Active Ingredient

Fluconazole

Fluconazole is a medication used to treat fungal infections. It belongs to a class of drugs called antifungal agents, which work by stopping the growth of fungi.

It is commonly prescribed for infections in various parts of the body, including the mouth, throat, and genitals.

Written By Douglas C. Goldberg, MD

Reviewed By Philip Schein, MD

Last Updated 28 Nov 2025

Available Fluconazole Brands

Diflucan

Strengths 50mg, 100mg, 150mg, 200mg, 400mg

Fluconazole Uses

Fluconazole is typically used to manage and treat a variety of fungal infections. It is effective against several types of fungi.

Vaginal yeast infections
Oral thrush
Esophageal candidiasis
Cryptococcal meningitis
Fungal infections in patients with weakened immune systems

How Fluconazole Works

Fluconazole works by interfering with the cell membrane of fungi. It inhibits an enzyme necessary for the fungi to produce ergosterol, a key component of their cell membrane.

Without ergosterol, the cell membrane becomes weak and the fungi are unable to survive.

This action helps to stop the infection from spreading and assists the body’s immune system in clearing the infection.

Common side effects of Fluconazole

Not everyone experiences side effects when taking Fluconazole, and many side effects are mild and temporary.

Headache
Nausea
Stomach pain
Dizziness
Diarrhea
Skin rash

If you experience serious or persistent symptoms, contact your healthcare provider.

Take Fluconazole exactly as prescribed by your healthcare provider.
Avoid consuming alcohol while taking this medication, as it may increase the risk of liver problems.
Inform your doctor about any other medications you are taking to avoid potential interactions.
Do not use Fluconazole if you have a known allergy to it or similar antifungal medications.
Seek medical advice if you experience symptoms such as severe skin rash, yellowing of the skin or eyes, or dark urine.

Always consult your doctor or pharmacist if you have any questions or concerns about using Fluconazole.

Frequently Asked Questions

What is Fluconazole used for?

Fluconazole is used to treat various fungal infections such as vaginal yeast infections, oral thrush, and cryptococcal meningitis.

How long does it take for Fluconazole to work?

The time it takes for Fluconazole to work can vary depending on the type and severity of the infection. Some people may notice improvement within a few days.

Can I drink alcohol while taking Fluconazole?

It is advisable to avoid alcohol while taking Fluconazole as it can increase the risk of liver damage.

Are there any common side effects of Fluconazole?

Common side effects include headache, nausea, stomach pain, and dizziness. These are usually mild and temporary.

Can Fluconazole interact with other medications?

Yes, Fluconazole can interact with other medications. It’s important to inform your healthcare provider about all the medications you are taking.