Mefenamic Acid

Mefenamic Acid is a medication that belongs to the class of non-steroidal anti-inflammatory drugs (NSAIDs). It is commonly used to relieve pain and reduce inflammation in various conditions.

This medication is often considered for short-term treatment of mild to moderate pain and is sometimes used in specific types of pain related to menstruation.

Information about Mefenamic Acid

Mefenamic Acid Uses

Mefenamic Acid is typically used to manage pain and inflammation in several conditions. It is particularly helpful in situations requiring short-term relief.

Pain relief during menstruation (dysmenorrhea)
Relief from mild to moderate pain
Inflammatory conditions
Muscle pain
Dental pain

How Mefenamic Acid Works

Mefenamic Acid works by blocking the production of certain natural substances in the body that cause inflammation and pain. It inhibits the enzyme cyclooxygenase (COX), which plays a role in the formation of prostaglandins.

By reducing the levels of prostaglandins, Mefenamic Acid helps decrease inflammation and alleviate pain.

Common side effects of Mefenamic Acid

Not everyone experiences side effects when taking Mefenamic Acid, and many are mild and temporary. However, it is important to be aware of possible reactions.

Stomach upset
Nausea
Dizziness
Headache
Diarrhea
Heartburn
Rash

If you experience severe or persistent side effects, contact your doctor.

CONTENT DETAILS

Written By

Douglas C. Goldberg, MD

Reviewed By

Philip Schein, MD

Last updated

28 Nov 2025 | 03:00 PM (UTC)

Medicine brands for Mefenamic Acid

Ponstel
Dosage: 250mg, 500mg
from $33.0011 variant(s)

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Expert advice for Mefenamic Acid

Avoid taking Mefenamic Acid on an empty stomach to reduce the risk of stomach upset.
Limit alcohol consumption while using this medication to prevent increased risk of stomach bleeding.
Be cautious if you have a history of gastrointestinal issues, as this medication may aggravate them.
Inform your doctor of all other medications you are taking to avoid potential interactions.
Do not use Mefenamic Acid if you have known allergies to NSAIDs.

Always consult your doctor or healthcare provider for advice tailored to your health condition.

Frequently Asked Questions

What is Mefenamic Acid used for?

Mefenamic Acid is used to relieve pain and inflammation, particularly in conditions like menstrual pain and mild to moderate pain from various causes.

How quickly does Mefenamic Acid work?

Mefenamic Acid typically starts working within a few hours of taking it, providing relief from pain and inflammation.

Can I take Mefenamic Acid with other medications?

It’s important to consult your doctor before combining Mefenamic Acid with other medications to avoid potential interactions.

Is it safe to use Mefenamic Acid long-term?

Mefenamic Acid is generally intended for short-term use. Long-term use should be discussed with your healthcare provider.

What should I do if I miss a dose of Mefenamic Acid?

If you miss a dose, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double up to catch up.