Cialis is prescribed for treating erectile dysfunction (ED). It’s commonly called a “weekend pill” due to an unbelievably prolonged duration of its activity, which lasts on average 36 hours. Such long-lasting action (if you take it before sexual act) is one of the longest compared to other medicines against problems with erection.
The Impact of the Medication
Tadalafil is manufactured under brand name Cialis. Tadalafil provides blocking of enzyme’s action, which is also called as cGMP-specific phosphodiesterase type-5 (PDE-5). cGMP is a component, which stimulates the relaxation of smooth muscles. The enzyme breaks cGMP down. If PDE-5 is blocked the cGMP’s levels are increased. Consequently, smooth muscles relax and blood vessels get wider (this process is known as a vasodilation).
Enhanced amount of PDE-5 is common for such organs as lungs, retina and penis. It is presented in a minor quantity in blood vessels’ smooth muscle cells and muscles.
The Maximal Efficiency of Cialis
When Taken as Needed
The highest rate of Cialis concentration in plasma is observed from half an hour to 6 hours after (average time is 2 h) taking the necessary dosage. The required effect of the drug last approximately 36 hours, which is especially appreciated by the patients.
The medicine is allowed to be consumed for a long period. According to the study of the Italian scientists Montorsi F, Verheyden B, Meuleman E and others (held in 2004) Tadalafil in doses from 5 to 20 mg per day for 18 or 24 months is completely safe and greatly tolerated.
Alcohol beverages (especially in huge quantities) are not recommended to be combined with Cialis, since they minimize blood pressure and lower sexual performance.
Specialists don’t recommend to eat grapefruit during therapy with Cialis.
Consult licensed healthcare specialist before trying any drug for ED to avoid severe side effects, which may occur in men with some medical conditions.
Immediately visit your doctor in case of feeling dizziness, painful sensations, nauseous during sex, tingling in arms, jaw, neck or chest, numbness.
It’s prohibited to mix Cialis with drugs, based on nitrate (for instance, nitroglycerin, isosorbide dinitrate/mononitrate) in case of chest pain and heart conditions. Taking Cialis together with recreational medicines (for example, “poppers”) can lead to the sudden and dramatic drop in blood pressure.
When Does the Peak Action of The Drug Take
Place With Daily Usage?
There is a version of medicine which has to be taken in small dosages. That is why everyday usage is allowed. This property of Cialis allows you to have sex whenever you desire. Most anti-ED medications are taken at certain time, not daily, which isn’t convenient for patients, who want to enjoy sex constantly.
Cialis (daily) may show its effect not immediately after taking. The organism may require several days to get used to the medication.
You should start the therapy with 2.5 mg. If no evident changes happen, the dose should be increased to 5 mg. Keep in mind that men who take Cialis everyday are at risk of facing rapid lowering of blood pressure in case they drink a lot of alcohol.
Viagra and Cialis are usually administered on
demand, that is, a person takes a pill when he plans to have sex in near time.
Sometimes, people need to take these tabs every day. Is it ok? Are there any
health risks?
Everyday
Use of Viagra
Theoretically, one can use Viagra on an everyday basis. However, in practice such cases are not very frequent as not everyone (especially after 40, when prevalence of ED begins to rise) has sex every day. Moreover, some reported occasions of blindness which may be associated with prolonged administration of sildenafil may play a role of a preventive factor despite the fact that direct link between its use and hearing impairment hasn’t been established. Moreover, sildenafil is an active component of Revatio drug. Doctors prescribe it for treating pulmonary arterial hypertension, and patients need to take it every day. So we can conclude that “blue diamond” with the same sildenafil in composition is safe when taking on an ongoing basis.
At the same time, the medication doesn’t cause
tolerance worsening. According to the study by James G McMurray et al. (Medical Affiliated Research Center, Pfizer Inc. etc., 2007), most of
participants who had used the medication for a long time responded
affirmatively when the surveyors asked them about successfulness of erectile
dysfunction treatment. This means that durable administration of Viagra doesn’t
cause loss of tolerability, it maintains the same effectiveness.
Conclusion: Viagra can be taken every day, that would be ok for your health. However, if you practice daily using (especially in high dosages), it is recommended to consult a healthcare professional.
Administration
of Cialis on Daily Basis
Well, it depends. There are two recommended modes of taking Cialis. The first one is taking it on demand (as needed). Considering the fact, that tadalafil acts up to 1.5 days (36 hours), its administering on an everyday basis may be associated with increased risk of side effects as the substance just doesn’t have time to leave the body in full. Two pills are stacked, and the concentration of tadalafil in the blood remarkably increases, causing semi-overdose condition.
