Active Ingredient

Fludrocortisone

Fludrocortisone is a type of corticosteroid medication used to help balance certain hormones in the body. It is often prescribed to manage conditions where the body does not produce enough of its own corticosteroids.

This medication is typically used in situations involving adrenal insufficiency and other related disorders.

Written By Douglas C. Goldberg, MD

Reviewed By Philip Schein, MD

Last Updated 28 Nov 2025

Available Fludrocortisone Brands

Florinef

Strengths 0.1mg

Fludrocortisone Uses

Fludrocortisone is commonly used to treat conditions related to hormone imbalance.

Addison’s disease
Adrenogenital syndrome
Orthostatic hypotension
Salt-losing adrenogenital syndrome

How Fludrocortisone Works

Fludrocortisone works by mimicking the effects of hormones naturally produced by your adrenal glands. It helps to retain sodium and excrete potassium, which helps to maintain fluid balance and blood pressure.

As a corticosteroid, it plays a role in controlling salt and water balance in the body, which is crucial for normal functioning.

Common side effects of Fludrocortisone

Not everyone experiences side effects with Fludrocortisone, and many side effects are mild and temporary.

Headache
Stomach upset
Dizziness
Increased appetite
Weight gain
Swelling due to fluid retention
Increased blood pressure

If you experience serious or persistent symptoms, contact your doctor promptly.

Frequently Asked Questions

What does Fludrocortisone do?

Fludrocortisone helps to maintain fluid balance and blood pressure by mimicking natural hormones produced by the adrenal glands.

How quickly does Fludrocortisone work?

The effects of Fludrocortisone may start to be noticeable within a few days, but it may take longer for full benefits to be observed.

Can I drink alcohol while taking Fludrocortisone?

It’s best to avoid heavy alcohol consumption while taking Fludrocortisone as it can interfere with the medication’s effectiveness.

Are there any dietary restrictions with Fludrocortisone?

You may need to limit salt intake to avoid fluid retention and increased blood pressure. Consult your doctor for specific dietary advice.

Is Fludrocortisone safe for long-term use?

Long-term use of Fludrocortisone should be monitored by a healthcare professional to manage potential side effects and ensure safety.