Bupropion

Common use

Bupropion is an atypical antidepressant used to treat major depressive disorder (MDD) and seasonal affective disorder (SAD). It is also prescribed as a smoking cessation aid under the brand name Zyban. Bupropion works by affecting the levels of dopamine and norepinephrine in the brain, helping to improve mood, energy, and focus.

Dosage and direction

Bupropion is typically taken once or twice daily depending on the formulation (immediate-release, sustained-release, or extended-release). It should be swallowed whole, not crushed or chewed, to avoid increased risk of side effects. Always take the medication exactly as prescribed by your doctor and avoid taking doses too close together to reduce the risk of seizures.

Precautions

Contraindications

Possible side effect

Common side effects include dry mouth, insomnia, headache, sweating, nausea, and dizziness. Serious side effects may include seizures, high blood pressure, mood changes, or allergic reactions. Seek immediate help if you experience chest pain, hallucinations, or difficulty breathing.

Drug interaction

Bupropion may interact with MAOIs, antipsychotics, other antidepressants, and drugs that lower the seizure threshold. It may also affect blood levels of certain medications like digoxin. Inform your doctor about all prescription, nonprescription, and herbal products you are taking.

Missed dose

Overdose

Storage

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