Active Ingredient

Naproxen

Naproxen is a type of medication known as a nonsteroidal anti-inflammatory drug (NSAID). It is commonly used to relieve pain and reduce inflammation in various conditions.

It can be helpful for managing symptoms of arthritis, muscle aches, and other similar conditions. Naproxen is available in different forms, including tablets and capsules.

Written By Douglas C. Goldberg, MD

Reviewed By Philip Schein, MD

Last Updated 28 Nov 2025

Available Naproxen Brands

Aleve

Strengths 250mg, 500mg

Naprosyn

Strengths 250mg, 500mg

Naproxen Uses

Naproxen is used to alleviate pain and inflammation associated with various conditions. It is often recommended for:

Arthritis
Muscle pain
Back pain
Menstrual cramps
Gout attacks

How Naproxen Works

Naproxen works by blocking the production of certain natural substances in the body that cause inflammation and pain. This action helps to reduce swelling and alleviate discomfort.

As an NSAID, it inhibits enzymes called cyclooxygenases (COX-1 and COX-2), which play a role in the inflammatory process.

Common side effects of Naproxen

Not everyone experiences side effects from Naproxen, and many are mild and temporary. Common side effects include:

Stomach upset
Heartburn
Dizziness
Headache
Nausea
Constipation

If you experience serious or persistent symptoms, contact your doctor for advice.

Take Naproxen with food or milk to minimize stomach upset.
Avoid consuming heavy amounts of alcohol while taking this medication.
Inform your doctor about any other medications you are taking to avoid interactions.
Do not take Naproxen if you have a history of allergic reactions to NSAIDs.
Seek medical attention if you experience symptoms like chest pain, weakness, or slurred speech.

Always consult your doctor before starting or stopping any medication.

Frequently Asked Questions

What is Naproxen used for?

Naproxen is used to relieve pain and inflammation associated with conditions like arthritis, muscle pain, and menstrual cramps.

How long does it take for Naproxen to work?

Naproxen typically begins to work within a few hours, but the full effect may take longer depending on the condition being treated.

Is Naproxen safe for long-term use?

Naproxen can be safe for long-term use under a doctor’s supervision, but it is important to monitor for any side effects.

Can I take Naproxen with other pain relievers?

You should consult your doctor before combining Naproxen with other pain relievers to avoid potential interactions.

What should I do if I miss a dose of Naproxen?

If you miss a dose of Naproxen, take it as soon as you remember unless it is almost time for your next dose.