Nitrofurantoin

Common use

Nitrofurantoin is an antibiotic used primarily to treat and prevent urinary tract infections (UTIs). It works by interfering with bacterial enzymes, damaging the bacteria's DNA and killing them. The drug is effective against most common urinary pathogens, including E. coli. It is not suitable for infections outside the urinary tract.

Dosage and direction

Nitrofurantoin is typically taken orally with food to improve absorption and reduce stomach upset. The dosage depends on the type and severity of the infection, as well as the patient’s age and kidney function. It is important to complete the full course even if symptoms improve early. Always follow your doctor's instructions carefully.

Precautions

Contraindications

Possible side effect

Common side effects include nausea, headache, loss of appetite, and flatulence. Some patients may experience dizziness or drowsiness. Serious side effects such as lung inflammation, liver damage, or nerve pain are rare but require immediate attention. Allergic reactions and skin rashes may also occur.

Drug interaction

Nitrofurantoin may interact with antacids containing magnesium trisilicate, which can reduce its absorption. It should also be used cautiously with drugs that affect kidney function. Concurrent use with probenecid or sulfinpyrazone may increase nitrofurantoin levels, raising the risk of toxicity. Always tell your healthcare provider about all medications you are taking.

Missed dose

Overdose

Storage

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. The specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.