Active Ingredient

Ibuprofen

Ibuprofen is a widely used nonsteroidal anti-inflammatory drug (NSAID) that helps reduce pain, inflammation, and fever. It is commonly used to treat a variety of minor aches and pains.

People often take ibuprofen for temporary relief of symptoms such as headaches, muscle pain, or minor arthritis pain.

Written By Douglas C. Goldberg, MD

Reviewed By Philip Schein, MD

Last Updated 28 Nov 2025

Available Ibuprofen Brands

Motrin

Strengths 200 mg, 400mg, 600mg

Nurofen

Strengths 200mg, 400mg, 600mg

Ibuprofen Uses

Ibuprofen is commonly used for its pain-relieving and anti-inflammatory properties. It can help with a variety of conditions.

Relief of mild to moderate pain
Reduction of fever
Management of inflammation in conditions like arthritis
Alleviating menstrual cramps
Reducing pain from minor injuries

How Ibuprofen Works

Ibuprofen works by blocking the production of certain natural substances in your body that cause inflammation. This action helps to reduce swelling, pain, and fever.

It belongs to a class of drugs known as nonsteroidal anti-inflammatory drugs (NSAIDs), which target enzymes involved in the inflammatory process.

Common side effects of Ibuprofen

Not everyone experiences side effects from ibuprofen, and many are mild and temporary. However, some common side effects can occur.

Stomach upset or pain
Nausea
Dizziness
Headache
Heartburn
Rash

If you experience serious or persistent symptoms, contact your healthcare provider.

Avoid using ibuprofen on an empty stomach to reduce the risk of stomach upset.
Do not mix ibuprofen with heavy alcohol consumption as it may increase the risk of stomach bleeding.
Be cautious of potential interactions with other medications; consult your doctor or pharmacist.
Avoid using ibuprofen if you have certain health conditions like severe heart disease or ulcers without medical advice.
Monitor for any unusual symptoms and seek medical attention if necessary.

Always consult your healthcare provider for advice tailored to your health situation.

Frequently Asked Questions

How quickly does ibuprofen work?

Ibuprofen typically starts to work within 30 to 60 minutes after taking it.

How long do the effects of ibuprofen last?

The effects of ibuprofen generally last for 4 to 8 hours, depending on the dose and individual response.

Can I take ibuprofen with other medications?

Ibuprofen can interact with other medications. It’s important to check with your healthcare provider before combining it with other treatments.

Is ibuprofen safe for long-term use?

Long-term use of ibuprofen should be monitored by a healthcare provider due to potential risks, such as gastrointestinal issues or cardiovascular concerns.

Can ibuprofen cause allergic reactions?

Some people may experience allergic reactions to ibuprofen, including rash, itching, or swelling. Seek medical help if you notice any severe reactions.