Active Ingredient

Chlorambucil

Chlorambucil is a medication used to treat certain types of cancer. It belongs to a class of drugs known as alkylating agents.

This medication works by slowing or stopping the growth of cancer cells in the body.

Written By Douglas C. Goldberg, MD

Reviewed By Philip Schein, MD

Last Updated 28 Nov 2025

Available Chlorambucil Brands

Leukeran

Strengths 2mg

Chlorambucil is commonly used to manage and treat various types of cancers. It is prescribed for:

Chlorambucil works by interfering with the DNA of cancer cells, which prevents them from multiplying and growing.

It adds alkyl groups to the DNA, leading to breaks in the DNA strands and ultimately cell death.

This action helps to reduce the number of cancer cells in the body.

Not everyone experiences side effects from Chlorambucil, and many side effects are mild and temporary. Common side effects may include:

If you experience serious or persistent side effects, contact your doctor.

Monitor your blood cell counts regularly as advised by your doctor.
Avoid contact with people who have infections, as Chlorambucil can lower your immune response.
Do not consume alcohol in excess while taking this medication.
Inform your doctor if you experience unusual bleeding or bruising.
Women should use effective contraception to prevent pregnancy during treatment.

Always consult your doctor for personalized medical advice and before making any changes to your treatment plan.

What is Chlorambucil used for?

Chlorambucil is used to treat certain types of cancers, including chronic lymphocytic leukemia and lymphomas.

How does Chlorambucil work?

It works by interfering with the DNA of cancer cells, preventing them from growing and multiplying.

Can I drink alcohol while taking Chlorambucil?

It is advisable to avoid excessive alcohol consumption while on Chlorambucil. Consult your doctor for specific guidance.

What should I do if I miss a dose?

If you miss a dose, contact your healthcare provider for instructions. Do not double up on doses.

Are there any foods I should avoid while taking Chlorambucil?

There are no specific foods to avoid, but maintain a balanced diet and stay hydrated. Discuss any dietary concerns with your doctor.