Rosiglitazone

Rosiglitazone is a medication used to help manage blood sugar levels in adults with type 2 diabetes. It is typically used when diet and exercise alone are not enough to control blood sugar.

It belongs to a class of drugs called thiazolidinediones, which work by improving the body’s response to insulin.

Information about Rosiglitazone

Rosiglitazone Uses

Rosiglitazone is primarily used to improve blood sugar control in adults with type 2 diabetes. It is often part of a comprehensive treatment plan including diet and exercise.

Management of type 2 diabetes
Improvement of insulin sensitivity
Reduction of blood sugar levels

How Rosiglitazone Works

Rosiglitazone works by increasing the sensitivity of muscle, fat, and liver cells to insulin, allowing these cells to remove glucose from the blood more effectively.

This helps lower blood sugar levels and improve the body’s use of insulin.

As a thiazolidinedione, Rosiglitazone targets specific receptors in the body to bring about these changes.

Common side effects of Rosiglitazone

Not everyone will experience side effects from Rosiglitazone, and many side effects are mild and temporary. However, some people may experience the following:

Headache
Back pain
Respiratory infection
Swelling due to fluid retention
Weight gain
Fatigue

If you experience any serious or persistent symptoms, contact your doctor.

CONTENT DETAILS

Written By

Douglas C. Goldberg, MD

Reviewed By

Philip Schein, MD

Last updated

28 Nov 2025 | 03:00 PM (UTC)

Medicine brands for Rosiglitazone

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Dosage: 2-mg, 4-mg
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Expert advice for Rosiglitazone

Monitor your blood sugar levels regularly as advised by your healthcare provider.
Avoid consuming large amounts of alcohol while taking this medication.
Inform your doctor of any other medications you are taking to avoid interactions.
Report any signs of heart problems, such as shortness of breath or swelling, to your doctor immediately.
Do not take Rosiglitazone if you have severe heart failure.

Always consult your doctor for personalized medical advice and before making any changes to your medication regimen.

Frequently Asked Questions

What does Rosiglitazone do?

Rosiglitazone helps control blood sugar levels in adults with type 2 diabetes by improving the body’s response to insulin.

How long does it take for Rosiglitazone to work?

The effect of Rosiglitazone on blood sugar levels can be observed within a few weeks, but it may take longer for full benefits.

Can Rosiglitazone be taken with other diabetes medications?

Rosiglitazone may be used in combination with other diabetes medications, but always under the guidance of a healthcare provider.

What should I avoid while taking Rosiglitazone?

Avoid excessive alcohol consumption and inform your doctor about all other medications you are taking to prevent interactions.

Is Rosiglitazone safe for everyone with diabetes?

Rosiglitazone is not suitable for everyone, especially those with severe heart failure. Consult your doctor to determine if it is right for you.