Active Ingredient

Mirtazapine

Mirtazapine is a medication primarily used to manage symptoms of depression. It helps improve mood and feelings of well-being.

This medication is often prescribed to adults experiencing major depressive disorder or related conditions.

Written By Douglas C. Goldberg, MD

Reviewed By Philip Schein, MD

Last Updated 28 Nov 2025

Available Mirtazapine Brands

Remeron

Strengths 7.5 mg, 15 mg, 30mg

Mirtazapine Uses

Mirtazapine is commonly used to treat mental health conditions related to mood disturbances.

Major depressive disorder
Anxiety associated with depression
Insomnia linked to depression
Appetite stimulation

How Mirtazapine Works

Mirtazapine works by balancing neurotransmitters in the brain, specifically norepinephrine and serotonin. These chemicals are important for mood regulation.

By enhancing the effects of these neurotransmitters, Mirtazapine can help improve mood and relieve symptoms of depression.

It belongs to a class of drugs known as tetracyclic antidepressants.

Common side effects of Mirtazapine

While not everyone experiences side effects, some people may notice mild and temporary reactions to Mirtazapine.

Drowsiness
Increased appetite
Weight gain
Dry mouth
Dizziness
Constipation
Fatigue

If you experience any severe or persistent symptoms, it’s important to contact your healthcare provider.

Avoid driving or operating heavy machinery until you know how Mirtazapine affects you.
Limit or avoid alcohol while taking this medication.
Inform your doctor about any other medications you are taking to prevent interactions.
Report any sudden mood changes or thoughts of self-harm to your healthcare provider immediately.
Do not stop taking Mirtazapine abruptly without consulting your doctor.

Always consult your healthcare provider for personalized medical advice.

Frequently Asked Questions

How long does it take for Mirtazapine to work?

Mirtazapine may start to improve sleep and appetite within the first week, but full effects on mood may take a few weeks.

Can Mirtazapine cause weight gain?

Yes, weight gain is a common side effect of Mirtazapine due to increased appetite.

Is it safe to drink alcohol while taking Mirtazapine?

It is advisable to avoid alcohol as it can increase drowsiness and dizziness.

Can Mirtazapine be used for anxiety?

Mirtazapine may help with anxiety symptoms, especially when they are associated with depression.

What should I do if I miss a dose of Mirtazapine?

If you miss a dose, take it as soon as you remember unless it’s close to the time of your next dose. Do not double the dose.