Active Ingredient

Levothyroxine Sodium

Levothyroxine Sodium is a medication used to treat thyroid-related conditions. It helps replace or supplement the natural hormone produced by the thyroid gland.

This medication is commonly prescribed for individuals with underactive thyroid, also known as hypothyroidism, and other related conditions.

Written By Douglas C. Goldberg, MD

Reviewed By Philip Schein, MD

Last Updated 28 Nov 2025

Available Levothyroxine Sodium Brands

Levothroid

Strengths 25 mcg, 50 mcg, 75 mcg, 100 mcg, 112 mcg, 125 mcg, 200 mcg

Levothyroxine Sodium Uses

Levothyroxine Sodium is primarily used to manage thyroid hormone levels in the body. It is prescribed for various thyroid-related conditions.

Treatment of hypothyroidism
Management of goiter
Thyroid cancer treatment support
Thyroid hormone replacement therapy
Prevention of thyroid enlargement

How Levothyroxine Sodium Works

Levothyroxine Sodium works by supplementing or replacing the thyroid hormone that the thyroid gland is unable to produce in sufficient quantities.

This hormone is crucial for maintaining normal metabolism, energy levels, and overall body function.

By restoring normal hormone levels, it helps alleviate the symptoms associated with thyroid hormone deficiency.

Common side effects of Levothyroxine Sodium

Not everyone experiences side effects from Levothyroxine Sodium, and many are mild and temporary. However, some people may experience certain side effects.

Headache
Insomnia
Increased appetite
Weight loss
Nervousness
Diarrhea
Heat intolerance

If you experience serious or persistent symptoms, it is important to contact your doctor.

Take Levothyroxine Sodium on an empty stomach for better absorption.
Avoid consuming high-fiber foods close to taking this medication as it may affect absorption.
Inform your doctor about any other medications you are taking to avoid potential interactions.
Monitor your symptoms and report any unusual changes to your healthcare provider.
Avoid excessive intake of soy products as they may interfere with the medication’s effectiveness.

Always consult your doctor for personalized medical advice and regular monitoring of your thyroid levels.

Frequently Asked Questions

What does Levothyroxine Sodium do?

Levothyroxine Sodium helps replace or supplement the thyroid hormone in the body, which is essential for normal metabolism and energy levels.

How long does it take for Levothyroxine Sodium to work?

It may take several weeks to notice an improvement in symptoms as the body adjusts to the medication. Regular monitoring by your doctor is important.

Can I take Levothyroxine Sodium with food?

It is generally recommended to take Levothyroxine Sodium on an empty stomach for optimal absorption. Consult your doctor for specific instructions.

Are there any interactions with Levothyroxine Sodium?

Yes, certain medications and foods can affect how Levothyroxine Sodium works. Discuss all your current medications and dietary habits with your doctor.

Is it safe to consume alcohol while taking Levothyroxine Sodium?

While moderate alcohol consumption may not directly affect the medication, it’s best to consult your doctor for advice tailored to your health condition.