The second mode is
daily treatment. A
male can take low doses of Cialis (2.5 or 5 mg) every day, preferably at the
same time, say 12 am. Such treatment can last long. It features the great
advantage: there is no need for a patient to plan sex at all, he can have it anytime,
as the active substance remains in the body on a permanent basis. This regime
can bring more romanticism in a couple’s relationship.
Interestingly, Cialis in minimal doses can treat benign prostate hyperplasia (prostate adenoma, BPH in short). Moreover, according to Konstantinos Hatzimouratidis (Hellenic Aristotle University of Thessaloniki, 2014), this is the only pharmaceutical product that can successfully treat both BPH and ED, because traditionally used medications for reducing urinary tract symptoms, including α-adrenergic antagonists and 5α-reductase inhibitors, are associated with sexual adverse events and may worse impotence.
Conclusion: Cialis in low dosages (2.5 mg or 5 mg) can be used daily, this has been officially allowed. If you take higher dosages (10 mg or 20 mg), time interval between doses should desirably be 36 hours.
Takeaways
Both Viagra and Cialis can be taken every day.
But you can do that only if there is a real need. Plus, in case of Cialis you need
to use the lowest dosage.
Viagra is one of the most known pills in the
world. However, its branded version, to put it bluntly, is not cheap.
Fortunately, there is a widely accepted scheme according to which, when a patent
for an original medication expires, other pharmaceutical companies (which are
eligible to do this) acquire the right to manufacture an unpatented drug
(generic). After appearance of generic products, original Viagra sales didn’t nosedive
but remarkably decreased. Such a situation even forced Pfizer to announce the launch
of its own generic product line. However, other drugmakers managed to earn
fame, so now their drugs are very popular.
Well, do you want to know exactly which companies produce generics of Viagra? Then this article is for you.
Indian
Drugmakers that Produce Sildenafil Generics
India is the biggest generic supplier in the
world. Many companies producing generics of different kinds are based in Indian
jurisdiction (examples are Cipla and Dr. Reddy’s). Such a position of India is
associated with favorable conditions for pharmaceutical companies’ operating, relatively
low salaries for workers, and some inapproachability with regard to patents’
action and lawsuits of genuine products’ manufacturers. Indian medicines are
often sold over-the-counter.
Ajanta Pharma is a specialized pharmaceutical company engaged in the development, production and marketing of high-quality medicines in both the Indian and international markets. This company was founded in 1973 with headquarters in Mumbai-India. Thus, this company has extensive experience (over 40 years) in manufacturing medicines. Ajanta consistently provides high quality affordable medicines for patients in different parts of the world. Recently, it has focused its production on exports and on the final Western consumer, in particular, tablets of this manufacturer are widely advertised in Europe (although they are not approved in all countries).
Ajanta Pharma is probably the most known
producer of generic sildenafil, as this company produces Kamagra, Kamagra
Jelly, and Kamagra Super. Let’s take a brief look at these preparations:
Kamagra is
an ordinary sildenafil. Unlike genuine Viagra (the so-called “blue diamond”),
this drug has turquois color. The most popular dosage is 100mg, but 50mg is
also sold.
Kamagra Jelly.
This is a unique remedy which is marketed in a gel form contained in sachets. It
features various flavors such as banana, mint, strawberry, pineapple, orange,
chocolate, cream, mango, rose and a few others.
Kamagra Super.
This is a combination of sildenafil (an anti-ED agent) and dapoxetine, a
substance which helps to handle premature ejaculation.
Sun Pharmaceutical Industries Ltd.
Sun Pharma was incorporated back in 1983. Initially it sold psychiatric products (five medications). In 1994 it launched IPO (Initial Public Offering). After parabolic growth, it expanded the network of drugs’ sale across more than 20 counties. Regarding innovative activity of the company it’s worth mentioning that it introduced gastroenterology products in India (in 1989).
This company produces, in particular, Caverta
medication. It is interesting that earlier Caverta was produced by Sun
Pharmaceutical Industries Ltd, but on 25th March 2015 Sun Pharma
completed the acquisition of Ranbaxy Laboratories, so nowadays Ranbaxy actually
doesn’t exist as a separate firm being an integral part of Sun.
In addition, according to the information on
the company’s official website, it offers sildenafil in different dosages under
the name RAN SILDENAFIL.
Centurion
Laboratories
Centurion Laboratories is one of the largest
generic manufacturing plants located in India. Centurion Laboratory produces
more than 100 types of generics, from simple drugs, sedatives, drugs for the
treatment of erectile dysfunction to serious anti-hepatitis, anti-tuberculosis,
and anti-cancer drugs. Centurion Laboratories Pvt. was founded in 1998 in the
city of Guyarat. In 2017, the company’s turnover amounted to more than $5
billion.
