Active Ingredient

Alfacalcidol

Alfacalcidol is a type of vitamin D used to help balance calcium levels in the body. It is commonly used in situations where the body has difficulty maintaining proper calcium levels due to kidney or parathyroid gland issues.

This medication is particularly beneficial for individuals with certain bone disorders or imbalances in calcium metabolism.

Written By Douglas C. Goldberg, MD

Reviewed By Philip Schein, MD

Last Updated 28 Nov 2025

Available Alfacalcidol Brands

Alfacip

Strengths 0.5 mcg, 0.25 mcg

Alfacalcidol Uses

Alfacalcidol is used to treat or prevent conditions related to calcium imbalance.

Chronic kidney disease-related bone disorders
Hypoparathyroidism
Rickets
Osteomalacia
Management of low calcium levels in the blood

How Alfacalcidol Works

Alfacalcidol works by converting into an active form of vitamin D in the body. This active form helps improve the absorption of calcium from the gut.

By doing so, it aids in maintaining healthy bones and proper calcium levels in the blood. It is particularly useful when the kidneys or parathyroid glands are not functioning optimally.

Common side effects of Alfacalcidol

Not everyone experiences side effects with Alfacalcidol, and many are mild and temporary.

Nausea
Vomiting
Abdominal pain
Loss of appetite
Constipation
Headache
Dizziness
Fatigue

Contact your doctor if you experience serious or persistent symptoms.

Monitor your calcium levels regularly as advised by your healthcare provider.
Avoid taking any other vitamin D supplements unless directed by your doctor.
Inform your doctor about any other medications you are taking to avoid interactions.
Limit alcohol consumption while using this medication.
Seek medical advice if you experience symptoms like extreme thirst, frequent urination, or confusion.

Always consult your doctor for personalized advice and recommendations.

Frequently Asked Questions

What does Alfacalcidol do to the body?

Alfacalcidol helps regulate calcium levels in the body, promoting healthy bone formation and maintenance.

How long does it take for Alfacalcidol to start working?

The effects of Alfacalcidol may be noticed within a few days, but it may take longer for full benefits to be observed.

Is Alfacalcidol safe for long-term use?

Alfacalcidol can be safe for long-term use under medical supervision, especially for managing chronic conditions.

Can Alfacalcidol interact with other medications?

Yes, Alfacalcidol can interact with certain medications. Always inform your doctor about all medicines you are taking.

What should I do if I miss a dose of Alfacalcidol?

If you miss a dose, take it as soon as you remember unless it’s almost time for your next dose. Do not double up doses.