Alternatives to Nitrates When Treating with Viagra and Cialis

April 17, 2019/in Generic Viagra /by Md. Philip Schein

Ischemic heart disease (IHD) is an acute or chronic myocardial damage resulting from a decrease or cessation of the supply of arterial blood to the heart muscle. Forms of IHD include angina pectoris (stable and unstable), myocardial infarction, heart failure, etc.

Unfortunately, coronary artery disease and erectile dysfunction (ED) in men often coexist. Inhibitors of phosphodiesterase type 5, such as Viagra and Cialis, have revolutionized the treatment of ED. However, they cannot be used together with nitrates, which are often prescribed to combat angina pain. Therefore, some patients have to look for substitutes.

Nitrate Drugs – What Are They?

Nitrates are drugs that are designed to eliminate the anginal pain that occurs with angina and myocardial infarction. According to practitioners, they occupy one of the leading places in cardiology practice.

Organic nitrates are divided into 2 groups by the duration of action:

short-acting (stop attacks of anginal pain with angina or heart attack);
long-acting (used for the prevention of angina attacks).

After entering the body from the nitrate molecule, the NO group is split off, which activates guanylate cyclase and thereby causes an increase in the level of cyclic guanosine monophosphate. The accumulation of this substance leads to the relaxation of smooth muscles of the walls of the coronary vessels, arteries and veins.

Nitrate class includes nitroglycerin, isosorbide dinitrate and isosorbide-5-mononitrate. They are available in various forms, including capsules, sublingual tablets, sprays, aerosols, mucoadhesive buccal patches, etc.

According to Drugs.com, their brand names include:

Minitran, Nitrek, Nitro-Bid, Nitro-Dur, Nitrolingual, NitroMist, NitroTab, Nitro-Time, Rectiv, Tridil (nitroglycerin);
Isordil Tembids, Isordil Titradose, Isosorbide Dinitrate CorePharma, Apo-ISDN, Isocord, Isocin (isosorbide dinitrate);
Imdur, Ismo, Isosorbide Mononitrate Actavis, Monoket, Apo-ISMN, PMS-Isosorbide, Monocord, Monocordil (isosorbide-mononitrate).

Options for Replacing Nitrates in the Treatment of ED

The use of nitrates in combination with PDE5 inhibitors is strictly contraindicated. This can lead to a rapid decrease in blood pressure (even fatal outcomes are known). Also, such a pernicious combination can lead to myocardial ischemia (due to a decrease in blood flow in stenotic coronary arteries).

So if you need to use Viagra or Cialis, you have two options. The first option is to ensure a sufficiently long gap between the use of nitrates and anti-ED drugs. Viagra is effective for 4-6 hours, but its particles may remain in the body longer. As Russian scientist V. Lupanov (2011) rightly points out, phosphodiesterase inhibitors used to treat erectile dysfunction from sildenafil, vardenafil, and tadalafil groups potentiate the hypotensive effect of nitrates, therefore, the use of nitrates should be avoided for 24-48 hours after using phosphodiesterase inhibitors. According to WebMD, in some cases, a man can stop taking nitrates to ensure the safe use of the drug to treat sexual impotence. However, patients who participated in the cited study took other heart remedies.

The second option involves the replacement of nitrate drugs used in antianginal therapy. As indicated in the study of American scientists Dioma U Udeoji and Ernst R Schwarz (Los Angeles, 2014), beta-blockers and calcium channel antagonists are usually considered the main means in antianginal therapy, but not all patients are well tolerated by these drugs. Moreover, some beta-blockers were associated with an increase in the incidence of male impotence. Scientists have tested the use of ranazoline (brand names Ranexa, Caroza, Cartinex, Rancad) as a replacement for nitrates. This medication causes a minimal reduction in blood pressure and a slight decrease in heart rate. All patients reported improved sexual function with ED drugs and control of symptoms of angina with ranazoline. Despite the fact that Ranexa may cause side effects (dizziness, headache, stomach problems), there are no contraindications for its joint administration with PDE5 inhibitors. However, this issue requires more detailed examination.

Other Considerations

If you are taking nitrates and decide to buy Viagra (Cialis), you should consult with your doctor about how to get out of this extraordinary situation. Viagra is not a vitamin supplement, and it is cannot be self-prescribed in case of heart diseases that lead to the consumption of nitrates, since this practice may be unsafe.

