Active Ingredient

Estriol

Estriol is a type of estrogen, a female hormone involved in various bodily functions. It is often used in medical treatments related to hormonal balance.

This hormone is typically utilized in situations where estrogen levels need to be supplemented or balanced.

Written By Douglas C. Goldberg, MD

Reviewed By Philip Schein, MD

Last Updated 28 Nov 2025

Available Estriol Brands

Estriol

Strengths 1 g

Estriol Cream

Strengths 15 gm

Estriol Uses

Estriol is commonly used for conditions related to estrogen deficiency.

Relief of menopausal symptoms
Treatment of vaginal atrophy
Support in certain hormone replacement therapies
Management of specific urinary tract symptoms

How Estriol Works

Estriol works by mimicking the natural estrogen hormone in the body. It binds to estrogen receptors, helping to regulate various functions that rely on estrogen.

This can include maintaining the health of reproductive tissues and alleviating symptoms caused by low estrogen levels.

As an estrogen hormone, it plays a critical role in maintaining the balance of female hormones.

Common side effects of Estriol

Not everyone experiences side effects with estriol, and many are mild and temporary.

Headache
Nausea
Breast tenderness
Vaginal spotting or bleeding
Stomach upset
Dizziness

If you experience serious or persistent symptoms, contact your healthcare provider.

Monitor for any unusual symptoms and report them to your doctor.
Avoid consuming large amounts of alcohol while using estriol.
Inform your doctor about any other medications or supplements you are taking.
Do not use estriol if you have certain medical conditions without consulting a healthcare professional.
Regular check-ups with your doctor are advised to monitor your response to the medication.

Always consult your doctor for personalized medical advice.

Frequently Asked Questions

What is estriol used for?

Estriol is used to manage symptoms of estrogen deficiency, such as menopausal symptoms and vaginal atrophy.

How long does it take for estriol to work?

The onset of effects can vary, but some users may notice improvements in symptoms within a few weeks.

Is estriol safe for long-term use?

The safety of long-term use should be assessed by your doctor, who will consider your individual health needs.

Can estriol interact with other medications?

Yes, estriol may interact with other medications. It’s important to inform your doctor about all the medications you are taking.

Can men use estriol?

Estriol is typically used for conditions related to female hormone balance and is not commonly prescribed for men.