Active Ingredient

Nicotinamide

Nicotinamide is a form of vitamin B3, an essential nutrient that plays a crucial role in energy metabolism and cellular repair. It is commonly used to address vitamin B3 deficiencies and support overall skin health.

Nicotinamide may be recommended in situations where individuals have low levels of vitamin B3 or require additional support for skin-related conditions.

Written By Douglas C. Goldberg, MD

Reviewed By Philip Schein, MD

Last Updated 28 Nov 2025

Nicotinamide Uses

Nicotinamide is used for various health conditions, primarily related to vitamin B3 deficiency and skin health.

Treating and preventing vitamin B3 deficiency.
Managing certain skin conditions like acne.
Supporting overall skin health and reducing inflammation.
Potentially aiding in the management of certain inflammatory conditions.

How Nicotinamide Works

Nicotinamide works by replenishing vitamin B3 levels in the body, which is essential for converting nutrients into energy and repairing cellular damage.

It helps improve skin health by reducing inflammation and supporting the skin barrier function.

As a form of vitamin B3, it is involved in the metabolism of fats and sugars, which is vital for maintaining healthy cells.

Common side effects of Nicotinamide

Not everyone experiences side effects from nicotinamide, and many effects are mild and temporary if they occur.

Nausea
Headache
Dizziness
Stomach upset
Flushing of the skin
Itching

If you experience serious or persistent symptoms, contact a healthcare professional.

Monitor for any unusual symptoms and report them to your doctor.
Avoid excessive alcohol consumption while using nicotinamide.
Inform your healthcare provider of any other supplements or medications you are taking to avoid interactions.
Do not use if you have a known allergy to nicotinamide or any of its components.
Consult a doctor if you are pregnant or breastfeeding before using nicotinamide.

Always consult with your healthcare provider for personalized medical advice.

Frequently Asked Questions

What is nicotinamide used for?

Nicotinamide is used to treat vitamin B3 deficiency and support skin health, among other uses.

How does nicotinamide work?

It replenishes vitamin B3 levels, aiding in energy metabolism and reducing skin inflammation.

Are there any common side effects of nicotinamide?

Common side effects may include nausea, headache, dizziness, and stomach upset.

Can I take nicotinamide with other medications?

It’s important to talk to your doctor about any other medications or supplements you are taking to avoid potential interactions.

Is it safe to use nicotinamide during pregnancy?

Consult your healthcare provider before using nicotinamide during pregnancy or while breastfeeding.