Centurion Labs produces several names of Viagra
generics, in particular, Eregra and
Cenforce. In addition to generic sildenafil, the company also manufactures
generics of other PDE5 inhibitors, as well as drugs for the treatment of
premature ejaculation, and natural remedies for the treatment of impotence.
Ranbaxy
Ranbaxy Laboratories Limited is the largest
pharmaceutical corporation in India, a multinational manufacturer of a wide assortment
of medicines.
Ranbaxy was established in 1961. In 2008, it entered into an alliance with one of the biggest Japanese innovative businesses, Daiichi Sankyo Company Ltd. As a result of this merger, the major player in the market of innovative and generic drugs emerged. The combined company today is among the 20 largest pharma behemoths in the world. In particular, it produces supplements (for example, iron-containing ones), antibacterial drugs, drugs for treating hypertension, medicines for men’s health, and many others.
The most known generic drug manufactured by
Ranbaxy is Caverta.
Cipla
Cipla Limited is an Indian multinational
pharmaceutical and biotechnology company, headquartered in Mumbai, India. Its production
facilities are located in Belgium, Surrey in the EU, Miami, Florida in the
United States, as well as in other countries. The company specializes in the
production of drugs for respiratory, cardiovascular diseases, arthritis,
diabetes, erectile dysfunction, and other conditions. It was founded by the
Indian nationalist and scholar Khwaja Abdul Hamied back in 1935 in Mumbai. The
products of this Indian corporation are approved by the American FDA.
Sipla produces a medication which is called Silagra. Another less-known generic is
Assurans (in a tableted form).
Other Manufacturers
There are also other Indian companies less preeminent than the abovementioned ones. These are FDC (Zerect tabs), Medley (Vigreks tab), Bestochem (Rocky-50), Human Pharmacia (Sex-Gra), Dr. Reddy’s Lab (Rezum), Dynamic (Ratigra), Protec (Progra), Zydus Alidac (Penegra), Kopran (Nyte tab), Unichem (Erix), Torrent (Androz), IND-SWIFT (Adams Delite), and a bunch of others.
Canadian
Companies Manufacturing Generic Viagra
Canada is considered a world leader by a
quantity of online pharmacies which are based in this country. But in fact, in
this country there are no many manufacturers producing Viagra generics
comparing, for instance, with India.
Teva
Teva is one of the world’s leading manufacturers of generic drugs, which is among the 15 largest international pharmaceutical manufacturers. In addition to a wide selection of high-quality generics in such areas as cardiology, pulmonology, oncology, neurology and urology, the company also produces its own innovative medical products.
Teva is a company originating from Israel (its earliest
predecessor was Jerusalem-based “Salomon, Levin, and Elstein Ltd.”).
But it has multiple affiliated firms in different companies of the world, in
particular, in Canada. Sildenafil Teva is a recognizable drug among many
patients.
Pharmaris Canada
Pharmaris
Canada is a young company, whose activity began in Peru in 2009 with subsequent
expanding to other countries (Peru, Chile, Canada, and others). The Canadian
branch is based in British Columbia.
It should also be noted that Mylan, a widely known pharma company,
has launched sales of generic Viagra in 11 countries. But Canadian facilities
of this corporation most probably don’t produce this medication, and it is not
offered by Canada-based drugstores.
Mexican
Drugmaking Companies
According to statistics, the United Mexican States
is one of the largest markets for erectile dysfunction products (both
pharmaceuticals and herbal products).
In addition, Mexico is famous for its producers of anabolic steroids, which are (although in Mexican pharmacies some anabolics may be bought without a prescription). Keep in mind that some of medications sold in this country may be counterfeited, this applies not only to anabolically active drugs but also to other kinds of meds, including Viagra.
Besides semi-legal and underground
manufacturers, Mexico is a base for many giant pharmaceutical corporations
which have opened affiliate companies there. For instance, these are local
branches of Schering Plough, Boehringer Ingelheim, Bayer, AztraZeneca, and GlaxoSmithKline.
In Mexico, there is also a branch of Pfizer company. It is interesting, that in 2011 Pfizer launched a special version of Viagra in Mexico. This was Viagra Jet (“Tabletas Masticables”), a chewable medication for males who didn’t like swallowing pills or capsules (but it is not known whether this version is sold nowadays). However, males may simply choose Kamagra Jelly.
Which
Dosages Are Offered by Generic Viagra Manufacturers?
