Active Ingredient

Dapagliflozin

Dapagliflozin is a medication used to help control blood sugar levels in adults with type 2 diabetes. It is often prescribed when diet and exercise alone are not enough to manage the condition.

This medication can also be used to reduce the risk of certain heart-related complications in people with type 2 diabetes and cardiovascular disease.

Written By Douglas C. Goldberg, MD

Reviewed By Philip Schein, MD

Last Updated 28 Nov 2025

Available Dapagliflozin Brands

Dapasmart

Strengths 5mg, 10mg

Forxiga

Strengths 5 mg, 10mg

Dapagliflozin Uses

Dapagliflozin is primarily used to manage type 2 diabetes and related conditions. It helps improve glycemic control and offers cardiovascular benefits.

Type 2 diabetes management
Reduction of cardiovascular risk in diabetes
Heart failure management
Chronic kidney disease management

How Dapagliflozin Works

Dapagliflozin works by blocking a protein in the kidneys known as sodium-glucose co-transporter 2 (SGLT2). This action prevents the reabsorption of glucose into the blood, allowing it to be excreted in the urine.

By lowering blood sugar levels, this medication helps to improve glycemic control and can also reduce the workload on the heart and kidneys.

Common side effects of Dapagliflozin

Not everyone experiences side effects, and many are mild and temporary. However, it’s important to be aware of them.

Urinary tract infections
Increased urination
Thirst
Genital infections
Dizziness
Back pain
Increased cholesterol levels

If you experience serious or persistent symptoms, contact your doctor for advice.

Monitor your blood sugar levels regularly as advised by your healthcare provider.
Avoid excessive alcohol consumption while taking this medication.
Inform your doctor about any other medications you are taking to avoid interactions.
Stay hydrated, but do not overdo fluid intake.
Do not use this medication if you experience severe kidney problems without consulting your doctor.

Always consult your healthcare professional before making any changes to your treatment plan.

Frequently Asked Questions

What is Dapagliflozin used for?

Dapagliflozin is used to manage type 2 diabetes and reduce cardiovascular risks associated with the condition.

How does Dapagliflozin work?

It works by preventing glucose reabsorption in the kidneys, which helps lower blood sugar levels.

Can Dapagliflozin cause weight loss?

Some patients may experience weight loss as a result of using Dapagliflozin, due to the excretion of glucose.

Is Dapagliflozin safe for everyone?

Dapagliflozin is not suitable for people with certain kidney problems or those on dialysis. Always consult your doctor before use.

Can I take Dapagliflozin with other diabetes medications?

Dapagliflozin can be taken with other diabetes medications, but you should discuss this with your doctor to ensure safety and effectiveness.