Active Ingredient

Hydroxyurea

Hydroxyurea is a medication used to treat certain types of cancer and blood disorders. It helps manage the disease by affecting the growth of cancer cells.

It is often prescribed for patients with chronic conditions to help control symptoms and improve quality of life.

Written By Douglas C. Goldberg, MD

Reviewed By Philip Schein, MD

Last Updated 28 Nov 2025

Available Hydroxyurea Brands

Hydrea

Strengths 500mg

Hydroxyurea Uses

Hydroxyurea is commonly used to treat the following conditions:

Chronic myeloid leukemia (CML)
Polycythemia vera
Essential thrombocythemia
Sickle cell anemia

How Hydroxyurea Works

Hydroxyurea works by interfering with the growth and spread of cancer cells in the body. It belongs to a class of drugs known as antineoplastic agents.

This medication helps reduce the number of abnormal blood cells, allowing the body to function more normally.

It may also help increase fetal hemoglobin levels in sickle cell anemia, which can reduce the frequency of painful crises.

Common side effects of Hydroxyurea

Not everyone experiences side effects with Hydroxyurea, and many are mild and temporary. Common side effects include:

Nausea
Vomiting
Loss of appetite
Diarrhea
Dizziness
Headache

If you experience serious or persistent symptoms, contact your healthcare provider.

Frequently Asked Questions

What is Hydroxyurea used for?

Hydroxyurea is used to treat certain types of cancer such as chronic myeloid leukemia and blood disorders like sickle cell anemia.

How does Hydroxyurea work?

It works by interfering with the growth of cancer cells and increasing fetal hemoglobin levels, which can help manage symptoms.

What are the common side effects of Hydroxyurea?

Common side effects include nausea, vomiting, loss of appetite, diarrhea, dizziness, and headache.

Can I take Hydroxyurea with other medications?

You should inform your doctor about all other medications you are taking to avoid potential interactions.

Is it safe to drink alcohol while taking Hydroxyurea?

It’s best to avoid large amounts of alcohol while taking Hydroxyurea. Consult your doctor for more personalized advice.