Viagra Abuse and Recreational Use: Risks & Dangers

March 28, 2019/in Generic Viagra /by Md. Philip Schein

Viagra is an anti-ED medication which should be used only if a patient suffers from erectile dysfunction. Its dosages should not exceed norms indicated in the instructions. However, these two simple rules are often violated by ED sufferers and even healthy males. Both Viagra abuse and recreational use may be associated with some health risks.

Viagra Abuse: Don’t Put Your Health in Peril

Back in 1998, after Viagra appeared on the market (making a revolutionary splash), a boatload of healthcare professionals were worried about the blatant cases of abuse of this “spellful” drug. Patients used it in quantities that were bigger than sanctioned ones. Situation has not changed since the date of the reports.

The key risk of using increased dosages of Viagra is overdose, and, subsequently, the possibility of more severe side effects occurrence. It’s known that the most frequent sides of the drug include:

headaches* (probably the most widespread unwished effect);
feeling dizzy;
blurred vision, cyanopsy (impaired color perception when a patient begins to see everything in blue);
hot face flashes;
nasal congestion;
nausea, dyspepsia, other gastrointestinal problems.

Contrary to popular belief, prolonged erection and priapism are not frequent occurrences when treating with Viagra. The medicine can also cause other unhealthinesses (like memory problems, ringing in the ears and hearing loss), however, they are typically rare.

However, in case of overdosage the abovementioned undesirable effects may be much severer. For instance, a man may experience loss of vision, a significant change in color perception, a sharp drop in blood pressure, a really bad headache, dangerous cardiovascular disorders, and priapism. There have been more sad occasions associated with the drug’s overdose, for example, amputation of the male organ, hospitalization with painful priapism, and even death due to the cardiac issues provoked by sildanafil and excessive sexual activity.

The most optimal dose of the medication is 50mg. Males with some pronounced health problems may take lowered dosage – 25mg, while patients with severe degree of ED or low responsiveness to sildenafil may switch to 100mg.

Many older drug users may unconsciously mix heart medications with impotence pills, which can lead to other health complications. When using very high dosages of the drug, the consequences can be unpredictable.

It is important: never combine sildenafil with nitrates (glyceryl trinitrate, isosorbide dinitrate, and isosorbide mononitrate.).

Some examples include: Minitran patch by Medicis Dermatologics, Nitrek by Bertek, Nitro-Bid by Savage, Isordil Tembids by Wyeth (in the United States); Apo-Nitroglycerin by Apotex, Nitro-Dur by Merck, Apo-ISDN by Apotex (in Canada).

What is Recreational Use of Drugs?

Recreational use (“recreation” means “rest”, “recuperation”) is the use of drugs that are not related to medical indications, for pleasure or other purposes. Opiates and cocaine, other psychostimulants, psychedelics and hallucinogens are most often used for recreational purposes. However, other drugs, especially Viagra, are no exception. Using recreational meds means that you are at risk. It can be unsafe and at some point, such usage can simply get out of control.

Viagra Recreational Use

What does Viagra do, according to the crowd’s opinion? Some people believe that it improves libido (sexual attraction), but this is not the case. This issue needs serious consideration, given the increasing wave of Viagra users. Viagra as a drug to improve penile erection is a very popular product, which occupies a permanent place in the lives of some party lovers.

Viagra may be combined with narcotics when used recreationally. Dennis G. Fisher, Robert Malow et al. (2006) detected consistent associations between the recreational use of sildenafil-based meds and amphetamines immediately before or during sexual intercourse. Moreover, according to the WebMD, abuse of the drug among males who have sexual contacts with other males may elevate the risk of sexually transmitted diseases and HIV. Of course, the Pfizer’s tablet itself doesn’t cause dangerous infections, however, researchers says that prolongation of penile erection time, better blood flow to the penis, and subsequent active sex may elevate the risk of catching these infections from a partner. Having pumped up with drugs and Viagra, a person gets wild sexual energy like a raging bull. He goes to bed to have filthy hot sex, discarding caution.

Moreover, males with recently diagnosed the human immunodeficiency virus more often use Viagra than non-infected fellows.

Conclusions

Be judicious and circumspect, when using Viagra to treat erectile dysfunction. Do not think that more is better. In fact, excessive doses mean more hazardous influence on the body. It is also not advised to use this pharmaceutical product for recreational purposes (“for fun”). Good health is the most precious of all possessions, so take care of it.

Female Viagra Effect: How Does It Work?

March 21, 2019/in Generic Viagra /by Md. Philip Schein

Female Viagra is definitely a less popular drug than the male one however, this doesn’t mean that it is non-widespread. According to special analysis, it is searched in Google about 250 thousand times monthly (ordinary “blue pill” features 1.5 mln queries). It is well-known how usual Viagra acts in the male system, but there is no enough data about its female variant. Hence, many women are interested in how this drug works in the female body.

