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Selegiline
Selegiline is a medication used to manage certain neurological conditions. It is commonly prescribed to help improve symptoms associated with these disorders.
Selegiline works by influencing chemicals in the brain, which can help improve mood and movement.
Information about Selegiline
Selegiline Uses
Selegiline is typically used for managing symptoms of specific neurological conditions.
- Parkinson’s disease
- Major depressive disorder (in certain cases)
- As an adjunct therapy in certain neurological disorders
How Selegiline Works
Selegiline works by inhibiting an enzyme called monoamine oxidase type B (MAO-B). This enzyme breaks down dopamine in the brain.
By reducing the activity of MAO-B, Selegiline helps increase the levels of dopamine, which can improve movement and mood symptoms.
This mechanism is particularly beneficial in conditions like Parkinson’s disease, where dopamine levels are typically low.
Common side effects of Selegiline
Not everyone experiences side effects with Selegiline, and many are mild and temporary. However, it’s important to be aware of potential reactions.
- Dizziness
- Nausea
- Dry mouth
- Insomnia
- Stomach upset
- Headache
If you experience serious or persistent symptoms, contact your healthcare provider.
CONTENT DETAILS
Written By
Douglas C. Goldberg, MD
Reviewed By
Philip Schein, MD
Last updated
28 Nov 2025 | 03:00 PM (UTC)
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Expert advice for Selegiline
- Monitor your symptoms and report any significant changes to your doctor.
- Avoid consuming large amounts of alcohol while taking Selegiline.
- Inform your healthcare provider about all other medications you are taking to avoid interactions.
- Do not suddenly stop taking Selegiline without consulting your doctor.
- Be cautious when standing up quickly, as Selegiline can cause dizziness.
Always consult your doctor for personalized medical advice.
Frequently Asked Questions
What is Selegiline used for?
Selegiline is primarily used for managing symptoms of Parkinson’s disease and may be used in certain cases of depression.
How does Selegiline work?
Selegiline works by inhibiting the enzyme MAO-B, which helps increase dopamine levels in the brain, improving mood and movement.
Can Selegiline cause side effects?
Yes, like any medication, Selegiline can cause side effects such as dizziness, nausea, and insomnia. Most side effects are mild and temporary.
Are there any interactions with Selegiline?
Selegiline can interact with other medications, so it’s important to inform your doctor about all drugs you are taking.
Is it safe to drink alcohol while taking Selegiline?
It’s advisable to avoid consuming large amounts of alcohol while taking Selegiline, as it can increase the risk of side effects.