How Effective Is Cialis for Benign Prostatic Hyperplasia Treatment?

Besides erectile dysfunction, Cialis (tadalafil) is used against prostate enlargement, the official name of which is benign prostatic hyperplasia. This is the only product from the family of PDE5 inhibitors that has been officially approved for use for these purposes and that can be securely taken on a daily basis (thanks to minor dosages of the active ingredient, in contrary to other PDE5i meds).

What is BPH and What Symptoms Can It Cause?

Benign prostate hyperplasia (BPH) is an enlargement of the gland in size. As a rule, the probability of getting sick with BPH increases with age. Such non-encouraging statistics are linked to age-related hormonal fluctuations. When the disease develops, a benign tumor in the prostate increases in size and leads to the appearance of the following unpleasant symptoms:

  • frequent urination
  • urination at night, which leads to recurring visits to the toilet at night and the incapability to sleep well (according to the International Continence Society this condition is called nocturia)
  • weakening of stream pressure, weak and intermittent stream of urine
  • the need to immediately urinate after the urge (the so-called imperative urges)
  • feeling of incomplete emptying of the bladder
  • the need for straining when urinating
  • urinary incontinence with overflowing bladder
benign prostate enlargement treatment

How Does Cialis Work in This Case?

In impotence, this medication works by increasing the level of the cGMP substance through an inhibitory effect on the cGMP-degrading enzyme called phosphodiesterase type 5 (shortly PDE5). cGMP increasingly boosts blood flow to the genitals. Also, this substance helps to relax muscle tissues in other places the body, including bladder and prostate, relieving tension. This may alleviate the relief of symptoms of BPH in patients.

The usual advised dosage of Cialis for BPH is 5 milligrams.

A closely related topic (must read): Cialis Daily vs. Regular Cialis

How Long Does It Take for Cialis to Remove the Symptoms of BPH?

According to information on the official website of Cialis (which was maintained by the manufacturer but is now closed, most likely because the company had lost the exclusive right to manufacture drugs based on tadalafil), it can take up to 1 month for the patient to feel an easement in symptoms of benign prostatic hyperplasia. However, results can be seen in just two weeks.

cialis bph study

What do scientists think about this? Thus, Kevin T. McVary (MD) in an article published in The Journal of Urology in 2015 indicates that 60–70% of men who took part in the experimentation and consumed Cialis had a clinical improvement in their urinary symptoms.

However, approximately 50 percent of respondents reported improvement after 1 week of treatment and approximately 70% felt relief by 4-week ‘deadline’. Thus, these data almost completely coincide with information from the developers of the drug. Mr. McVary reasonably offered a thirty-day trial period for the use of the medication for these purposes. If after a month there is no adequate response to therapy, most likely the positive effect will not appear in the future, so one need to look for an alternative.

Limitations for Use

There are several absolute contraindications to the administration of Cialis:

  • the consumption of medications called nitrates, which are often prescribed to combat chest pain caused by heart angina; this is because a combination of tadalafil and a nitrate-containing drug (such as nitroglycerin or isosorbide dinitrate) can lead to an unsafe and sometimes even fatal drop in blood pressure
  • the use of guanylate cyclase stimulant drugs, such as Adempas, which are designed to combat pulmonary hypertension, for the identical reasons as indicated in the previous bulleted point (a possible blood pressure plummeting)
  • allergic to tadalafil or any of the auxiliary components of the medication

An important point: previously, the manufacturer of the drug (Eli Lilly) recommended using Cialis in five-milligram dose for handling urinary symptoms (also known as LUTS) of BPH which coexists with erection disorder. But the drug can also be useful as a remedy to treat exclusively BPH (after medical advice).

cialis 5 mg bph

Are Side Effects Possible?

Like any other medicinal remedy, this one can cause a number of side effects. Dangerous interplay can sometimes occur if the drug is combined with other medicines and alcoholic refreshments. Consult your doctor if you are administering other prescription drugs. Common adverse events include headaches, upset stomach, and abdominal pain. Cold symptoms and facial flushing may also occur. Typically, these symptoms do not require medical attention. Side effects are infrequent and transitory if the drug is administered in recommended doses, moreover, adequacy and reliableness of medications prescribed is a overriding thing, and that is expressly what this medication guarantees. It had been tested for several years afore getting approval from the FDA.