What is Female Viagra?

Like the drug for gentlemen, the option for ladies is also based on sildenafil citrate, a pharmaceutical component belonging to PDE5 inhibitors category. There are other meanings of “female Viagra” term, but we’ll talk about them later.

This medicament is available under several brand names, including Female Pink Viagra, Lovegra, Womenra, and Femalegra. They are sold in classic dosages: 50mg and 100mg.

The drug helps to remove problems with low libido and return balance to the sex life of a woman.

Principle of Action – What Do Researchers Think?

Let’s get a close look at some works which describe the action of sildenafil in the female organism.

It is known that sildenafil-based Viagra revolutionized the treatment of ED in males in the 1990s. The medication acts by inhibiting PDE5 enzyme (phosphodiesterase type 5), which leads to cyclic guanosine monophosphate (cGMP) levels elevation in penile corpora cavernosa resulting in muscle relaxation and better blood flow into the male organ. It has been found that some isoforms of PDE enzyme are present in the clitoris, vagina, and labia minora. Therefore, the drug’s mechanism of action in males may be extrapolated to females. Here’s information taken from different scientific studies:

Cavalcanti A.L., Bagnoli V.R. et al. (University of São Paulo, 2008). The researchers reported that sildenafil may enhance blood circulation in the clitoris and improve GRISS (the Golombok Rust Inventory of Sexual Satisfaction – a questionnaire for the assessment of sexual dysfunction) scores in menopausal females suffering from orgasmic disorders.
Berman J.R., Berman L.A. et al. (the University of California, Los Angeles, 2003). They evaluated efficiency and safety of administering sildenafil by patients with female sexual arousal disorder, concluding that the substance was good-tolerated and efficient in the group of women without concomitant hypoactive sexual desire disorder (HSDD, it’s when a woman loses interest in sex) or contributory emotional/relationship issues, that is problems with a partner.
Basson R., McInnes R. and others (Vancouver Hospital and Health Sciences Center, 2002). They wrote that specific groups of women with FSAD could benefit from sildenafil therapy.

Generally speaking, if a problem is physiological (not psychological), the pink-colored pill can be definitely helpful.

The medication can be advantageous in coping with sexual arousal disorder and female sexual dysfunction (FSD). By the way, FSD, as stated by Brazilian scientists Kyan J. Allahdadi and Rita C.A. Tostes (2010), is quite a prevalent problem, which affects approximately 40% (!) of women and implies the use of few treatment options.

Female Pink Viagra Benefits

Many folks are mistaken, considering that Viagra is only a male pill. Over time, women need a drug that enhances pleasant sensations during sex. Manufacturers of the product claim that the product has the following favorable effects:

elevates libido, impaired by different factors;
boosts sexual response;
potentiates natural vaginal lubrication;
helps to cope with anorgasmia or poor orgasms, enhances feelings during the peak of sexual pleasure.

The effect of the preparation lasts for about 4-6 hours (like in men), but it can stay in the system (providing the necessary effect) up to 12 hours. The tablet’s onset of effect is observed in 30-60 minutes after administration. It has high safety profile when used by females, as it has been repeatedly tested in this category of patients, in particular, in spite of treatment with Revatio (it is also a sildenafil-based product administered for treating pulmonary arterial hypertension).

Please read Female Pink Viagra description here.

Flibanserin (Addyi) and Other Options for Combating Low Libido in Women

Flibanserin is a controlled RX medication, which has been developed for females who have apathy in sexual life. Its mechanism is different to that of Female Pink Viagra, it acts like antidepressant. The medicine is available in a limited number of pharmacies and has quite a big price. It is not advisable to use Flibanserin without a prescription.

Some products are believed to be natural libido enhancers in women, so they may be also referred to as “female Viagra”. Well, correction of the diet is important key of healthy life, including sexual one, but if a problem is severe, it is arduous to cope with it using only natural methods.

You can read more about the male libido and Viagra.

What to Choose?

If you wanna deal with the problem quickly, you can opt for Female Pink Viagra, which may be used generally by all gals, not only by postmenopausal women. It is usually available without a prescription (as an OTC medication).

Can You Improve Your Libido Using Viagra?

August 3, 2018/in Generic Viagra /by Douglas C. Goldberg, MD

The problem of low libido is considered more common for women than for men. Even those male persons who experience erectile dysfunction usually do not complain about lack of sexual desire. However, interest in sex can diminish in some men who are getting older. A very small number of male persons have never felt a sex drive in their entire lives.

