Granisetron

Granisetron is a medication that helps prevent nausea and vomiting, often used in medical settings. It is commonly administered to patients undergoing certain treatments that can cause these symptoms.

This medication works by blocking certain receptors in the body that trigger nausea and vomiting, providing relief to patients.

Information about Granisetron

Granisetron Uses

Granisetron is typically used to manage nausea and vomiting in various medical situations.

Prevention of nausea and vomiting caused by chemotherapy.
Prevention of nausea and vomiting after surgery.
Management of nausea and vomiting during radiation therapy.

How Granisetron Works

Granisetron works by blocking the action of serotonin, a natural substance in the body that can cause nausea and vomiting. It specifically targets the 5-HT3 receptors in the brain and gut.

By inhibiting these receptors, Granisetron reduces the likelihood of nausea and vomiting occurring after certain medical treatments.

Common side effects of Granisetron

Not everyone will experience side effects from Granisetron, and many side effects are mild and temporary. However, some common ones include:

Headache
Constipation
Fatigue
Dizziness
Diarrhea
Stomach pain
Insomnia

If you experience serious or persistent side effects, contact your doctor.

CONTENT DETAILS

Written By

Douglas C. Goldberg, MD

Reviewed By

Philip Schein, MD

Last updated

28 Nov 2025 | 03:00 PM (UTC)

Medicine brands for Granisetron

Kytril
Dosage: 1mg, 2mg
from $61.0011 variant(s)

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Expert advice for Granisetron

Monitor for any unusual symptoms and report them to your doctor.
Avoid heavy alcohol consumption while taking this medication.
Inform your healthcare provider about any other medications you are taking to prevent interactions.
Do not use Granisetron if you have a known allergy to it.
Seek medical advice if you experience severe headache, chest pain, or irregular heartbeat.

Always consult your doctor for personalized medical advice.

Frequently Asked Questions

What is Granisetron used for?

Granisetron is used to prevent nausea and vomiting associated with chemotherapy, radiation therapy, and surgery.

How quickly does Granisetron work?

Granisetron usually begins to work shortly after administration, but the exact onset can vary between individuals.

How long does the effect of Granisetron last?

The duration of Granisetron’s effects can vary, but it is designed to provide relief from nausea and vomiting for several hours.

Is Granisetron safe for everyone?

Granisetron is generally safe when used as directed, but it may not be suitable for everyone. Discuss with your doctor if you have any concerns.

Can Granisetron interact with other medications?

Yes, Granisetron can interact with other medications. It’s important to inform your doctor about all the medications you are taking.