Active Ingredient

Primaquine

Primaquine is an antimalarial medication used to treat and prevent malaria. It is specifically effective against certain stages of the malaria parasite.

This medication is often used in combination with other antimalarial drugs to enhance its effectiveness.

Written By Douglas C. Goldberg, MD

Reviewed By Philip Schein, MD

Last Updated 28 Nov 2025

Available Primaquine Brands

Primaquine

Strengths 7.5 mg, 15 mg

Primaquine Uses

Primaquine is primarily used in the treatment and prevention of malaria. It can be particularly useful in specific scenarios:

Treatment of malaria caused by Plasmodium vivax or Plasmodium ovale.
Prevention of malaria relapse in areas where these types are common.
Part of combination therapy for certain malaria infections.

How Primaquine Works

Primaquine works by interfering with the growth and multiplication of the malaria parasites in the blood and tissues. It is particularly effective against the liver stages of the parasite, which helps prevent relapse.

This action helps to clear the parasites from the body and reduce the risk of transmission.

Common side effects of Primaquine

Not everyone experiences side effects with Primaquine, and many side effects are mild and temporary. However, some common side effects include:

Nausea
Vomiting
Stomach upset
Headache
Dizziness
Fatigue

If you experience persistent or severe side effects, contact your healthcare provider.

Frequently Asked Questions

What is Primaquine used for?

Primaquine is used to treat and prevent malaria, especially types caused by Plasmodium vivax and Plasmodium ovale.

How does Primaquine work?

It works by interfering with the growth of malaria parasites in the blood and tissues, particularly effective against liver stages.

Can Primaquine cause side effects?

Yes, some common side effects include nausea, vomiting, and dizziness. Most are mild and temporary.

Is it safe to drink alcohol with Primaquine?

It is advisable to avoid alcohol while taking Primaquine as it may increase the risk of side effects.

Can I take Primaquine if I have a blood disorder?

You should inform your doctor about any blood disorders before starting Primaquine, as it may not be suitable.