Of course, generic drugmakers offer classic
dosages of Viagra, that is 25mg, 50mg, and 100mg. However, other variations are
also possible. Sometimes you can find enhanced doses, like 150mg and 200mg. Some
males can take advantages from increased quantity of sildenafil in the chosen
product, but keep in mind that an increase in dosage does not necessarily mean
improvement of the medication’s effectiveness.
Conclusions
There are a lot of generic Viagra producers on the market. But the key thing for a customer is not the choice of a manufacturer (as manufacturers don’t sell medications directly to users), his task should rather be finding a reliable supplier. Read more: Why is Canadian Health&Care Mall the Best Way to Order Generic Drugs?
Levitra is a drug for treating impotence in men. This is one of the most proven and effective sexual enhancers that can overcome the problem of impotence from the very first dose. The original version of the drug was developed by German specialists, but nowadays generic versions of Levitra (Canadian, Indian) are produced by many pharmaceutical companies.
Often it is not enough to just take a drug, if you want it to act properly, you should follow some rules. Males who suffer from ED may wonder: how to take Levitra to achieve maximum possible effectiveness?
Why Might You Prefer
Levitra?
The most popular ED medication in the world is Viagra. It is known as a preeminent brand, so its sales are still high despite the existence of many competitors on the market. Cialis is probably the most known competitor of the “blue pill” which acts remarkably longer than Viagra. Its duration of effect is 36 hours, while Viagra feature only 4-6 hours. Well, Levitra acts for 4-5 hours. But nevertheless it has decent popularity (especially in some European countries). We believe that there are two reasons for this.
The first one: Levitra is more efficient in patients suffering from diabetes mellitus which often coexists with impotence because it is one of causative factors of sexual weakness (due to diabetes-caused deterioration of the blood circulation).
The second reason: Levitra might be effective in males who haven’t experience proper effect. According to some reviews, patients have tried different ED meds and herbal supplies but only Levitra brought the expected effect.
How to Take Levitra Tablet: Must-Know Tips
It is recommended to take Levitra swallowing the pill down with water. Using other fluids isn’t advised because it is not clearly known how they may interact with the pill’s covering and internal ingredients. There are no reports about dangerous interactions, for example, with milk, but better follow instructions. (Recently we analyzed how to take Viagra: with water or milk.)Moreover, scientists have proven than grapefruit juice may lead to unsafe interactions, as this fruit contains a substance which inhibits an enzyme ensuring proper removal of toxins and pharmaceutical substances from the body. As a result, a concentration of vardenafil in the blood may become iffy.
The medicationcan be taken with food (while you eat), but don’t combine it with high-fat or heavy meal, as this may slow down absorption of the drug, and the onset of effect will be observed later than expected (the medicament usually starts to act 25-60 minutes after ingestion). Levitra works best when taken on an empty stomach, which has been confirmed by patients’ reviews.
Wait aboutan hour before having sex. If you take Levitra, it may be better to plan your sex in advance, as the peak concentration of vardenafil (the key active substance), and, subsequently, the maximum effectiveness is shown 1-2 hours after using. Then the efficiency of the medical remedy begins to decrease, slowly but surely.
Safety Precautions
If you take any medications, herbal/dietary supplements, let your doctor know about that. The medication may dangerously interact with some other drugs (for instance, nitrates, erythromycin, ketoconazole) and supplies (like L-Arginine). Better safe than sorry. Healthcare professionals also recommend to avoid St John’s Wort, a natural remedy for depressions, if a patient takes Levitra or other PDE5 inhibitors.
Discuss your medical history (anamnesis) with a healthcare professional. While general conditions like cold, flu, mild gastritis etc. usually don’t matter, cardiovascular diseases may be factors that prevent Levitra administering. For instance, it is contraindicated to take the tablet if you’ve recently had stroke or another cardiovascular event. The same goes for situations when a patient and/or someone from his family has a history of degenerative ophthalmic diseases.
The maximally allowed dosage of Levitra is 1 pill per day. Don’t take more than 2 pills within a 24-hour period, this may be associated with elevated odds of side effects occurrence.
Don’t combine the medicament with other drugs from the family of PDE5 inhibitors (Cialis, Levitra, Stendra, etc.). Chances to receive a boosted (synergetic) effect are improbable, but the risk of side effects definitely increases.
It is desirable to avoid alcohol or at least minimize its consumption when you are treated with the pill. Alcoholic drinks in huge quantities tend to decrease Levitra effectiveness, moreover, the cumulative action of ethyl alcohol and vardenafil may lead to arterial pressure drop resulting in headaches, weakness and even reluctance to have sex. Several glasses of whiskey in combination with Levitra can cause the opposite effect, not the one that you’ve expected.
