Hydrochlorothiazide

Common use

Hydrochlorothiazide is a thiazide diuretic used to treat high blood pressure and fluid retention (edema) caused by various medical conditions, including heart failure, liver disease, and kidney disorders. It helps the body eliminate excess salt and water through urine. Lowering blood pressure reduces the risk of stroke, heart attack, and kidney problems. It is often used alone or in combination with other antihypertensive drugs.

Dosage and direction

The medication is usually taken once daily in the morning, with or without food. Dosage varies depending on the condition being treated and individual response, typically starting at 12.5–25 mg per day. Take the tablet with a full glass of water. Avoid taking it late in the day to prevent nighttime urination.

Precautions

Contraindications

Possible side effect

Common side effects include increased urination, dizziness, headache, and muscle cramps. It may also cause low potassium, low sodium, high blood sugar, or elevated uric acid levels. Rare but serious reactions include severe dehydration, pancreatitis, or allergic responses. Seek medical attention if you experience irregular heartbeat, severe fatigue, or difficulty breathing.

Drug interaction

Hydrochlorothiazide may interact with other blood pressure medications, NSAIDs, lithium, corticosteroids, and diabetic drugs. Combining it with alcohol or barbiturates may enhance dizziness or fainting. Use with digoxin requires caution due to electrolyte imbalances. Always inform your doctor about all medications and supplements you are taking.

Missed dose

Overdose

Storage

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.