Drospirenone

Drospirenone is a synthetic hormone that belongs to the class of medications known as progestins. It is often used in combination with other hormones for various therapeutic purposes.

This ingredient is commonly found in contraceptive formulations and may also be used to address certain hormonal imbalances.

Information about Drospirenone

Drospirenone Uses

Drospirenone is primarily used in combination with other hormones to help manage specific health conditions.

Birth control to prevent pregnancy
Treatment of moderate acne in specific cases
Management of symptoms associated with premenstrual dysphoric disorder (PMDD)
Hormone replacement therapy in postmenopausal women

How Drospirenone Works

Drospirenone works by mimicking the activity of natural progesterone in the body. It helps regulate the menstrual cycle and prevents ovulation, which is the release of an egg from the ovary.

By altering the cervical mucus and the lining of the uterus, it makes it harder for sperm to reach the uterus and for a fertilized egg to attach to the uterus.

Common side effects of Drospirenone

Not everyone experiences side effects with Drospirenone, and many side effects can be mild and temporary.

Nausea
Headache
Breast tenderness
Weight changes
Mood changes
Menstrual irregularities
Abdominal pain

If you experience serious or persistent side effects, it is important to contact your doctor.

CONTENT DETAILS

Written By

Douglas C. Goldberg, MD

Reviewed By

Philip Schein, MD

Last updated

28 Nov 2025 | 03:00 PM (UTC)

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Expert advice for Drospirenone

Monitor for any unusual symptoms and report them to your healthcare provider.
Avoid heavy alcohol consumption while taking this medication.
Inform your doctor about any other medications you are taking to avoid interactions.
Do not use Drospirenone if you have a history of blood clots or certain types of cancer without consulting a doctor.
Seek medical advice if you experience sudden vision changes or severe headaches.

Always consult your doctor for personalized medical advice and before making any changes to your medication regimen.

Frequently Asked Questions

What is Drospirenone used for?

Drospirenone is used in combination with other hormones for birth control, treating acne, and managing premenstrual dysphoric disorder (PMDD).

How does Drospirenone prevent pregnancy?

Drospirenone prevents pregnancy by stopping ovulation and making it harder for sperm to reach the uterus or for a fertilized egg to attach.

Can Drospirenone cause weight gain?

Weight changes can occur with Drospirenone, but not everyone will experience this side effect.

Is it safe to take Drospirenone with other medications?

You should inform your doctor about all medications you are taking to avoid potential interactions.

What should I do if I miss a dose of Drospirenone?

If you miss a dose, follow the instructions provided by your healthcare provider or contact them for advice.