What Is Libido?

Libido is a sexual desire which is one of the main functions of the body. Poor libido is a real problem for many people. Libido quality can be affected by a wide range of factors including stress, season, lifestyle, sedentary job and depression. This term began to be extensively used after Sigmund Freud’s publications devoted to psychoanalysis.

Libido is controlled both by the production of testosterone, formed under the influence of the pituitary gland, and the nervous system. Such functions of the body as ejaculation, erection and other sexual abilities are controlled by the brain. Hence, very often the cause of a decreased or increased libido lies precisely in the activity of the nervous system.

Excessively strict upbringing in childhood can instill aversion to sexual actions and, as a consequence, reduce the level of libido in people of both sexes. A huge role in the formation of libido is played by hormones. Due to hormonal disorders in men or women, there may be a complete reluctance to have sex.

In the 21st century there appeared a great number of clinics and firms claiming they specialize in treating poor libido in male persons. These clinics emerge and disappear. They often charge rather high fee for the medical services they provide. Among the treatment options are testosterone courses and taking aphrodisiac, for example ginseng-based products.

Several years ago, we could see billboards containing information about nasal sprays allegedly curing low libido. Fortunately, these adverts can hardly be encountered today as such claims are rather doubtful and should be perceived with caution.

How Frequent Are Lack of Libido Cases in Men?

There are fewer men experiencing lack of libido than those suffering from erectile dysfunction. These conditions should be clearly distinguished.

As medical practice suggests, the ratio between low libido male persons and those suffering from erectile dysfunction is 1:25. The majority of men experiencing poor libido are able to achieve erection, however they do not feel a sexual desire.

What Are the Most Typical Factors Causing Lack of Libido?

Similar to women, men experience lack of sexual desire due to either psychological or physical factors.

The physical (organic) causes are the following:

Alcoholism – rather common causative factor.
Drug abuse (for example cocaine).
Obesity – common; losing weight will help.
Anaemia – unusual, if the man has not been bleeding because of any reason.
Hyperprolactinaemia – a rare condition under which the pituitary gland “manufactures” excessive amount of prolactin.
Prescribed drugs – in particular, Proscar (Finasteride*), a medication used for treating prostate problems, and meds which affect the brain.
Low level of testosterone – in spite of the public opinion, this is not common, except for cases where testicles have been affected by some illness or injury.
Severe health disorders, for example, diabetes.
Injury of head.
The thyroid gland in an underactive condition.

The psychological causes include depression (very common), overwork and frequent / acute stress, latent homosexuality, anxiety from childhood, relationship problems with a partner.

* For more information about Proscar (Finasteride), please visit this page: https://awcanadianpharmacy.com/item/proscar.html

Low Libido Treatment

Among the ways of a decreased libido treatment there are both medicament-based and psychological ones. In particular, if the hormonal balance is not broken, and the patient does not suffer from diseases of the genitourinary system, he should take care of interaction with the partner, changing the interior in the bedroom, finding new poses. An important factor in the normal sexual life and regulation of libido is a foreplay.

The romantic component of the relationship between partners is crucially important. If the patient experiences constant stress during the day, he needs to minimize conflict situations and eliminate nervousness. Communication with a partner and a joint visit to the psychotherapist can help to find the true causes of loss of sexual desire.

In case of diagnosing psychological disorders hormonal medications can be prescribed only by a doctor, they should not be taken without recommendation. If the hormonal disorder is due to the presence of another disease, the first thing to be done is eliminating the cause.

What Steps Should You Take in Case of Low Libido?

To begin with, make an appointment with your general healthcare expert, who will do a physical check-up and recommend you to submit to the blood test he considers necessary, for example, thyroid tests or blood count. If your case is complicated, your doctor can issue a referral to other specialists.

The causes of low libido described above typically respond adequately to therapy. Doctors state that the most difficult to handle are causes associated with marital problems and anxiety about sex.

Is it possible to treat lack of sexual desire with drugs? Currently the pharmaceutical market cannot offer any drugs specifically developed for increasing libido in men except for cases caused by low testosterone when prescribing this hormone will be appropriate. Such anti-ED drugs as Viagra, Cialis, and Levitra do not influence sexual drive, as they only have effect on erection.

Connection Between the Body and Mind

The brain is considered an essential sex organ. Thus, feeling good means getting sexually aroused easily and vice versa. If a man is suddenly unable to achieve erection there must be a psychological reason behind it: redundancy, divorce, or bereavement can lead to loss of confidence or anxiety.

