Mercaptopurine

Mercaptopurine is a medication used primarily in the treatment of certain types of cancer. It belongs to a class of drugs known as antimetabolites.

This medication is often prescribed to manage conditions where the control of abnormal cell growth is needed.

Information about Mercaptopurine

Mercaptopurine Uses

Mercaptopurine is typically used in the management of several health conditions related to abnormal cell growth.

  • Acute lymphoblastic leukemia (ALL)
  • Chronic myeloid leukemia (CML)
  • Inflammatory bowel diseases, such as Crohn’s disease and ulcerative colitis

How Mercaptopurine Works

Mercaptopurine works by interfering with the growth and spread of cancer cells in the body. It mimics the natural substances in the cells, disrupting their normal function.

This action helps to slow down or stop the growth of cancer cells, providing a therapeutic effect in conditions like leukemia.

Common side effects of Mercaptopurine

Not everyone experiences side effects with Mercaptopurine, and many side effects are mild and temporary.

  • Nausea
  • Vomiting
  • Loss of appetite
  • Diarrhea
  • Fatigue
  • Rash
  • Low blood cell counts

If you experience serious or persistent side effects, it is important to contact your doctor.

CONTENT DETAILS

Written By
Douglas C. Goldberg, MD
Reviewed By
Philip Schein, MD
Last updated
28 Nov 2025 | 03:00 PM (UTC)

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Expert advice for Mercaptopurine

  • Regularly monitor your blood cell counts as advised by your doctor.
  • Avoid consuming alcohol while taking this medication.
  • Inform your doctor of any other medications or supplements you are taking to avoid interactions.
  • Do not use Mercaptopurine if you have certain symptoms like severe liver problems without consulting your doctor.
  • Stay in touch with your healthcare provider to manage any side effects effectively.

Always consult your doctor for personalized medical advice.

Frequently Asked Questions

What is Mercaptopurine used for?

Mercaptopurine is used to treat certain types of cancer, such as leukemia, and some inflammatory bowel diseases.

How does Mercaptopurine work?

It works by interfering with the growth of cancer cells, helping to slow or stop their spread.

Are there any common side effects of Mercaptopurine?

Yes, common side effects include nausea, vomiting, loss of appetite, and fatigue.

Can I drink alcohol while taking Mercaptopurine?

It is generally advised to avoid alcohol while taking Mercaptopurine.

Should I monitor any specific symptoms while on Mercaptopurine?

Yes, regular monitoring of blood cell counts is important, and report any unusual symptoms to your doctor.

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