Samsca

Common use

Samsca is primarily used to correct clinically significant hyponatremia (low sodium levels) in patients with normal blood volume or fluid overload, particularly when associated with heart failure or SIADH.

Dosage and direction

Samsca is usually prescribed starting at 15 mg once daily, with adjustments made based on the patient’s response and sodium levels. It should be taken orally, with or without food, and under hospital supervision during initiation to monitor sodium correction.

Precautions

Contraindications

Possible side effect

Common side effects include thirst, dry mouth, frequent urination, constipation, and weakness. More serious effects may include rapid sodium correction (leading to neurologic symptoms), liver injury, or dehydration.

Drug interaction

Tolvaptan may interact with CYP3A inhibitors or inducers, increasing or decreasing drug levels. Use caution with digoxin and diuretics, as additive effects on electrolytes and fluid balance may occur.

Missed dose

Overdose

Storage

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.