Gemfibrozil

Gemfibrozil is a medication that belongs to a class of drugs known as fibrates. It is primarily used to help manage cholesterol levels in the body.

It works by reducing the levels of certain types of fats in the blood, which can help lower the risk of heart disease and other related health issues.

Information about Gemfibrozil

Gemfibrozil Uses

Gemfibrozil is typically used to address specific cholesterol and lipid conditions. It can be particularly helpful in certain situations.

High cholesterol levels
Elevated triglycerides
Prevention of pancreatitis in patients with severe hypertriglyceridemia
Combined hyperlipidemia

How Gemfibrozil Works

Gemfibrozil works by activating a specific receptor in the body known as PPAR-alpha. This activation helps to reduce triglyceride levels and increase good cholesterol (HDL) in the bloodstream.

By altering the breakdown and removal of fats, it helps to improve overall lipid profiles. This can be beneficial in reducing the risk of developing heart disease.

Common side effects of Gemfibrozil

Not everyone experiences side effects from Gemfibrozil, and many are mild and temporary if they do occur.

Stomach upset
Heartburn
Diarrhea
Nausea
Fatigue
Dizziness
Rash

If you experience serious or persistent symptoms, it is important to contact a healthcare professional.

CONTENT DETAILS

Written By

Douglas C. Goldberg, MD

Reviewed By

Philip Schein, MD

Last updated

28 Nov 2025 | 03:00 PM (UTC)

Medicine brands for Gemfibrozil

Lopid
Dosage: 300mg
from $56.007 variant(s)

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Expert advice for Gemfibrozil

Monitor your cholesterol levels regularly while taking Gemfibrozil.
Avoid consuming large amounts of alcohol, as it may increase the risk of liver problems.
Inform your doctor about all medications you are taking to avoid potential interactions.
Do not use Gemfibrozil if you have liver or kidney disease unless advised by a doctor.
Report any unexplained muscle pain or weakness to your doctor immediately.

Always consult your healthcare provider for personalized medical advice.

Frequently Asked Questions

What is Gemfibrozil used for?

Gemfibrozil is used to lower high levels of cholesterol and triglycerides in the blood, which can help reduce the risk of heart disease.

How long does it take for Gemfibrozil to work?

The effects on cholesterol and triglyceride levels can be seen within a few weeks, but it may take longer for full benefits.

Can I take Gemfibrozil with other medications?

It’s important to inform your doctor about all medications you are taking, as Gemfibrozil can interact with certain drugs.

Are there any dietary restrictions while taking Gemfibrozil?

It’s advisable to follow a cholesterol-lowering diet and avoid heavy alcohol consumption while on Gemfibrozil.

What should I do if I miss a dose of Gemfibrozil?

If you miss a dose, take it as soon as you remember unless it’s almost time for your next dose. Do not double up on doses.