Active Ingredient

Trihexyphenidyl

Trihexyphenidyl is a medication used to help manage certain movement disorders. It is particularly helpful for conditions that affect muscle control.

This medication is often prescribed to adults experiencing symptoms related to Parkinson’s disease or other similar disorders.

Written By Douglas C. Goldberg, MD

Reviewed By Philip Schein, MD

Last Updated 28 Nov 2025

Available Trihexyphenidyl Brands

Artane

Strengths 2mg

Trihexyphenidyl Uses

Trihexyphenidyl is commonly used to treat symptoms associated with movement disorders. It helps improve muscle control and reduce stiffness.

Parkinson’s disease
Drug-induced extrapyramidal symptoms
Muscle stiffness
Involuntary muscle movements

How Trihexyphenidyl Works

Trihexyphenidyl works by blocking certain neurotransmitters in the brain, specifically acetylcholine. This helps to balance the levels of chemicals in the brain that control muscle movement.

As an anticholinergic agent, it reduces the activity of acetylcholine, leading to improved muscle control and reduced muscle stiffness.

Common side effects of Trihexyphenidyl

Not everyone experiences side effects with Trihexyphenidyl, and many are mild and temporary. However, it’s important to be aware of them.

Dry mouth
Blurred vision
Dizziness
Nausea
Constipation
Nervousness
Difficulty urinating

If you experience serious or persistent side effects, contact your doctor.

Frequently Asked Questions

What is Trihexyphenidyl used for?

Trihexyphenidyl is used to manage symptoms of Parkinson’s disease and other movement disorders.

How does Trihexyphenidyl work?

It works by blocking acetylcholine, which helps to reduce muscle stiffness and improve movement control.

Can I drink alcohol while taking Trihexyphenidyl?

It’s best to limit alcohol as it can increase dizziness and drowsiness while on this medication.

What should I do if I miss a dose?

If you miss a dose, take it as soon as you remember, unless it’s almost time for your next dose. Do not double up.

Are there any dietary restrictions while taking Trihexyphenidyl?

No specific dietary restrictions, but staying hydrated can help manage dry mouth, a common side effect.