In general, such psychological conditions as low self-esteem, boredom, incompatibility, fatigue and depression make sex less alluring. Women are especially vulnerable to a combination of physical and lifestyle changes, for example, childbirth. Therefore, it is sensible to choose a complex approach to treating sexuality problems. It implies doing exercises aimed at improving stamina & body image, enhancing ability to deal with financial and work stress effectively, as well as special pelvic exercises for female persons to raise their awareness of groups of muscles engaged in sexual pleasure and libido boosting.

Can Viagra Boost Libido?

If you ask a question whether Viagra is aphrodisiac which can increase libido, the answer is “No”. This remedy is a prescription medication developed for handling impotence or erectile dysfunction in male persons.

Generic Viagra neither enhances sexual drive nor increases sexual pleasure. Its action is improving sexual performance by stimulating blood flow to the penile area. Although this drug improves sexual performance it does not cause sexual desire. On the contrary, aphrodisiacs make a person feel sexual drive.

In general terms, substances belonging to the category of aphrodisiacs contribute to enhancing sexual drive. In addition, they encourage responsiveness between the sexual partners and help to increase an orgasm sensation. Many ancient cultures used such plants as datura, henbane, and belladonna for centuries to enhance sexual desire (do not use these herbs on your own because they are toxic!).

Nowadays, many people use such herbs and foods as yohimbe (or yohimbine supplement, such as Yohimbe-1200), ginseng, oysters, mandrake plants, Vitamin E, and chocolate as aphrodisiacs. There are other substances which are considered to have aphrodisiac properties. Among them are L-Dopa, Bupropion, arginine, and citrulline.

The Dangers of Counterfeited (Fake) Viagra

July 25, 2018/in Canada Drugs, Generic Viagra /by Douglas C. Goldberg, MD

Online pharmacies are a very convenient way to buy the necessary medicines, especially those for treating ED. After all, men value their privacy very much and do not want anyone to know about their problems. Unfortunately, the online pharmaceutical market offers many counterfeits that are associated with some health risks.

Counterfeited Drugs in Online Pharmaceutical Market

According to estimates of experts from international organizations, counterfeits account for 40% of the world pharmaceutical market. The WHO believes that on the Internet, part of counterfeit medicines can be up to 50 per cent. Experts say that counterfeiting of medicines has turned into the largest international underground business comparable in scale to drug trafficking, with the only significant difference that no one is insured against the threat of buying counterfeit drug, regardless of social status and income level.

In most cases, counterfeit medicines are not equivalent to the original drugs or generics in terms of quality, effectiveness, or side effects. Examples of counterfeits include widely used drugs, e.g. paracetamol, controlled substances such as human growth hormone, which is often illegally used in sports, and other types of drugs such as Viagra and Cialis. Viagra is counterfeited quite often, because it is a very popular medication among men suffering from erectile dysfunction. At the same time counterfeiters very skillfully forge the original medication. They give the tablet the same shape as original Viagra, put the same markings and offer medicines in the same package.

*Check our non-counterfeited Canadian Viagra: https://mycanadianhealthcaremall.com/product/viagra/

Pfizer’s Experiment

Several years ago, Pfizer Inc. (the developer of genuine Viagra) conducted its own investigation. Experts of this company bought Viagra from various sites, including suspicious ones, which claimed that they were selling the original Pfizer medicine.

Here is what they found in the counterfeited Viagra and other drugs:

blue printer ink (counterfeiters have used it to give the tablets a blue color);
amphetamines;
Metronidazole*, an antibiotic that can cause gastrointestinal upset in large dosages;
increased dosages of the active substance, which increases the risk of side effects and can cause harm to the body;
binding agents, for example, drywall, which prevent the absorption of the tablet in the digestive tract;
toxic substances, for example, road paint and rat poison, which can cause poisoning of the body and even lead to death;
a completely different medication that has a different effect on the body and potential side effects.

*For more information about Flagyl ER (Metronidazole), please visit this page: Coming Soon!