Last but
not least, you may use Levitra over a long period of time. This pharmaceutical
product is not addictive, so prolonged usage pose no danger to your health (in
terms of addictiveness). Some males may build up a tolerance to the medication,
but such incidents are really rare.
Cialis is a potent anti-ED drugs and probably is the most serious competitor of Viagra (“blue pill”). It has been existing on the pharmaceutical market for 15 years. Its name is now associated with some myths and misbeliefs. Can it make the penis bigger? This question sometimes arise in patients’ minds. Let’s try to give a science-backed answer to it.
Active
Agent of Cialis
There is a family of medications which are extensively used throughout the world to combat erectile dysfunction in males. These are PDE5 inhibitors (phosphodiesterase type 5 inhibitors). They have similar effects but also feature distinctive characteristics.
For instance, sildenafil is an active substance in Viagra which acts up to 6 hours, while Cialis contain tadalafil, the “champion” by the duration of action (up to 36 hours or 1,5). Cialis is available in several classic dosages: 2.5mg, 5mg, 10mg, and 20mg. If you are taking Cialis for the first time, you can start carefully with 5mg or 10mg pills, but the most commonly used dosage is 20 milligrams.
Well, yes and no. If a man is sexually excited and his body is under influence of Cialis, his organ will become bigger due to naturally occurring erection processes, which are just facilitated by tadalafil. In this sense, it can make erected penis bigger. But when it comes to physical growth of the penis (on a permanent basis), Cialis is helpless. It doesn’t contain hormonal substances and doesn’t activate growth processes in the penile organ. For this purposes, other means are used.
So
What Exactly Does Cialis Do?
The active ingredient of Cialis exerts suppressive effect on PDE5, a natural enzyme which is present in the penis, lungs, and some other parts of the body. However, the medication has a high specifity and acts primarily on the genital area (but a special tadalafil-based drug, Adcirca, is used to treat pulmonary arterial hypertension).
PDE5 suppression leads to a positive effect on a male erection. This is associated with the fact that phosphodiesterase type 5 inhibits cyclic guanosine monophosphate (cGMP) substance. cGMP is responsible for normal erection. Amidst the influence of Cialis, levels of cGMP in penile tissues are increased, which leads to relaxation of smooth musculature, which opens access for the blood flow to enter the organ. When penis is properly filled with blood, it acquires necessary hardness.
Moreover, tadalafil also leads to muscle relaxation in the prostate, urinary bladder and vessel which transports blood to these organs. That’s why it has been officially approved to treat benign prostate enlargement, more precisely, urinary symptoms caused by it. It is now a popular alternative to other established meds for these symptoms, such as α-adrenergic antagonists.
However, as K. Hatzimouratidis at the Aristotle University of Thessaloniki (Greece) rightly points out, it is not just a substitute, since side effects associated with the traditional medical remedies are avoided in case of tadalafil, plus, Cialis is the only medicament which is able to treat both erectile dysfunction and urinary unhealthiness simultaneously.
Like Viagra, Cialis don’t improve libido.
Sexual excitement is a necessary requirement for Cialis’ onset of effect. If
you wanna enhance your libidinal characteristics, try herbal remedies and
adjust your diet (include watermelon, asparagus, walnuts, almonds, black
chocolate, peaches, and shellfish).
The
Bottom Line
Cialis has been shown to significantly improve the ability to achieve sexual intercourse. The medicine helps to trigger and maintain an erection by expanding the blood vessels leading to the penis and improving the blood flow. If there are no other physiological or mental problems in the background, it will definitely work. In case of psychogenic disorders, effectiveness may be lower but it usually still helps. However, it doesn’t help get bigger permanently.
Cialis is a delightful drug that triumphantly
broke into the market in the early 2000s, becoming an influential competitor to
Viagra. However, there are no magic drugs, sometimes even the brightest stars
of the pharmaceutical industry do not work for some patients (or lose their
effectiveness).
Cialis is a drug that can be used on demand or
on a daily basis (and in the case of daily intake, it often works better). For
some men, it works well, but then reduces effectiveness. What can this be
forced by? Let’s see.
Hormonal Problems
Hormonal problems, for example, a decrease in testosterone levels (the main male hormone responsible for masculinity and affecting libido), an impaired level of prolactin and some other hormones can worsen the effectiveness of tadalafil, the main active agent of the drug.
Studies conducted in recent years show that a
drop in testosterone levels can lead to decreased performance, decreased lean
body mass and increased body fat, elevated blood pressure and increased risk of
developing heart disease, which in turn can adversely affect erectile function.
