Isosorbide

Isosorbide is a medication used to help manage certain heart conditions. It is often prescribed to prevent chest pain (angina) by improving blood flow to the heart.

This medication is typically used in situations where patients need to alleviate symptoms related to heart disease.

Information about Isosorbide

Isosorbide Uses

Isosorbide is commonly used for the prevention of certain heart-related issues. It helps reduce the frequency of chest pain episodes.

Prevention of angina pectoris (chest pain)
Management of heart failure symptoms
Improving exercise tolerance in heart conditions
Reducing strain on the heart

How Isosorbide Works

Isosorbide works by relaxing and widening blood vessels, which helps to increase blood flow to the heart. This action reduces the heart’s workload and the oxygen demand of the heart muscle.

By doing so, it helps to prevent episodes of angina and improve the heart’s efficiency.

As a nitrate vasodilator, it targets the smooth muscles in the blood vessel walls, leading to vasodilation.

Common side effects of Isosorbide

Not everyone experiences side effects with Isosorbide, and many of them are mild and temporary. However, some common side effects include:

Headache
Dizziness
Nausea
Flushing
Low blood pressure
Fatigue
Lightheadedness

If you experience serious or persistent side effects, it is important to contact your healthcare provider.

CONTENT DETAILS

Written By

Douglas C. Goldberg, MD

Reviewed By

Philip Schein, MD

Last updated

28 Nov 2025 | 03:00 PM (UTC)

Medicine brands for Isosorbide

Imdur
Dosage: 20mg, 60mg
from $34.008 variant(s)

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Expert advice for Isosorbide

Monitor your symptoms and report any unusual changes to your doctor.
Avoid consuming large amounts of alcohol while taking this medication.
Do not stop taking Isosorbide suddenly without consulting your doctor.
Be cautious when standing up quickly, as this may cause dizziness.
Inform your healthcare provider about any other medications you are taking to avoid potential interactions.

Always consult your doctor for personalized medical advice.

Frequently Asked Questions

What is Isosorbide used for?

Isosorbide is used to prevent chest pain (angina) and manage symptoms of heart failure by improving blood flow to the heart.

How does Isosorbide work?

Isosorbide works by relaxing and widening blood vessels, which helps increase blood flow to the heart and reduce its workload.

Can I take Isosorbide with other medications?

You should inform your doctor about all medications you are taking, as Isosorbide can interact with other drugs, potentially affecting how they work.

What should I do if I miss a dose of Isosorbide?

If you miss a dose, take it as soon as you remember unless it is almost time for your next dose. Do not double the dose to catch up.

Are there any activities I should avoid while taking Isosorbide?

Be cautious with activities that require alertness, such as driving, as Isosorbide can cause dizziness or lightheadedness.