What to Look Out For

Dangers of Counterfeited Viagra Use

There are several types of counterfeit medicines on the pharmaceutical market:

“Empty” drugs. They are usually not dangerous, but they do not give the desired effect. Counterfeiters add empty fillers to them and that’s it. Although in some cases they can work by analogy with placebo.
Medications that mimic treatment. They contain some active ingredients (for example, extracts of some plants), but these ingredients are cheaper and much less effective. They can have a curative effect, but they do not work as well as sildenafil (the basic component of Viagra).
Medicines with a low dose of active agent. The minimum dosage of Viagra is 25 mg, it is also available in 50 mg and 100 mg dosages. Some counterfeiters may decrease the dosage of the active substance. As a result, the medication may not work or exert a weaker effect.
Medications with increased dosage. It is not known why some scammers add more active substance than necessary. However, such counterfeits exist on the pharmaceutical market. They can have a stronger effect but their use is associated with a much higher risk of side effects.
Meds containing wrong ingredients. This is a dangerous kind of fakes when manufacturers add to the tablets cheap antibiotics or something else instead of sildenafil and other active substances. Such “medicines” can be dangerous to health because a person may have an allergy to the ingredients actually contained in a counterfeit medication. In addition, such products can cause unpredictable side effects and react unpredictably with other medicines.

Experts believe that all falsifications are potentially dangerous for health, since they are not subject to quality control required for legal medicines.

However, the most dangerous thing is when counterfeit medicines contain harmful chemical ingredients (examples of such ingredients have been described above). In this case, the patient will not only get the desired effect, but will also do harm to their health. So be very careful when buying Viagra on the Internet.

How to Avoid Counterfeits When Buying Viagra?

When you buy medicines on the Internet, evaluate the appearance of the website. Also, check if the site has an SSL security certificate and if there is a form for contacting the support service. In addition, it would not be superfluous to read reviews of users who have already bought medicines in this online pharmacy. If you see a kind of original medicine at a low price, it is most likely a fake. Legal generics do not claim that they are originals, they can have a different form.

By adhering to these simple rules, you can avoid fake Viagra on the Internet.

Another tip: you can get free samples of Viagra (Canadian Health Care Mall provides such an opportunity) and check their quality. If you are satisfied, you can order in this pharmacy in the future. My Canadian Pharmacy guarantees high quality of anti-ED medications.

Viagra and Antidepressants – Associated Erection Problems

May 1, 2018/in Generic Viagra /by Douglas C. Goldberg, MD

In about 10-20% of cases, the cause of the development of erectile dysfunction are psychological factors. One of the psychological disorders that is often associated with ED is the ordinary depression. To cope with this disorder, many men start taking antidepressants. These drugs are powerful helpers (especially when combined with the help of a psychotherapist), however, some of them can cause ED or aggravate this disease if it already exists.

Depression and the Use of Antidepressants

Depression is a real scourge of our time. About 350 million people around the world suffer from this illness. Contrary to alarming numbers, many of us tend to underestimate the dangers of a depressed state.

Depression is a serious psychological disorder, which often affects not only the patient himself, but also his loved ones.

You may have depression if, for a long time (two weeks or more), you observe the following symptoms:

reduced mood throughout the day;
a decrease in the sense of satisfaction from life and interest in it;
decrease in appetite;
insomnia combined with drowsiness;
agitated behavior (excessive mobility or slowness or a combination thereof);
a sharp decrease in energy levels;
a pessimistic view of what is happening;
a sense of inferiority and guilt;
the inability to focus and concentrate;
periodical thoughts about death / suicide.

The core of any depression is unmotivated deep melancholy. This inhibits all mental processes, which are experienced quite painfully. There are complaints of memory disorders, internal emptiness, chest pain, and even joint pain.

Recently, Canadian scientists discovered that a long depression can lead to changes in the brain, similar to Alzheimer’s or Parkinson’s diseases. Therefore, you must not leave this disorder without treatment.

The main directions of depression therapy are pharmacotherapy, psychotherapy, and social therapy. Pharmacotherapy is performed with the help of antidepressants. These medications are prescription (RX) products and are used for depression of moderate to severe grade. They include the following groups of meds:

Selective serotonin reuptake inhibitors (or SSRIs, SRIs is a broader term including non-selective meds). Examples: Celexa, Lexapro*, and Prozac.
Monoamine oxidase inhibitors. Examples: Isocarboxazid (brand name Marplan) and Phenelzine (brand name Nardil).
Tricyclic antidepressants. Examples: Desipramine (Norpramin) and Zonalon (Doxepin).
Atypical antidepressants. The class of these meds includes Bupropion (Wellbutrin) and Mirtazapine (Remeron).
Selective serotonin & norepinephrine reuptake suppressors. Among them are Desvenlafaxine (brand name Pristiq) & Duloxetine (brand name Cymbalta**).