In these cases, the mechanisms for reducing
erection are associated with libido, and Cialis-type medications cannot
influence sexual desire. Treatment of
hormonal disorders can normalize the effect of the drug.
Impairment of
Cardiovascular Disease – Possible Cause
There is no evidence that Cialis can lose its
effectiveness over time by itself. However, its effect may decrease if the
cardiovascular condition that caused erectile dysfunction begins to worsen.
In this case, the problem is not in the preparation, but in the progressive disease. If you know that you have any heart disease that may have led to impotence, you should consult a doctor if you notice that tadalafil has not been working satisfactorily.
Causes may include poor control of high blood
pressure (by the way, anti-ED drugs are contraindicated in case of uncontrolled
hypertension), elevated cholesterol, and an increase in excess weight. Solving the problems underlying erectile
disorder will have a positive effect not only on sexual health, but also on
your heart.
Psychological Problems
The deterioration of the drug’s effect may be
due to psychological problems with a partner. If there is coldness and
misunderstanding in the relationship, sexual relations can worsen. In addition,
some men may develop pronounced psychogenic problems that adversely affect the
normal effect of the drug.
The most effective sex therapy is paired family therapy. In addition to sessions with a therapist, partners are required to complete homework in order to achieve positive results.
If Cialis stops
working, you can try switching to another drug. But it is better to analyze the situation
well and / or to make an appointment with a doctor in order to reveal the true
cause of the malfunction. You may have experienced a more serious illness that
requires treatment. Better
safe than sorry…
In online
pharmacies, Viagra for women (Female Pink Viagra) is gaining popularity. What about
Cialis? Is there a female version of “The Weekend Pill”, a record holder for
the duration of the action?
A Couple of Words about
Cialis
These pills
(officially produced by the American company Eli Lilly) are recommended for
adult men suffering from erectile dysfunction. After taking Cialis, a man gets
the desired effect under the conditions of sexual stimulation. The drug can be
used on demand and on a daily basis. When applied on a daily basis, treatment
may give improved effects over time.
Is Female Cialis Available
Officially?
There are
several drugs on the market for the treatment of female sexual dysfunctions. A
few years ago, the American FDA approved flibanserin (G02CX02 (WHO)) for this purpose.
However, the usual male sildenafil also proved to be effective when used by women. Therefore, in online pharmacies you can find such drugs as Lovegra and Female Pink Viagra, which help to increase a lady’s excitement.
Since tadalafil can also be effective in women, Indian companies have released the drug Tadafem. In fact, it is a copy of Lovegry (Viagra) with another active ingredient in the composition. Another drug that has tadalafil in its composition and is intended for ladies is a product called “female Cialis”. This drug is available in our online pharmacy, please find the appropriate section in the product range.
Declared Effects
The manufacturer of this drug claims that it affects the blood circulation, dilating blood vessels in some parts of the body. As a result, it provides an adequate flow of blood to the pelvic organs and increases the production of vaginal lubrication. In addition, the drug can potentially increase sexual desire, making the erogenous zones more sensitive to a partner’s touch. It should be noted that it does not directly affect libido as such, it simply improves the processes of arousal in the body.
How to use?
It is recommended to take Cialis 20-40 minutes before sexual intercourse. To obtain the desired range of effects, it is enough to take 1 pill. The medicine needs to be washed down with water. The maximum dosage per day is 1 tablet, it is better to take a longer break between successive dosages.
Contraindications
Like any
other drug from the group of PDE5 inhibitors, female Cialis has
contraindications:
allergy
to any of the components of the drug (main or auxiliary);
serious
diseases of the heart and vascular system, including uncontrolled arterial
hypertension and severe arterial hypotension;
peptic
ulcer in the period of exacerbation (open phase);
pregnancy,
breastfeeding (in these cases, it is generally necessary to be very selective to
any medication taken and always consult a doctor);
use
of similar drugs, for example, Lovegra;
being
under the age of 18 (minor);
serious
kidney and liver disease;
post-surgery
period.
In order to
avoid the onset of uncontrollable effects and dangerous adverse events (such as
very severe headaches, dizziness, a sharp decrease in pressure) it is
recommended to follow the instructions drug use, that is, overdose is
prohibited.
What Does the Science Say?
According
to Borghi C and Dell’Atti L. (Archivio Italiano di
Urologia e Andrologia, 2017), PDE5 inhibitors can be an efficient option for
many subtypes of sexual disorders in females. Well-known vasoactive agents,
especially tadalafil, showed satisfactory results.