Summary

Cialis is effective in most cases of unpleasant symptoms of BPH affecting the urinary system. However, a relatively small proportion of patients may not feel proper effectiveness. Then they need to ask the doctor to replace the medication with a suitable substitute.

7 Myths about Premature Ejaculation and Their Debunking

As reported by scientists at University of North Carolina, premature ejaculation (abbreviated PE) is likely the most prevalent sexual malfunction in men. That makes sense considering that many young males may suffer from this disorder, not to mention adults. It is known that in every age group about one third of men suffer from this distressing disorder which may impact and even ruin relationships. Despite high availability of medical information, the situation has engendered contradictory and strange misbeliefs like that all males with PE may develop severe anxiety disorders or that the risk to have PE decreases with age.

1. Premature Ejaculation and Erectile Dysfunction Are Equipollent Things

These two disorders are unreservedly dissimilar. When a male has erectile dysfunction (ED), he has troubles with getting or keeping erection at the level which is enough for normal sex. PE, on the other hand, refers to situations when a man is unable to control ejaculation, but the ability to achieve erections is saved. Sometimes, ED and PE coexist.

premature ejaculation psychological

2. Premature Ejaculation is Caused by Nervousness

While many occasions may (partially or wholly) have psychoemotional nature, a lot of cases are caused by oversensitive glans penis which have no relation to psychological component. Males with glans’ oversensitivity are considered to have low ejaculatory threshold.

3. Men Have PE If They Ejaculate Within 2 Min After Penetration

International guidelines on PE define it as when a male person ejaculates within 60 seconds of entering his partner. However, the average duration of sexual intercourse is just 5.4 minutes (across all couples). But that’s not the point. Males who last 2 minutes or longer may also insist that they have the disorder. PE may happen occasionally, the key thing here is ability or inability to control the ejaculation.

alcohol and premature ejaculation

4. Alcohol, Marijuana, and Antidepressants Are Good Tools to Combat the Disorder

Inhibition of sensitivity and ejaculation may be aftereffect of these drugs, but one should take in account other side effects that may be caused. Drug and alcohol abuse is related to libido worsening, erectile disorders, and testosterone level decrease.

As for medical support, guys may use antidepressants but they should be aware that this class of drugs may cause some side effects including sexual ones like lessened libidinal characteristics. Moreover, not all remedies against depression are suitable. There is the only oral medication approved for PE (see information about it in the ending section of this article). Plus, in any case you should take meds in moderate dosage, not for long period of time, and under doctor’s supervision.

5. Ejaculation is a Physiological Process that Cannot be Controlled

You most likely know such thing as bladder control, it’s when you stop urine flow from being released (the-so called toilet training). If one learns how to control ejaculation (and this is definitely possible) he is unlikely to forget this capability. That’s why Kegel exercises may be advantageous for treating PE, as they help to strengthen the urinary sphincter and musculature which is responsible for control of ejaculatory process.

Read our article on this topic: Exercises for Better Sex

6. Possibility to Have PE Decreases with Age

Many youngsters suffer from ED, that’s true. But, surprisingly, the prevalence of the disorders remains at approximately the same level to the age of fifty. Then it remarkably climbs up before calming down and decreasing. For instance, with accordance to a large-scale study by Korean scientists published in Asian Journal of Andrology (2010), only about 15 per cent of answerers in the age over fifty had complained of premature ejaculation.

premature ejaculation drugs

7. A Semi-Myth – PE Has Become “Medicalized”

This is a not common but definitely existing myth. Many people think that any male with the disorder can easily use a magic pill which will cure the problem. In fact, according to research, only 12% of respondents had used medical treatments. That’s actually an issue, because the contemporary medicine can offer decent solutions for premature ejaculation, like Priligy (Vriligy) which contains dapoxetine. But in reality, not all men are aware of this treating method. You can check the assortment of our products and order this medication without obstacles.

The medication was initially studied as an antidepressant but then healthcare professionals revealed unsuspected dapoxetine characteristics and switched to a different dimension of its use, i.e. therapy of premature ejaculation. At the moment, this is the only medication approved by regulatory bodies of different countries specifically for PE treatment.

Foods that Can Help With Premature Ejaculation

If you suffer from premature ejaculation (PE), you will certainly wonder how to prolong the duration of sexual intercourse. There are several pharmaceuticals that help treat premature ejaculation, there are also some wholesome products, and usually a combination of methods works well.

