Active Ingredient

Ursodeoxycholic Acid

Ursodeoxycholic Acid is a bile acid that is used to help improve liver function. It is commonly prescribed for conditions where the flow of bile is reduced or blocked.

This medication can help dissolve certain types of gallstones and improve symptoms in some liver diseases.

Written By Douglas C. Goldberg, MD

Reviewed By Philip Schein, MD

Last Updated 28 Nov 2025

Available Ursodeoxycholic Acid Brands

Urso

Strengths 150 mg, 300 mg

Ursodeoxycholic Acid Uses

Ursodeoxycholic Acid is typically used in the management of liver and gallbladder conditions. It helps in the following conditions:

Dissolving cholesterol gallstones in patients who cannot undergo surgery.
Managing primary biliary cholangitis, a type of liver disease.
Treating certain liver disorders related to cystic fibrosis.
Improving liver function in patients with chronic liver disease.

How Ursodeoxycholic Acid Works

Ursodeoxycholic Acid works by reducing the production of cholesterol in the liver and by slowly dissolving cholesterol gallstones.

It also helps improve the flow of bile in patients with liver diseases, which can alleviate symptoms and improve liver function.

By modifying the composition of bile, it helps prevent damage to liver cells.

Common side effects of Ursodeoxycholic Acid

Not everyone experiences side effects with Ursodeoxycholic Acid, and many are mild and temporary. Common side effects include:

Nausea
Diarrhea
Stomach discomfort
Headache
Dizziness
Back pain
Hair thinning

If you experience serious or persistent side effects, consult your doctor promptly.

Take this medication with food to reduce stomach upset.
Avoid heavy alcohol consumption while on this medication.
Inform your doctor about any other medications you are taking to avoid potential interactions.
Do not use this medication if you have a blockage in your bile ducts.
Regular monitoring of liver function may be recommended by your doctor.

Always consult your doctor for personalized medical advice and before making any changes to your medication regimen.

Frequently Asked Questions

What is Ursodeoxycholic Acid used for?

It is used to dissolve certain types of gallstones and to treat liver conditions such as primary biliary cholangitis.

How long does it take for Ursodeoxycholic Acid to work?

The time it takes to notice improvements can vary. It may take several months to dissolve gallstones or improve liver function.

Is Ursodeoxycholic Acid safe for long-term use?

It can be used long-term under medical supervision, especially for chronic liver conditions. Regular monitoring by a doctor is recommended.

Can I take Ursodeoxycholic Acid with other medications?

Inform your doctor about all medications you are taking, as Ursodeoxycholic Acid may interact with certain drugs.

Are there any dietary restrictions while taking Ursodeoxycholic Acid?

It’s best to take this medication with food. Discuss any specific dietary concerns with your healthcare provider.