As reported by Ashton AK and Weinstein W (Journal of Sex & Marital Therapy, 2006), females had derived benefit from using 20mg Cialis before anticipated coitus to reverse drug-induced sexual problems (without side effects).
The Bottom Line
Thus, female Cialis really exists. The mechanism of its action is the same as that of female Viagra. But it works longer, providing more sexual spontaneity. However, female sildenafil may be more preferable for some women, as it acts for a shorter period of time, reducing the risk of adverse interactions with other pharmaceutical substances (if a female patient takes other meds). Remember that, as in the case of male anti-ED drugs, the female versions should in no case be combined with nitrates (nitroglycerin, etc.).
It is known that the maximum dosage of the
original Viagra is 100 milligrams of sildenafil. The maximum dosage of branded
Cialis is only 20 mg of tadalafil. However, can these dosages of two drugs be
considered equal in terms of the strength of the effect?
Viagra vs Cialis: What’s the Difference?
We’ve thoroughly analyzed these drugs and
decided to highlight key factors of
differentiation.
Producer. Genuine Viagra is manufactured by Pfizer Inc., a renowned American pharmaceutical company. Original Cialis is produced by Eli Lilly, which is also a US-based pharma giant. However, this difference is not determinative in case of generics. They are produced by less-known Indian, Canadian, and European manufacturers. We would not advise to buy generic drugs from China, as a risk to get a counterfeit is elevated.
Dosage.Viagra comes in three main dosages: 25mg, 50mg, and 100mg. There are four versions of Cialis: 2.5mg, 5mg, 10mg, and 20mg. As you can see, even the minimal dosage of Viagra (25mg) has less pharmaceutical substance than the maximal-dosed Cialis version (20mg).
Appearance. Viagra is supplied as a diamond-shaped blue pill while Cialis is sold in the form of almond-shaped yellow-colored pills. In case of generics, the difference may be another (depending on the product you choose).
Uses. Viagra and Cialis are both used to treat erectile dysfunction. In addition, other drugs with their active agents are used to fight pulmonary arterial hypertension. These are Revatio (sildenafil) and Adcirca (tadalafil). What is more, there are perquisites to assume that Viagra may be also used for urinary symptoms of BPH, however, there is no official approval for such a purpose.
Time of Action. Viagra works for 4-6 hours, in some males the needed effect may be observed within a 12-hour period. Cialis acts much longer (see below).
There may also be other differences, but they are not significant.
What is the Key Feature of Cialis?
The main advantage of Cialis is an increased biological
half-life of the active substance, which is approximately from 17 to 20 hours.
Due to this, the desired effect is guaranteed
within 36 hours after consuming the pill. As we have noted above, the
maximum possible period of action of
Viagra is only 6 hours (rarely 12 hours). Interestingly, this advantage is
achieved without the use of a higher dosage of tadalafil.
For one and a half days, Cialis (or tadalafil) suppresses the production of PDE5 enzyme in the body, causing the cessation of erection. This drug, as well as Viagra, is a selective PDE5 inhibitor. What does it mean? Cialis blocks PDE5 (phosphodiesterase type 5) enzyme more actively, virtually not affecting the rest of useful PDE enzymes. For example, PDE3 is involved in cardiac muscle contraction, vascular smooth muscle and platelet aggregation. The effect of Cialis on this enzyme is 10 thousand times weaker than on PDE5.
Cialis 20mg vs Viagra 100mg: What’s the Best Choice?
These drugs belong to
the same family – PDE5 inhibitors. They also have about the same efficiency: they work in 80-90% of
patients with the highest possible dosage.
However, Cialis is believed to have either a
more concentrated or more potent substance, so it contains a lower dosage than
its main competitor.
However, Cialis 20mg and Viagra 100mg are almost the same in terms of improving erections. Some may get the best effect from Cialis, while others may prefer Viagra. But do not think that Cialis in the 20-milligram dosage is weaker than Viagra and vice versa.
Thus, in terms of dosage strength, these doses
can theoretically be considered identical. But at the same time, they cannot be fully equated. Cialis has
a different half-life, which makes its action time six times longer than that
of Viagra (sildenafil lasts up to 6 hours, while tadalafil provides the desired
effect up to 36 hours). So choosing one or another preparation is generally a
matter of taste. Administering other medications may also influence the choice,
since Cialis lasts longer in the body, consequently, the period of possible
harmful interactions with other drugs becomes longer.
Online pharmacies are a very convenient way to buy the necessary medicines, especiallythose for treating ED. After all, men value their privacy very much and do not want anyone to know about their problems. Unfortunately, the online pharmaceutical market offers many counterfeits that are associated with some health risks.
