Active Ingredient

Mupirocin

Mupirocin is a topical antibiotic used to treat certain skin infections. It works by stopping the growth of bacteria on the skin.

This medication is often prescribed for infections like impetigo and is applied directly to the affected area.

Written By Douglas C. Goldberg, MD

Reviewed By Philip Schein, MD

Last Updated 28 Nov 2025

Available Mupirocin Brands

Bactroban Ointment 5g

Strengths 20mg

Mupirocin Uses

Mupirocin is primarily used to treat bacterial skin infections. It helps clear up infections and prevent the spread of bacteria.

Treatment of impetigo
Infected cuts or wounds
Folliculitis
Secondary skin infections

How Mupirocin Works

Mupirocin works by inhibiting the bacterial enzyme isoleucyl-tRNA synthetase. This action prevents bacteria from synthesizing proteins essential for their growth.

As a result, the bacteria cannot multiply, and the infection is controlled and eventually cleared.

Common side effects of Mupirocin

While many people using Mupirocin do not experience significant side effects, some may encounter mild and temporary reactions.

Burning sensation at the application site
Itching
Redness
Stinging
Dry skin
Rash

If you experience serious or persistent symptoms, contact your healthcare provider.

Apply Mupirocin only to the affected area as directed by your healthcare provider.
Avoid using other skin products on the treated area unless advised by a doctor.
Do not cover the treated area with bandages or dressings unless instructed.
If irritation or allergic reaction occurs, discontinue use and seek medical advice.
Wash your hands before and after applying the medication.

Always consult your healthcare provider for personalized advice and guidance.

Frequently Asked Questions

What does Mupirocin treat?

Mupirocin is used to treat certain bacterial skin infections, including impetigo and infected wounds.

How quickly does Mupirocin work?

Improvement in symptoms is often seen within a few days, but it is important to complete the full course as prescribed.

Can Mupirocin be used on all skin types?

Mupirocin is generally safe for most skin types, but it should be used with caution on sensitive or damaged skin.

Are there any interactions with Mupirocin?

Mupirocin is a topical medication with minimal systemic absorption, but it’s important to inform your doctor about all other medications you are using.

Is it safe to use Mupirocin during pregnancy?

Consult your healthcare provider to discuss the potential risks and benefits of using Mupirocin during pregnancy.