Active Ingredient

Tenofovir Alafenamide

Tenofovir Alafenamide is an antiretroviral medication used to manage certain viral infections. It is often prescribed as part of a combination therapy.

This medication is primarily used to treat chronic infections and help maintain a healthier immune system.

Written By Douglas C. Goldberg, MD

Reviewed By Philip Schein, MD

Last Updated 28 Nov 2025

Tenofovir Alafenamide Uses

Tenofovir Alafenamide is commonly used to manage viral infections. It is part of a comprehensive treatment plan.

Treatment of chronic hepatitis B virus infection in adults.
Part of combination therapy for HIV-1 infection in adults.

How Tenofovir Alafenamide Works

Tenofovir Alafenamide works by inhibiting the replication of viruses in the body. It belongs to the class of drugs known as antiretrovirals.

This medication interferes with the viral enzyme reverse transcriptase, which is crucial for the virus to multiply.

By doing so, it helps to lower the amount of virus in the body, aiding the immune system to function better.

Common side effects of Tenofovir Alafenamide

Not everyone experiences side effects with Tenofovir Alafenamide, and many are mild and temporary. However, some common side effects can occur.

Headache
Nausea
Dizziness
Fatigue
Stomach pain
Diarrhea

If you experience serious or persistent side effects, contact your healthcare provider.

Regularly monitor your health and report any unusual symptoms to your doctor.
Avoid consuming large amounts of alcohol while taking this medication.
Inform your doctor about any other medications or supplements you are taking to avoid interactions.
Do not stop taking the medication without consulting your doctor, even if you feel well.
If you experience symptoms like severe abdominal pain, contact your doctor immediately.

Always consult your healthcare provider for personalized medical advice.

Frequently Asked Questions

What is Tenofovir Alafenamide used for?

It is used to treat chronic hepatitis B and as part of combination therapy for HIV-1 infection.

How does Tenofovir Alafenamide work?

It works by inhibiting the replication of viruses, helping to reduce the viral load in the body.

Can I drink alcohol while taking Tenofovir Alafenamide?

It’s best to avoid large amounts of alcohol as it can increase the risk of side effects.

What should I do if I miss a dose?

If you miss a dose, take it as soon as you remember. If it’s almost time for the next dose, skip the missed dose.

Are there any dietary restrictions while taking this medication?

There are no specific dietary restrictions, but it’s important to maintain a balanced diet and follow your doctor’s advice.