* For more information about Lexapro, please visit this page: link coming soon

* For more information about Cymbalta, please visit this page: link coming soon

Antidepressant-Associated Erection Disorders

Scientists report that erectile problems occur in about 30 to 70 percent of men who use serotonin reuptake inhibitors, which are often prescribed antidepressants, for example, Prozac and Celexa. Side effects may include impaired sex drive (libido), deteriorated excitation processes, and orgasm problems. These effects can be so severe that most people who use these antidepressants begin to cancel their administration too early, which may lead to recurrence of depressive state (that is, depression comes back). However, Viagra can become an Aladdin’s lamp in such cases.

It should be noted that antidepressants can cause sexual dysfunction not only in male persons but also in women. Fortunately, Canadian Viagra can also help in case of deterioration of the female libido (we will discuss this issue in more detail below).

Viagra as a Remedy for Treating Drug-Induced Sexual Problems

Back in the early 2000s, scientists at the University of New Mexico conducted a study according to which more than half of men with drug-induced erectile problems experienced significant improvement as a result of the administration of Viagra. Also, researchers reported that erectile function, orgasm, and satisfaction with sexual life improved significantly in those who took Viagra compared to those persons who received placebo tablets. The most common undesirable effect was headache, but it was mild. During the use of sildenafil, recurrence of depression was not observed.

In addition, scientists D. Stulberg and B. Ewigman conducted an interesting study in 2008, which allowed them to draw the following conclusions. If a doctor appoints SRIs to women, he should tell them to let him / her know if they have sexual dysfunction as a result of antidepressant therapy. Sildenafil (Viagra) in a dosage of 50 mg with the possibility of increasing to 100 mg will help women cope with this problem, scientists said. Hence, Female Viagra* is a good tool for eliminating antidepressant-induced sexual problems in women.

* For more information about Female Viagra, please visit this page: https://mycanadianhealthcaremall.com/product/female-pink-viagra/

Can Viagra Treat Depression?

Later, scientists from Canada made another interesting discovery. They found that Viagra not only can reduce the symptoms of antidepressant-associated erection problems, but also treat depression of a mild degree of severity. Dr. Sidney Kennedy, head of the research team, reported that many men with erectile dysfunction also have symptoms of depression. The study involved male persons who suffered erectile dysfunction for about 4 years and simultaneously had symptoms of mild depression.

Participants of the study were divided into two groups. The first group received sildenafil and the second one took placebo. Six weeks later, most men who used sildenafil reduced their depression rates by 47 percent, that is, their depression became minimal. Those who took placebo had only a 26% reduction in depression level, that is, their condition remained mild, not minimal. Of course, Viagra also improved penile erection and the quality of life in these men.

The Bottom Line

Viagra is a medical remedy that is very helpful in the case of erectile problems caused by the use of antidepressant meds, especially serotonin reuptake inhibitors. It improves the sexual life, and makes it possible to use the full cycle of treatment with antidepressants without canceling their administration.

In the treatment of erectile dysfunction and simultaneous presence of psychological problems, a psychologist’s consultation is required, since regardless of the cause of the problem (impotence), sexual failures cause serious damage to the psychological state of a person.

How Long Does Viagra Last and Smart Ways to Prolong its Effect

January 22, 2018/in Generic Viagra /by Douglas C. Goldberg, MD

Males who have decided to use Viagra often wonder: How long does Viagra last?

It is important for them to know how much time they have after taking the blue pill to plan sexual activity. In addition, they are certainly interested in being aware of how to prolong the effect of the med.

Fast Way: Viagra can last up to 5 hours!

Overview

Viagra was the 1st oral anti-ED (erectile dysfunction) medicament approved by the US FDA in 1998. It caused a revolution in the field of ED treatment. Despite the presence of competitors in the pharmaceutical market, such as Generic Cialis and Levitra, Viagra is still popular among males. In particular, Canadian Viagra is very popular due to its affordable price.

Additional information about Erectile Dysfunction in infographics: mycanadianhealthcaremall.com/erectile-dysfunction/

Viagra begins after 30-60min

How does it work?

In order to understand, when Viagra begins to act and how long it lasts in the body, first it is necessary to clarify the principle of its action. The drug is based on the active substance sildenafil, which belongs to the group of selective inhibitors of PDE5. The result of its use is relaxation of the muscles of the cavernous body of the penis and an increase in blood flow in this organ. The drug begins to act after entering the bloodstream, namely in 30-60 min after ingestion, and is commonly believed to be effective for 4 to 6 hours.

Extended Effect – the Research Data

It is believed that Viagra acts up to a maximum of 5 hours. This is indicated in the official manufacturer’s instructions and is based on the early studies (I. Eardley et al., 2002) which showed a peak concentration of sildenafil in the blood to be 60-120 min after administration of the medication. This peak concentration fell by about 50 percent approximately four hours after administration.

