Tamoxifen

Common use

Tamoxifen is a selective estrogen receptor modulator (SERM) used primarily to treat and prevent breast cancer. It works by blocking estrogen receptors in breast tissue, slowing or stopping the growth of hormone-receptor-positive tumors. Tamoxifen is also prescribed to reduce the risk of breast cancer in high-risk patients. It is effective in both premenopausal and postmenopausal women.

Dosage and direction

Tamoxifen is usually taken once daily, with or without food, at a dose of 20 mg, though dosages may vary depending on the condition being treated. It should be taken at the same time each day for consistency. Swallow the tablet whole with water. Treatment duration can range from 5 to 10 years based on the individual case and doctor’s recommendation.

Precautions

Contraindications

Possible side effect

Common side effects include hot flashes, vaginal discharge, irregular menstruation, and fatigue. Less common but serious effects include blood clots, stroke, and endometrial cancer. Some patients may experience mood changes or visual disturbances. Seek medical attention if you notice leg swelling, chest pain, or unusual bleeding.

Drug interaction

Tamoxifen may interact with certain antidepressants (such as fluoxetine and paroxetine), which can reduce its effectiveness. It may also interact with blood thinners like warfarin, increasing bleeding risk. Inform your doctor about all medications, supplements, and herbal products you are taking. Dose adjustments or alternative therapies may be required.

Missed dose

Overdose

Storage

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.