders.

Not everyone experiences side effects with Amoxapine, and many side effects are mild and temporary.

If you experience any serious or persistent symptoms, contact your healthcare provider.

What is Amoxapine used for?

Amoxapine is used to treat major depressive disorder and anxiety associated with depression.

How long does it take for Amoxapine to work?

The effects of Amoxapine may be noticed within a few weeks, but it can vary from person to person.

Can I drink alcohol while taking Amoxapine?

It is advisable to avoid alcohol as it can increase the sedative effects of Amoxapine.

Are there any dietary restrictions while taking Amoxapine?

There are no specific dietary restrictions, but maintaining a healthy diet is recommended.

Can Amoxapine cause weight gain?

Weight gain is a possible side effect of Amoxapine. Discuss any concerns with your doctor.