Below we will tell you about common products with beneficial properties for men with PE.

1. Onion seeds. Green onion is considered an aphrodisiac, although before intimacy it is certainly not desirable to eat it because of the pronounced smell. However, to get a beneficial effect, you needn’t eat onion bulbs or leaves. Just crush the black seeds of this plant and mix them with water. The scheme of intake: eat three times a day before meals. The drug has a positive effect on libido and improves sexual stamina.

indian ginseng

2. Ashwagandha (Indian Ginseng). This plant has been used for centuries in Ayurvedic practice. Ashwagandha blooms with small greenish-white flowers, from which red fleshy berries covered with red shiny cup-lanterns develop. Indian ginseng improves mental abilities and helps increase sexual desire. Ashwagandha is also widely used as a natural way to treat erectile dysfunction.

3. Garlic. It is known for its anti-inflammatory and antibacterial properties as well as a means of preventing colds and flu. However, it is also a powerful aphrodisiac that can be helpful in enhancing sexual stamina. If you do not like the pronounced taste of fresh garlic, you can use a dried product or even special dietary supplements based on this plant.

products for pe asparagus

4. Asparagus. This is a delicious vegetable in the form of the sprouts appearing in early spring. It is believed that asparagus can help strengthen control over the penis muscles and thereby reduce the symptoms of premature ejaculation. A good recipe: boil asparagus roots in milk and take this drink twice a day.

5. Ladies’ fingers. Abelmoschus esculentus (ladies’ fingers ) is a leguminous vegetable whose fruit tastes like a bean and zucchini at the same time, so its use in cooking is quite wide. However, not all people even know about its existence, but they should, because ladies’ fingers is a good remedy for premature ejaculation. You can cook various dishes from it and include them in your daily diet or take it in powder form on a daily basis (without the risk of side effects).

6. Carrot. This is not just a delicious vegetable, carrots or carrot juice can be used to combat premature orgasm in men. This is due to the positive effect of the vegetable on libido thanks for its rich vitamin and microelement composition. Improving libidinal characteristics can help a man better control the moment of onset of ejaculation.

What Foods Should be Excluded from a Diet?

It is better to exclude or minimize the use of coffee and caffeine-containing products, as they have a stimulating effect on the central nervous system, which can lead to over-excitation and too fast ejaculation in men who are prone to this. It would also be a good idea to eat less chocolate and chili.

Male Diseases and Conditions in Urology

According to statistics, during medical examination chronic prostatitis is detected in 50% of men aged 20-50, and benign prostatic hyperplasia – in 40% of men over the age of 50. If we take into account erectile dysfunction, we can confidently say that diseases of this nature are the most common in men.

Although it is impossible to broadly cover all male urological diseases, below we will try to provide generalized information regarding the types, symptoms and methods of treatment of this group of medical problems.

urological diseases in males

Types of Diseases in Urology

The diseases of this category in men include:

  • Benign prostatic hyperplasia (adenoma). This is a non-cancerous tumor, usually this disease occurs in men older than 30-35. It is characterized by unpleasant urinary symptoms, including frequent urination, frequent visits to the toilet at night (nocturia), a feeling of incomplete emptying of the bladder, dribbling during urination, weak urine stream, etc.
  • Prostatitis. This is the most famous disease of the prostate gland. It can occur at any age, but the risk of getting sick increases with age, especially with a sedentary lifestyle. Prostatitis can be acute and chronic. There are several symptoms of prostatitis: increased anxiety, nervousness, which are caused by patients’ focusing attention on their condition; disorders of the body’s sexual function (erectile dysfunction), disorders of the genitourinary system (problems with urination), as well as pain in the lower abdomen.
  • Urethritis. This is a urethra disease , which is triggered by canal wall damage caused by various kinds of bacteria and viruses. Urethritis can occur due to hypothermia, sexual infection, trauma, improper diet and water intake schedule (insufficient fluid intake), chronic inflammatory processes in other parts of the body, excessive physical exertion and subsequent weakening of the body.
  • Erectile Dysfunction (ED). This disorder is characterized by the inability to achieve a normal erection. The reasons can be different, from psychogenic to organic ones (vascular damage, impaired blood flow, etc.). Men often ask the question – What kind of doctor is involved in the treatment of erectile dysfunction? In this case, most likely a urologist will be a team leader. If the ailment is caused by hormonal disruptions, you need to contact an endocrinologist. A cardiologist may also intervene, since ED is often an early predictor of cardiovascular disease. You might be interested in: Can ED Develop in Young Men?
  • Cystitis. This is an inflammatory disease of the bladder. Men suffer from this disease less frequently than women, because their urethra is longer and narrower than in women, which reduces the risk of infection inside the bladder. Often male cystitis is secondary; it develops due to the presence of problems with the prostate gland.
  • Epididymitis. This disease is associated with the testis appendage, it is characterized by the inflammatory process, swelling, and hyperemia (severe redness) of the scrotum. Sometimes it is accompanied by inflammation of the testicle itself (orchiepididymitis). Usually this disease is one-sided, but bilateral cases also occur. In general, infections (mainly sexually transmitted ones) are the cause of epididymitis.
uti in men
UTI stands for urinary tract infections and is also known as cystitis

