Active Ingredient

Prilocaine

Prilocaine is a type of local anesthetic used to numb specific areas of the body. It is commonly used in medical procedures to prevent pain during minor surgeries or other interventions.

It works by blocking nerve signals in the body, providing temporary relief from pain or discomfort.

Written By Douglas C. Goldberg, MD

Reviewed By Philip Schein, MD

Last Updated 28 Nov 2025

Prilocaine Uses

Prilocaine is typically used in medical settings for various procedures and conditions.

Numbing the skin before minor surgical procedures
Relieving pain from dental procedures
Providing local anesthesia for diagnostic tests
Used in combination with other anesthetics for more extensive anesthesia

How Prilocaine Works

Prilocaine works by blocking sodium channels in nerve cells. This action prevents the initiation and transmission of nerve signals.

By blocking these signals, prilocaine temporarily numbs the targeted area, reducing pain and discomfort.

It belongs to the local anesthetic class of medications, similar to lidocaine and other anesthetics.

Common side effects of Prilocaine

Not everyone experiences side effects with prilocaine, and many of them are mild and temporary.

Redness at the application site
Mild swelling
Itching
Numbness extending beyond the treated area
Dizziness
Headache

If you experience serious or persistent side effects, contact your healthcare provider.

Frequently Asked Questions

How quickly does prilocaine work?

Prilocaine typically begins to work within a few minutes after application, providing numbness to the area.

How long does the effect of prilocaine last?

The numbing effect of prilocaine usually lasts for a couple of hours, but this can vary depending on the area treated and the dose used.

Is prilocaine safe for everyone?

Prilocaine is generally safe when used as directed, but it may not be suitable for people with certain medical conditions. Always consult your doctor before use.

Can prilocaine be used with other medications?

Prilocaine can interact with other medications, so it’s important to inform your healthcare provider about all drugs you are taking.

What should I do if I experience side effects?

If you experience side effects, especially if they are severe or persistent, contact your healthcare provider for guidance.