Therefore, initially, researchers stopped measuring the effectiveness within 4-6 hours after taking the blue pill.

However, soon some scientists went further and showed that in some men the effect might last longer.

For example, research by C. Gingell et al. (2004) published in The Journal of Sexual Medicine showed that Viagra could be active even after 12 hours. The men were divided into two groups. The first group took sildenafil and the second group was given placebo tablets. Participants in both groups were subjected to measuring the erection level 1, 8 or 12 hours before visual sexual stimulation. The scientists found that 82 percent of those who responded to sildenafil an hour later also achieved an erection after 8 hours, 45 percent – even after 12 hours. At the same time, the duration of penile erection with 60% or more rigidity was 26 minutes (after an hour), 11 minutes (after 8 hours) and 8 minutes (after 12 hours).

How Long Does Viagra Last?

Therefore, in some male persons, Generic Viagra may last up to 12 hours, but the duration of erection and/or its quality begins to decrease presumably within 2-4 hours after administration of the drug, according to other studies and users’ reviews.

how long does viagra last

Smart Ways to Prolong Viagra’s Effect

Generic Viagra works only when you are in mood and want to have a sexual intercourse. Four to six hours (sometimes more) is a fairly long period of time, but sometimes it may be not enough (or missed), especially given the fact that Viagra is not recommended to be taken more than 1 time per day.

Below are some tips you should follow if you want to prolong Viagra’s effect.

Eat well. Consuming a large amount of food, especially with a very high fat content, may delay the absorption of sildenafil. Accordingly, this can prolong the effect of the drug, but onset of this effect also will be delayed. Conversely, taking the drug in a fasted state will accelerate the onset of effect but the duration of it will be shorter.
Don’t eat grapefruit. The study by A. Jetter et al. (2002) showed that simultaneous consumption of grapefruit and the medicament increased the bioavailability of sildenafil by 23 percent. This makes the drug effect unpredictable and increases the development of various side effects, such as headache and face redness. Therefore, avoid grapefruit in any case, when undergoing treatment with the drug, regardless of whether you want to prolong the action of Viagra or not.
Don’t drink too much alcohol. Usually alcoholic drinks do not affect the level of sildenafil citrate in the blood and vice versa. Many men think that alcohol helps to relax & get in mood to sex, however its large dose can prevent a male person from achieving a penile erection. To make the effect of Viagra more predictable, avoid or minimize alcohol consumption.
Practice smart timing. The duration of action of the med varies from person to person, as you could understand from the research data that we cited above. It depends on the constitution of a person, metabolic rate, work of the gastrointestinal tract and individual sensitivity to sildenafil. Determine the average time of action of the drug on your body and in the future, plan your sexual activity in compliance with your individual response to administering Viagra.

It should also be noted that the effect of Viagra may be observed longer in men after 65 and in those who suffer from severe renal & liver diseases. This phenomenon is associated with a reduced rate of excretion of the drug from the body due to the slowing of metabolism in old age and the deteriorated functioning of natural “cleaners” of the body (liver and kidneys), respectively.

Viagra Produced in Canada

November 5, 2016/in Generic Viagra /by Douglas C. Goldberg, MD

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Viagra is sold actively due to its quality and accessibility. Those who buy such do not be afraid of been laughed at. Canadian Health Care Mall Pharmacy truly reverses end for end the approach of ordering drugs online. First of all you can walk up and down with their services. If you don’t know from what to start, here you will find the necessary information. Freely customer support, international shipping and low prices will assure you to command our service.

How to Take Viagra

how long Viagra works Before you buy Viagra online, you should be convinced if you can take the medicine correctly. Although Viagra should not be taken regularly. For example, you should take Viagra for forty minutes before apprehended sex intercourse and tried to have it. The effect of Viagra is temporal. The drug effect ends after some time after the end of sex intercourse.

Attention! Viagra Side Effects

However, once you take Viagra to receive an erection, it is much easier to get strong erection. It should be mentioned that you should not take Viagra more often than every twenty four hours to prevent the side effects appearance. The side effects appearance may be unpredictable in case of unbridled intake of drugs.

There are the following side effects caused by Viagra intake including headache, stuffy nose, dizziness, indigestion, skin burning. For more serious effects include itching, problems with the respiratory system, tumors of the face or its parts, chest pain, irregular heartbeat, memory impairment, painful or prolonged erection. Undoubtedly, this list is no way to complete.

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