Symptoms of Urological Diseases in Men

Even irregular and especially constant manifestation of the following symptoms should alert you:

  • the appearance of rashes, redness in the penis and testicles;
  • pain, itching, burning in the mucous membrane of the penis and / or urethra;
  • difficult or too frequent urination, other problems with the bladder;
  • pain in the perineum and lower abdomen;
  • discomfort that occurs during sexual intercourse or its end;
  • inability to get a normal erection;
  • bloody or mucous discharge, unpleasant odor.

The above symptoms may indicate the presence of an inflammatory disease or a sexually transmitted one.

A related topic: Preventing Erectile Dysfunction Wisely: Useful Tips

Treatment Methods

Specific drugs and other methods depend on the urological disease. Often men do not want to see a doctor because of embarrassment and mixed feelings, since urological ailments are quite intimate. They hope that the problem will go away on its own, but often only exacerbate the situation. Usually, urologists are tactful and delicate when talking to patients. Moreover, do not forget that you are not alone with this problem, as millions of patients around the world are faced with urological diseases.

Here are some examples of treatment. A popular remedy for prostatic hyperplasia is Cialis (tadalafil). It eliminates the symptoms of BPH and erectile dysfunction at the same time, given that these diseases are often found in combination. This is a very beneficial advantage of the yellow pill.

Diabetes and Obesity: Dangerous Inter-Correlation and Prevention Tips

According to a 2016 report by Margaret Chan, Director General of the World Health Organization, 800 million people in the world are starving, while in some countries around 70 percent of the population is overweight or obese. However, even in middle- and low-income countries, people can be overweight because they often eat in fast-food restaurants abounding in poor areas.

Obesity increases the risk of many cardiovascular diseases and certain types of cancer. However, the most obvious role of being overweight is in the development of diabetes. In many ways, the prevalence of this metabolic disorder (which is fraught with very dangerous complications) is up to 9% among adults worldwide.

So, how are overweight and diabetes related and what prevention tips exist?

diabetes and obesity

Link Between Diabetes and Obesity

The link between obesity and diabetes has been known for a long time. An ancient treatise of Indo-Tibetan medicine of the VIII century noted that diabetes was more common in overweight patients who ate unhealthy food and led an inactive lifestyle. However, the French doctor A. Bouchard was the first person who explained the close relationship between obesity and diabetes at the scientific medical level in the second half of the 19th century.

If you are overweight, the cells begin to develop increased insulin resistance while the pancreas can work properly. Increased insulin resistance leads to many metabolic disorders.

Obesity is known to provoke inflammation, which in turn leads to metabolic problems. But the mechanism of this process itself is a bit confusing.

In people with obesity, many cells die and collapse, and as a result, a lot of cellular DNA enters the bloodstream (this has been confirmed by studies). Moreover, DNA from dead cells is often found in immune cells called macrophages that move around adipose tissue. Then, the synthesis of TLR9 receptor (a special protein) is enhanced in the cells. This leads to the launch of inflammatory reactions, which are a powerful weapon against bacteria, but in this case they have a devastating effect and can cause diabetic symptoms. This is not the only mechanism, but the fact remains that being overweight is a huge factor in the development of diabetes. In addition, people with diabetes sometimes tend to have more chances of developing obesity.

