Active Ingredient

Pioglitazone

Pioglitazone is a medication used to help control blood sugar levels in adults. It is often prescribed for people with type 2 diabetes.

This medication works best when used alongside a healthy diet and regular exercise.

Written By Douglas C. Goldberg, MD

Reviewed By Philip Schein, MD

Last Updated 28 Nov 2025

Available Pioglitazone Brands

Actos

Strengths 15mg, 30mg, 45 mg

Pioglitazone is primarily used to manage blood sugar levels in certain conditions.

Pioglitazone works by increasing the body’s sensitivity to insulin, a natural hormone that helps control blood sugar levels.

It belongs to the thiazolidinedione class, which helps the cells in your body use glucose more effectively.

This action helps lower blood sugar levels and improve overall glucose control.

Not everyone experiences side effects with Pioglitazone, and many side effects are mild and temporary.

If you experience serious or persistent side effects, contact your doctor.

Regularly monitor your blood sugar levels as advised by your healthcare provider.
Avoid excessive alcohol consumption while taking this medication.
Inform your doctor about any other medications or supplements you are taking to avoid interactions.
Do not use Pioglitazone if you have severe heart failure or active bladder cancer.
Report any unusual symptoms, such as difficulty breathing or sudden weight gain, to your doctor immediately.

Always consult your doctor before making any changes to your medication or lifestyle.

What is Pioglitazone used for?

Pioglitazone is used to help control blood sugar levels in adults with type 2 diabetes.

How does Pioglitazone work?

It works by increasing the body’s sensitivity to insulin, helping to control blood sugar levels more effectively.

Can Pioglitazone cause weight gain?

Yes, weight gain is a possible side effect of Pioglitazone. Discuss any concerns with your doctor.

Is it safe to drink alcohol while taking Pioglitazone?

It’s advisable to limit alcohol consumption while taking Pioglitazone. Alcohol can affect blood sugar levels.

What should I do if I miss a dose of Pioglitazone?

If you miss a dose, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double up.