Active Ingredient

Piroxicam

Piroxicam is a medication belonging to the class of nonsteroidal anti-inflammatory drugs (NSAIDs). It is commonly used to relieve pain and inflammation associated with various conditions.

This medication is often prescribed for managing symptoms of arthritis and other musculoskeletal disorders. It helps improve function and quality of life for those experiencing chronic pain.

Written By Douglas C. Goldberg, MD

Reviewed By Philip Schein, MD

Last Updated 28 Nov 2025

Available Piroxicam Brands

Feldene

Strengths 10 mg, 20mg

Piroxicam Uses

Piroxicam is used to alleviate pain and reduce inflammation in several conditions. It is typically prescribed for:

Osteoarthritis
Rheumatoid arthritis
Ankylosing spondylitis
Musculoskeletal pain
Post-operative pain

How Piroxicam Works

Piroxicam works by inhibiting the production of certain chemicals in the body that cause inflammation and pain. These chemicals are known as prostaglandins.

By reducing the levels of prostaglandins, Piroxicam helps decrease swelling, pain, and stiffness in the joints and muscles.

This mechanism makes it effective in treating conditions that involve chronic inflammation and pain.

Common side effects of Piroxicam

Not everyone will experience side effects from Piroxicam, and many side effects are mild and temporary. However, some common side effects include:

Stomach upset
Nausea
Dizziness
Headache
Heartburn
Diarrhea
Rash
Edema (swelling)

If you experience serious or persistent symptoms, contact your doctor promptly.

Take Piroxicam with food or a glass of milk to minimize stomach upset.
Avoid consuming alcohol while taking this medication, as it may increase the risk of stomach bleeding.
Inform your doctor of all medications you are taking to avoid interactions.
Do not use Piroxicam if you have a history of allergic reactions to NSAIDs.
Monitor for any unusual symptoms and contact your healthcare provider if they occur.

Always consult your doctor or healthcare provider for advice tailored to your health condition.

Frequently Asked Questions

What is Piroxicam used for?

Piroxicam is used to relieve pain and inflammation in conditions like arthritis, musculoskeletal pain, and post-operative pain.

How long does it take for Piroxicam to work?

The effects of Piroxicam can usually be felt within a few hours, but it may take longer for full benefits to be noticed.

Can I take Piroxicam with other medications?

You should inform your doctor about all the medications you are taking, as Piroxicam can interact with other drugs.

Is Piroxicam safe for long-term use?

Long-term use of Piroxicam should be monitored by a healthcare provider due to potential risks, such as gastrointestinal issues.

Can I drink alcohol while taking Piroxicam?

It is advisable to avoid alcohol while taking Piroxicam, as it can increase the risk of stomach bleeding.