Read our article: Life with Diabetes Can Be Fulfilling

How to Prevent? Useful Tips

Obesity is known to be the result of a positive energy balance. High-calorie diets rich in fat, simple sugar (e.g. cakes, muffins, donuts, chocolate, etc.) and low in fiber, reduced physical activity lead to an imbalance of energy and the deposition of excess triglycerides in adipose tissue. Moreover, the level of triglycerides in the blood rises, which negatively affects the state of blood vessels. To ensure sustainable weight loss, it is necessary to create a negative energy balance, and in general, to change the way of life.

diet for diabetes

Therefore, in order to prevent obesity and thus reduce the risk of diabetes (obesity is not the only reason but one of the key ones), you need to radically change the principles of nutrition.

The basis of your diet should be vegetables, fruit, whole grains and low-fat sources of protein (such as lean meat and fish). But you can suffer from excess weight, even eating properly. Therefore, to lose weight you need to create a negative energy balance. To achieve this goal, your body needs to spend more calories than it has received. Of course, you need to reduce the amount of food consumed and lead a mobile lifestyle. The best option is to go to the gym on a regular basis. It is not necessary to work with weights (sometimes it can be undesirable or harmful), but you can choose from hundreds of sports activities. If you cannot attend a gym or some kind of sports section, just walk a lot. Long walking is a great fat burning tool (just don’t take biscuits with you).

Pull yourself together, work out the right regimen and your body will thank you.

What is Andropause (Male Menopause) and Does It Really Exist?

The number of studies related to the aging of the body has been gradually increasing in recent years. This is due both to the development of medicine (as a science) and to an increase in life expectancy throughout the world. As a rule, aging marks a decrease in the reproductive abilities of the body. Thus, in women, the onset of menopause means the end of the reproductive period. What about gentlemen? Can they experience ‘andropause’ or ‘male menopause’?

Features of Aging and Its Effect on Hormones in the Male Body

‘Andropause’ begins to manifest slowly in men. A man does not receive (feel) a definite signal about the onset of ‘andropause’. There is no specific factor that can indicate this intermediate stage, so men often do not attach importance to the deterioration of their well-being and various ailments in this period. The first decrease in testosterone synthesis begins after the age of 30. Many men begin to lose healthy erectile function after 40, the prevalence of hormonal problems increases with age. In men of the same age, testosterone levels are different. It depends on many factors, such as lifestyle, bad habits, heredity, the presence of concomitant diseases. Say, in case of arterial hypertension, coronary heart disease, some other heart diseases, diabetes mellitus, etc., testosterone levels are 10-15% lower than in healthy people of the same age.

testosterone deficiency syndrome

‘Andropause’ term refers to a decrease in testosterone levels, it is used by many experts, but some doctors believe that it is incorrect.

However, if a man is generally healthy, his body is capable of producing sperm even at the age of 80. There are cases when a man became a father at 96 years old. For comparison: the oldest mother in the world gave birth at 69 years old (this was a unique case).

Age Androgen Deficiency – Late-Onset Hypogonadism

Doctors often use the medical term late-onset hypogonadism (testosterone deficiency syndrome) to denote menopause in men. This diagnosis includes a decrease in testosterone confirmed by laboratory tests, which is accompanied by the corresponding symptoms (after all, testosterone is responsible for many functions in the body):

  • decreased libido (sex drive)
  • ejaculation disorders, such as delayed orgasm or dry orgasm
  • increase in the amount of adipose tissue, female type fat deposition
  • deterioration of bone tissue condition
  • decline in vitality, constant fatigue
  • irritability
  • decreased focus (attention)
  • nervousness
  • depressive disorders

You might be interested in: ED and Depression: Often Coexist but Can be Overcome

low testosterone diagnosis

This disorder can be treated with testosterone preparations, but if it is important for the patient to maintain fertility (the possibility of fertilization), other treatment methods should be preferred, since the constant receiving of exogenous testosterone leads to inhibition of the production of endogenous (internal) hormone by the body.

As you can see, a decrease in testosterone affects not only sexual function. Therefore, serious medical intervention and careful approach are necessary with a pronounced decrease.

Propecia for Women – Can Finasteride Be Used by Females?

Hair loss is a widespread problem which might affect not only men. Some women also suffer from this condition, naturally, they want to find efficient and safe remedy. Propecia is a male medication which helps to fight baldness. Can women benefit from this?

