Active Ingredient

Zidovudine

Zidovudine is a medication used to manage certain viral infections. It is commonly prescribed for individuals living with HIV.

This medication helps in controlling the virus and improving the quality of life for those affected.

Written By Douglas C. Goldberg, MD

Reviewed By Philip Schein, MD

Last Updated 28 Nov 2025

Available Zidovudine Brands

Retrovir

Strengths 100mg, 300mg

Zidovudine is primarily used to help manage viral infections and improve the immune system.

Zidovudine works by inhibiting the action of reverse transcriptase, an enzyme crucial for the replication of HIV.

By blocking this enzyme, Zidovudine helps to prevent the virus from multiplying in the body.

This action helps to reduce the viral load and maintain a healthier immune system.

Not everyone will experience side effects from Zidovudine, and many side effects are mild and temporary.

If you experience serious or persistent side effects, contact your doctor.

Regularly monitor your blood counts as advised by your doctor.
Avoid alcohol while taking this medication to minimize liver strain.
Inform your healthcare provider about any other medications you are taking to avoid interactions.
Do not stop taking Zidovudine without consulting your doctor, even if you feel better.
Report any unusual symptoms or side effects to your healthcare provider promptly.

Always consult your doctor for personalized medical advice.

What is Zidovudine used for?

Zidovudine is used to manage HIV infection and prevent mother-to-child transmission during childbirth.

How does Zidovudine work?

It inhibits an enzyme called reverse transcriptase, which is needed for the HIV virus to multiply.

Can I drink alcohol while taking Zidovudine?

It is advisable to avoid alcohol to prevent additional strain on your liver.

What should I do if I miss a dose?

If you miss a dose, take it as soon as you remember unless it is almost time for your next dose.

Are there any serious side effects of Zidovudine?

Serious side effects are rare, but if you experience symptoms like severe fatigue or unusual bleeding, contact your doctor.