Counterfeited Drugs in Online Pharmaceutical Market
According to estimates of experts from international organizations, counterfeits account for 40% of the world pharmaceutical market. The WHO believes that on the Internet, part of counterfeit medicines can be up to 50 per cent. Experts say that counterfeiting of medicines has turned into the largest international underground business comparable in scale to drug trafficking, with the only significant difference that no one is insured against the threat of buying counterfeit drug, regardless of social status and income level.
In most cases, counterfeit medicines are not equivalent to the original drugs or generics in terms of quality, effectiveness, or side effects. Examples of counterfeits include widely used drugs, e.g. paracetamol, controlled substances such as human growth hormone, which is often illegally used in sports, and other types of drugs such as Viagra and Cialis. Viagra is counterfeited quite often, because it is a very popular medication among men suffering from erectile dysfunction. At the same time counterfeiters very skillfully forge the original medication. They give the tablet the same shape as original Viagra, put the same markings and offer medicines in the same package.
Several years ago, Pfizer Inc. (the developer of genuine Viagra) conducted its own investigation. Experts of this company bought Viagra from various sites, including suspicious ones, which claimed that they were selling the original Pfizer medicine.
Here is what they found in the counterfeited Viagra and other drugs:
blue printer ink (counterfeiters have used it to give the tablets a blue color);
amphetamines;
Metronidazole*, an antibiotic that can cause gastrointestinal upset in large dosages;
increased dosages of the active substance, which increases the risk of side effects and can cause harm to the body;
binding agents, for example, drywall, which prevent the absorption of the tablet in the digestive tract;
toxic substances, for example, road paint and rat poison, which can cause poisoning of the body and even lead to death;
a completely different medication that has a different effect on the body and potential side effects.
*For more information about Flagyl ER (Metronidazole), please visit this page: Coming Soon!
Dangers of Counterfeited Viagra Use
There are several types of counterfeit medicines on the pharmaceutical market:
“Empty” drugs. They are usually not dangerous, but they do not give the desired effect. Counterfeiters add empty fillers to them and that’s it. Although in some cases they can work by analogy with placebo.
Medications that mimic treatment. They contain some active ingredients (for example, extracts of some plants), but these ingredients are cheaper and much less effective. They can have a curative effect, but they do not work as well as sildenafil (the basic component of Viagra).
Medicines with a low dose of active agent. The minimum dosage of Viagra is 25 mg, it is also available in 50 mg and 100 mg dosages. Some counterfeiters may decrease the dosage of the active substance. As a result, the medication may not work or exert a weaker effect.
Medications with increased dosage. It is not known why some scammers add more active substance than necessary. However, such counterfeits exist on the pharmaceutical market. They can have a stronger effect but their use is associated with a much higher risk of side effects.
Meds containing wrong ingredients. This is a dangerous kind of fakes when manufacturers add to the tablets cheap antibiotics or something else instead of sildenafil and other active substances. Such “medicines” can be dangerous to health because a person may have an allergy to the ingredients actually contained in a counterfeit medication. In addition, such products can cause unpredictable side effects and react unpredictably with other medicines.
Experts believe that all falsifications are potentially dangerous for health, since they are not subject to quality control required for legal medicines.
However, the most dangerous thing is when counterfeit medicines contain harmful chemical ingredients (examples of such ingredients have been described above). In this case, the patient will not only get the desired effect, but will also do harm to their health. So be very careful when buying Viagra on the Internet.
How to Avoid Counterfeits When Buying Viagra?
When you buy medicines on the Internet, evaluate the appearance of the website. Also, check if the site has an SSL security certificate and if there is a form for contacting the support service. In addition, it would not be superfluous to read reviews of users who have already bought medicines in this online pharmacy. If you see a kind of original medicine at a low price, it is most likely a fake. Legal generics do not claim that they are originals, they can have a different form.
By adhering to these simple rules, you can avoid fake Viagra on the Internet.
Another tip: you can get free samples of Viagra (Canadian Health Care Mall provides such an opportunity) and check their quality. If you are satisfied, you can order in this pharmacy in the future. My Canadian Pharmacy guarantees high quality of anti-ED medications.
You come to the drugstore with the prescription list, but instead of the preparation which is written out by the doctor with a famous trade mark or brand, the pharmaceutist offers you other medicine of similar appointment, explaining it to that your insurance pays only this “generic”. Thus he claims that meanwhile there is no difference neither in the mechanism and force of action, nor in side effects. It is clear that unexpected replacement causes some suspicions though there is in this situation and the pleasant moment namely generics cost significantly less. And this benefit because of prolonging prices increase becomes more noticeable.
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