Finasteride Indications

Finasteride is a component of drugs used to treat prostatic hyperplasia and baldness. The drug manufactured under the brand name Propecia, is specifically designed for the treatment of male pattern baldness (androgenic type). It was originally created to treat prostate enlargement, but researchers noticed that the subjects also experienced increased hair growth, which led to the use of finasteride to combat baldness.

finasteride for women

Contraindications

Finasteride has contraindications for use with:

  • hypersensitivity to the components of the drug
  • malignant tumors in the prostate gland
  • obstruction of the channels of the urine drainage
  • pregnancy or desire to become pregnant
  • negative reaction of the body to the use of finasteride
  • severe liver pathologies and symptoms of hepatic encephalopathy.

The administration of this therapeutic agent is not indicated for use by patients undergoing hemodialysis.

Females of reproductive age, and especially women during the pregnancy period, should completely abandon the use of the medication. It should be remembered that powder or crushed fragments of a tablet containing finasteride can enter the bloodstream through the pores of the skin and cause irreparable harm to the fetus, this especially concerns intrauterine development of male infants. It should be borne in mind that the therapeutic effect of this medication is associated with blocking the synthesis of dihydrotesterone (DHT), which is responsible for the formation of boys’ genitals in the womb.

Can Women Use Finasteride? Have Clinical Trials Been Performed?

Finasteride official instructions contain no information about possibility of using finasteride by women (they only contain precaution information, which was described above).

female baldness

There were several studies in which scientists evaluated the efficiency and use of the medication in women. The latest review was made by A.C. Hu et al. (International Journal of Dermatology, 2019), the scientists reported about 65 studies with participation of more than 2,600 female patients. However, according to the scientists’ opinion, future long-term studies are needed to fully evaluate prospects of finasteride use in female population.

R. Oliveira-Soares and others (International Journal of Trichology, 2018) concluded that finasteride is useful n premenopausal patients with female pattern hair loss. However, they had some concerns with regard to eventual long-term side effects of the pharmaceutical.

Conclusion

Thus, if you are a woman and plan to have children, finasteride is definitely contraindicated for you. This medication is not yet officially approved for use by women. Middle-aged women who don’t plan pregnancy in the future can potentially use this medicine (as there are some scientific confirmations). Talk your physician. However, it is probably better to search for safer solutions.

Buspar for Anxiety: Mechanism of Action, Dosage, Reviews

Anxiety disorders are the most prevalent psychiatric disorders in the world. Scientists have reported that these disorders may be underrecognized and undertreated. Treatment is necessary when a person experiences severe distress and/or complications associated with the disorder. Buspar has proved its efficiency in resultative fighting against anxiety.

Buspar’s Mechanism of Action

The main active ingredient of the drug is buspirone. This is an anxiolytic substance that differs in pharmacological properties from benzodiazepines, barbiturates and other sedative and hypnotic medical remedies. Studies have shown that buspirone has a high affinity for 5-hydroxytryptamine 1A receptors and a moderately pronounced affinity for dopamine D2 receptors in the brain. In simple words, Buspar affects chemicals that can be unbalanced in people with anxiety.

The effect of the drug occurs gradually; you will see the first results in 1-2 weeks. The maximum effect is achieved after 4 weeks.

Buspar does not cause addiction, it can be canceled without negative consequences for mental health. Patients cannot develop tolerance to this pharmaceutical substance.

busiron for anxiety

The drug helps to cope with the following diseases / conditions:

  • generalized anxiety disorder
  • vegetative-vascular dystonia, a type of dysautonomia, which affects vascular system
  • panic disorders
  • alcohol withdrawal syndrome (as a substituent of complex therapy)
  • depression (as an additional remedy in the therapy)

The use of Buspar leads to complete remission. However, withdrawal of the drug may lead to a return of symptoms.

The medication can cause a number of side effects, including restless legs syndrome (an uncontrollable urge to move the legs), dizziness, nausea, headache, and increased irritability. It is known that some patients with psychological / psychiatric disorders are prone to suicide. Fortunately, Buspar overdose is not enough to execute suicidal intentions. It is typically resolves with full recovery. However, as stated by Tyler K. Wilson and Jayson Tripp (StatPearls article, last updated February 2019), the risk of additional drug overdose exists, so relatives and healthcare experts should also investigate if a patient has administered extra medications.

