Active Ingredient

Cyclophosphamide

Cyclophosphamide is a medication used in the treatment of certain types of cancer and autoimmune conditions. It works by interfering with the growth and multiplication of cancer cells.

This medication is typically administered under the guidance of a healthcare professional and is part of a broader treatment plan.

Written By Douglas C. Goldberg, MD

Reviewed By Philip Schein, MD

Last Updated 28 Nov 2025

Available Cyclophosphamide Brands

Cytoxan

Strengths 50mg

Cyclophosphamide Uses

Cyclophosphamide is used for a variety of medical conditions, primarily in oncology and immunology.

Treatment of certain cancers such as lymphoma and leukemia.
Management of breast cancer.
Control of ovarian cancer.
Treatment of multiple myeloma.
Management of certain autoimmune diseases like lupus and rheumatoid arthritis.

How Cyclophosphamide Works

Cyclophosphamide belongs to a class of drugs known as alkylating agents. It works by adding an alkyl group to the DNA of cells.

This action inhibits the replication of cancer cells, slowing or stopping their growth and spread. It can also suppress the immune system, which is beneficial in treating autoimmune diseases.

Common side effects of Cyclophosphamide

Not everyone experiences side effects with Cyclophosphamide, and many side effects are mild and temporary.

Nausea and vomiting
Hair loss
Loss of appetite
Diarrhea
Changes in skin color
Mouth sores
Fatigue

If you experience serious or persistent symptoms, contact your doctor for advice.

Monitor for any unusual symptoms and report them to your healthcare provider.
Avoid alcohol as it can increase certain side effects.
Stay hydrated to help reduce the risk of kidney damage.
Inform your doctor of any other medications you are taking to avoid interactions.
Do not use Cyclophosphamide if you have certain infections without consulting your doctor.

Always discuss your treatment plan and any concerns with your healthcare provider.

Frequently Asked Questions

What does Cyclophosphamide do?

Cyclophosphamide is used to treat certain cancers and autoimmune diseases by interfering with cell growth and modulating the immune system.

How long does it take for Cyclophosphamide to work?

The effects of Cyclophosphamide can vary depending on the condition being treated and individual response. It is important to follow your treatment plan and consult your doctor for specific timelines.

Can I drink alcohol while taking Cyclophosphamide?

It is advisable to avoid alcohol while taking Cyclophosphamide, as it can increase the risk of certain side effects. Consult your doctor for more guidance.

What should I do if I miss a dose of Cyclophosphamide?

If you miss a dose of Cyclophosphamide, contact your healthcare provider for instructions. Do not double up on doses without medical advice.

Are there any food restrictions while taking Cyclophosphamide?

Generally, there are no specific food restrictions, but maintaining a balanced diet and staying hydrated is recommended. Discuss any dietary concerns with your healthcare provider.