Active Ingredient

Norethindrone

Norethindrone is a type of medication known as a progestin. It is commonly used in various hormonal treatments.

This medication can be used in different situations, such as managing menstrual disorders or as part of hormone replacement therapy.

Written By Douglas C. Goldberg, MD

Reviewed By Philip Schein, MD

Last Updated 28 Nov 2025

Available Norethindrone Brands

Aygestin

Strengths 5mg

Norethindrone is typically used for several hormonal and reproductive health issues.

Norethindrone works by mimicking the actions of natural progesterone, a hormone involved in the menstrual cycle and pregnancy.

It helps regulate the menstrual cycle and can prevent ovulation, which is useful in contraceptive applications.

By altering the lining of the uterus, it can also help manage menstrual disorders and reduce symptoms of endometriosis.

Not everyone experiences side effects with norethindrone, and many are mild and temporary.

If you experience serious or persistent symptoms, contact your doctor.

What is norethindrone used for?

Norethindrone is used for managing menstrual disorders, as a contraceptive, and for treating endometriosis symptoms.

How does norethindrone prevent pregnancy?

Norethindrone prevents pregnancy by inhibiting ovulation and altering the uterine lining, making it less suitable for implantation.

Can I take norethindrone if I have a history of blood clots?

You should discuss your medical history, including any history of blood clots, with your doctor before taking norethindrone.

What should I do if I miss a dose of norethindrone?

If you miss a dose, contact your healthcare provider for advice on how to proceed.

Are there any dietary restrictions while taking norethindrone?

There are no specific dietary restrictions, but it’s best to discuss your diet and any supplements with your doctor.