It is important: the drug is not intended to treat anxiety symptoms caused by everyday stress or a stressful situation. In such cases, regular rest and herbal remedies will help to overcome the problem. Therefore, if you are simply very tired at work and have experienced stress due to bad words of your boss, do not take Buspar. It is intended for more serious cases.

Buspar Dosage, Features of Use

It is usually recommended to start therapy with 15 mg twice a day. Every 2-3 days, increase the dosage by 5 mg / day, until the desired effect is achieved, which should appear in the period up to 14 days.

The maximum dose of the drug is 60 mg / day, an increase in dose is associated with an elevated risk of side effects. The usual therapeutic dose is 20-30 mg / day. The daily dose should be divided into 2-3 portions.

The product is offered in 5mg–30mg dosage range.

Eating food can slow the absorption of the drug in the gastrointestinal tract.

If the medication did not start working after the expiration of the expected “deadline”, you need to consult a doctor and choose another medical remedy, such as benzodiazepine or an antidepressant.

An interesting stuff: Erectile Dysfunction and Depression: Often Coexist but Can be Overcome

buspar reviews

Buspirone Reviews

There are many negative reviews about buspirone on the Internet, but such a situation this is often due to the fact that people do not have the patience to administer the pills for a long period (as mentioned above, it takes 1-2 weeks for the effect to occur) or simply they don’t have proper information about Buspirone administration. Other people write on forums that the medicine reduces sociopathy, increases interest in various activities. For some, a work phone call to another person is an excruciation, but dissolving the tablet eliminates the problem.

How Does Zetia Work? Short Overview of this Lipid-Lowering Agent

Coronary heart disease (CHD) is one of the dominant causes of deaths in adults in the United States. CHD is linked to elevated levels of “bad” cholesterol and decreased rates of “good” chol. Proper treatment should include nutrition adjustments, physical exercises (at least long-lasting walking), and bodyweight loss. However, medication therapy may be a requirement.

Lowering Lipids in the Blood with Zetia

There are many medications that helps to decrease cholesterol in the bloodstream. Among them are bile acid sequestrants, statins, fibric acids, etc. However, there is a unique drug which is distinct from others. Ezetimibe (trade name Zetia) has no inhibitory effect on cholesterol production by the liver, it also doesn’t accelerate excretion of bile acid.

zetia generic

The medication localizes in the intestine and block absorption of cholesterol & some plant-based sterols. Ingestion of high-fat food has no influence on the bioavailability of Zetia (but this doesn’t mean that you can overeat French fries, burgers, cheese and other food with high content of fat, scroll down to know why).

Healthcare specialists typically prescribed Zetia (and clinical studies are also centered on the combination therapy), but monotherapy is also possible. According to the UK scientists Daniel Hammersley and Mark Signy (Western Sussex Hospitals NHS Trust, 2017), one-type treatment may be applied in the following cases:

  • treatment of primary hypercholesterolaemia in persons with contraindications to statin administration
  • hypercholesterolaemia in folks who cannot tolerate statin pharmaceuticals

Effect of Ezetimibe: Scientific Data

IMPROVE-IT trial performed by dozens of investigators and 2574 collaborators (published in 2015) showed Zetia substantially decreased incidence of severe cardiovascular events in people with cardiovascular diseases and low rates of “good” cholesterol. Moreover, incremental decreasing of cholesterol to rates below previous targets which were measured by doctors provided extra benefits.

According to American researchers Jigna Patel and others (Baylor University Medical Center, 2003), coadministration of Zetia plus lovastatin (Mevacor) showed greater effectiveness than lovastatin alone or ezetimibe alone. The combotherapy provided −39% reduction, while lovastatin monotherapy caused −25% decrease and Zetia led to just −19% reduction.

Hence it can be concluded Zetia provides less pronounced effect when used as monotherapy. Conjunction with statins is more efficient, however, this option may be unsuitable for some individuals.

When Is Zetia Contraindicated? What Are Potential Side Effects?

