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Betahistine is indicated to treat the illness and Menier’s syndrome, which are characterized by three main symptoms: dizziness, which is sometimes accompanied by nausea and vomiting; hearing loss (torture); noise in the ears. And also the drug is used for the symptomatic medical care of vestibular dizziness of various origins. Betahistine – a remedy for the medical care of vestibular problems. In fact, Betahistine is an inhibitor of the H3 receptors in the nuclei of the vestibular apparatus. This agent has a pronounced effect on the central nervous system, with the stabilization of the neuronal transmission in the neurons of the vestibular nucleus.
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Common use
Betahistine (Betahistine dihydrochloride) is primarily used to treat Ménière’s disease, a disorder of the inner ear that causes episodes of vertigo (a spinning sensation), tinnitus (ringing in the ears), hearing loss, and a feeling of fullness or pressure in the ear. Betahistine acts as a histamine analog, improving blood microcirculation in the inner ear, which helps to reduce the pressure of excess fluid and restore balance.
Dosage and direction
The standard adult dose is 16 mg taken two to three times daily, preferably with meals to reduce gastrointestinal side effects. Tablets should be swallowed whole with water. The dosage may be adjusted based on the severity of symptoms and the patient's response to treatment. Consistency is important for maximum effectiveness; it may take a few weeks to notice significant improvement.
Precautions
Before using Betahistine, inform your doctor if you have: Asthma (due to potential bronchospasm), Peptic ulcer or a history of stomach ulcers (as betahistine may increase gastric acid secretion), Hypotension (low blood pressure), Pregnancy or breastfeeding — safety is not fully established. Caution is also advised in elderly patients or those with impaired liver/kidney function.
Contraindications
Known hypersensitivity to betahistine or any of the tablet’s components. Pheochromocytoma (a rare adrenal gland tumor), as betahistine may induce a hypertensive crisis. It should not be used without medical supervision in children or adolescents due to lack of data on safety and efficacy.
Possible side effect
Common side effects may include: Mild gastrointestinal disturbances: nausea, dyspepsia, bloating. Headache or dizziness during the initial phase of treatment. Allergic reactions, such as rash, itching, or hives (rare). Most side effects are mild and transient, and improve as the body adjusts to the medication.
Drug interaction
Betahistine may interact with antihistamines (e.g., cetirizine, loratadine), potentially reducing the effectiveness of either drug. Monoamine oxidase inhibitors (MAOIs), including some antidepressants, may increase betahistine levels and effects — caution is advised. No significant interaction with alcohol or common antibiotics, but it's best to consult a physician before combining medications.
Missed dose
If a dose is missed, take it as soon as you remember. If it's almost time for your next scheduled dose, skip the missed dose — do not take a double dose to make up for it.
Overdose
Although rare, symptoms of overdose may include: Nausea, vomiting, stomach pain, drowsiness, or seizures in extreme cases. In the event of suspected overdose, seek immediate medical assistance or contact a poison control center.
Storage
Store the medication at room temperature (15–25°C / 59–77°F). Keep away from heat, moisture, and direct sunlight. Store in the original blister packaging, out of reach of children and pets. Do not use after the expiration date printed on the box.
Disclaimer
We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.