The medicine has high safety profile and is usually well-tolerated in different subgroups of patients. Nonetheless, as in case with any pharmaceutical product, Zetia has several contraindications, including:

  • increased sensitivity to principal or auxiliary components (fillers) of the drug
  • moderate of severe liver insufficiency
  • active liver disease (when combined with a statin medication)
  • pregnancy or breastfeeding (in combination with statins)

Sometimes, patients may experience side effects:

  • liver damage and disorders (especially when the drug is coadministered with statins)
  • muscle pain
  • weakness and tenderness
  • allergic reactions, such as itching, rash, dizziness, and trouble breathing (allergy is rarely observed)
healthy diet for cholesterol

Is It Enough for Successful Treatment?

No, just taking Zetia is not enough for adequate therapy of increased cholesterol. Before starting treatment, patients should switch to an appropriate hypocholesterolemic diet and adhere to this diet during the entire period of therapy. The diet should be based on the following principles:

  • limiting fried food
  • choosing low-fat milk and dairy products
  • eating more fruits and vegetables
  • consuming whole-grained food, poultry, lean fish, nuts and beans
  • curbing soft beverages and sugary food

In addition, scientists have revealed food and food supplies with hypocholesterolemic effects. As stated by Ruitang Deng (University of Rhode Island, 2009), these include fiber or polysaccharides, soy protein, phytoestrogens, and probiotic bacteria (it was claimed that additional studies are needed to evaluate efficacy and safety of probiotics and anti-cholesterol agents).

A related topic by Canadian Health&Care Mall experts: Treatment Diabetes and Overweight

Can High Cholesterol Medications Cause Erectile Dysfunction (ED)?

Healthcare experts are adamant high cholesterol levels are harmful for the health. There are many causes of elevation, but anyway patients who have faced such a problem need an appropriate treatment. Mercifully, there are many medications that really work by decreasing chol levels through different mechanism. There is one awkward moment: some of them might cause problems with male potency.

Side Effects of Medicines and Erectile Dysfunction

ED might be induced by organic and psychogenic factors. Some medicines belong to possible organic causes. The list of potential offenders is extensive, so we will name only some groups with examples:

statins side effects
  • diuretics and high arterial pressure medications (Vasotec, Capoten, Tenormin)
  • anti-anxiety drugs and antidepressants (Zoloft, Prozac, Serax)
  • antihistamines (Antivert, Vistaril)
  • antiarrythmic drugs (Norpace)
  • medications for Parkinson’s disease treatment (Biperiden)
  • NSAIDs (Naproxen)
  • remedies for treating elevated cholesterol rates (Lipitor)

By the way, ED may be caused by diabetes. Read our comprehensive article:

Diabetes-Induced Erectile Dysfunction: Prevention and Treatment

A Short Overview of High-Chol Medications

Before taking any medication, first and foremost, you need to have a medical consultation and determine rates of cholesterol in the body. Well, how to quantify level of cholesterol in the blood? There are special blood tests, which are available in many clinics. It is recommended to regularly undergo them, because people with high cholesterol levels may have absolutely no symptoms.

high cholesterol and erectile dysfunction

Statins are the most prescribed medications for treating the condition. This subgroup of anti-chol pharmaceuticals includes Lipitor, Fluvastatin, Pravastatin, and Lovastatin. They inhibit cholesterol synthesis by the liver. This leads to a decrease in amount of the so-called “bad cholesterol” in the blood. However, statin drugs cannot destroy already formed plaques in vessels.

There are also other types of high-chol medications, however, we will pay more attention to statins, as they have been associated with unpleasant side effects for men’s health.

Can High Cholesterol Medications (Statins) Lead to ED in Men?

Erectile dysfunction is not a widespread effect, and it is even not indicated in many medical articles describing statins. However, links to ED were found in several scientific studies.

Let’s analyze some of them. Xiang Cai, Ye Tian et al., Chinese researchers, reported in 2014 that treatment with statins might decrease testosterone and aggravate impotence symptoms. Testosterone is an essential hormone for healthy sex drive and its reduction might be fatal for sexual life of males who already suffer from ED.

However, as they say, nothing is bad without being good for something. Other studies show statins might actually treat ED. For example, John B. Kostis and Jeanne M. Dobrzynski at Rutgers Robert Wood Johnson Medical School (2019) studied a large array of data and stated: small improvement in erectile function is observed with statins. Impotence may be partially caused by high cholesterol, so statin meds can help to eliminate an underlying cause. Hence, it is not a good idea to abandon the medication intake, check your healthcare provider first.